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A novel, covalent broad-spectrum inhibitor targeting human coronavirus Mpro
Authors: Jing Sun, Deheng Sun, Qi Yang, Dong Wang, Jingjing Peng, Hu Guo, Xiaoyu Ding, Zhao Chen, Bin Yuan, Yan A Ivanenkov, Jinwei Yuan, Bogdan A Zagribelnyy, Yiyun He, Jingyi Su, Ling Wang, Jielin Tang, Zhun Li, Rong Li, Taotao Li, Xiaoyu Hu, Xing Liang, Airu Zhu, Peilan Wei, Yaya Fan, Sang Liu, Jie Zheng, Xin Guan, Alex Aliper, Minglei Yang, Dmitry S Bezrukov, Zhanhong Xie, Victor A Terentiev, Guilin Peng, Daniil A Polykovskiy, Alexander S Malyshev, Maxim N Malkov, Qingsong Zhu, Alán Aspuru-Guzik, Xiao Ding, Xin Cai, Man Zhang, Jingxian Zhao, Nanshan Zhong, Feng Ren, Xinwen Chen, Alex Zhavoronkov, Jincun Zhao
Journal: Nature Communications
PubMed ID: 40374668
Doi: 10.1038/s41467-025-59870-4
Products & Services: Peptide Synthesis   
Mechanism of D-type cyclin recognition by the AMBRA1 E3 ligase receptor
Authors: Yang Wang, Ming Liu, Shan Wang, Xinyi Mai, Xi Wang, Fei Teng, Tianrui Lyu, Ming-Yuan Su, Goran Stjepanovic
Journal: SCIENCE ADVANCES
PubMed ID: 40408472
Doi: 10.1126/sciadv.adu8708
Products & Services: Peptide Synthesis   
Expanding the σ54-dependent transcription process with orthogonal designs
Authors: Yiheng Liu, Shuyi Cai, Ziyi Zhang, Zhuoting Xie, Chenyue Guo, Yi-Ping Wang, Jianguo Yang
Journal: Nucleic Acids Research
PubMed ID: 40401558
Doi: 10.1093/nar/gkaf442
Products & Services: Gene Synthesis   
Hsc70-4: An unanticipated mediator of dsRNA internalization in Drosophila
Authors: Sabrina J Fletcher, Eugenia S Bardossy, Lorena Tomé-Poderti, Thomas Moss, Vanesa Mongelli, Lionel Frangeul, Hervé Blanc, Yann Verdier, Joelle Vinh, Shaeri Mukherjee, Maria-Carla Saleh
Journal: SCIENCE ADVANCES
PubMed ID: 40378201
Doi: 10.1126/sciadv.adv1286
Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens
Authors: Sifeng Gu , Zsolt Bodai , Rachel A Anderson , Hei Yu Annika So , Quinn T Cowan , Alexis C Komor
Journal: Nature Communications
PubMed ID: 40394064
Doi: 10.1038/s41467-025-59948-z
Accurate Mapping of 5-Glyceryl-methylcytosine Using Nanopore Sequencing
Authors: Linting Wang, Baodan He, Zixin Wang, Liting Kang, Jianhuang Xue, Shuanghong Yan
Journal: Anal Chem
PubMed ID: 40314134
Doi: 10.1021/acs.analchem.5c00845
Products & Services: Plasmid DNA Preparation   Custom RNAi Services   
Inhalable myofibroblast targeting nanoparticles for synergistic treatment of pulmonary fibrosis
Authors: Zhike Chen, Jian Yang, Qiang Zhang, Weibiao Zeng, Yi Liu, Wenxuan Hu, Linfu Chen, Jingjing Shen, Yu Miao, Zhisheng Xiao, Zhiqiang Wu, He Wang, Hui Shen, Cheng Ding, Qian Chen, Jun Zhao, Yang Yang
Journal: SCIENCE ADVANCES
PubMed ID: 40305619
Doi: 10.1126/sciadv.adv9571
Products & Services: Protein and Antibody Isolation   
Nanofabricated Bacterial Cell Walls with Intrinsic Peroxidase-Mimicking and Sonodynamic Activities for Cancer Combination Treatment
Authors: Meng Yang, Yang Meng, Junling Li, Liya Bai, Yuanyuan Cheng, Yuanyuan Liu, Mingxin Cao, Xiaoying Yang, Yinsong Wang, Yang Liu
Journal: Adv Sci (Weinh)
PubMed ID: 40365750
Doi: 10.1002/advs.202505310
Products & Services: Endotoxin Detection & Removal System   
De novo assembly of nuclear stress bodies rearranges and enhances NFIL3 to restrain acute inflammatory responses
Authors: Xiao-Qi Liu, Pan Li, Bao-Qing Gao, Heng-Le Zhu, Liang-Zhong Yang, Yang Wang, Yu-Yao Zhang, Hao Wu, Yu-Hang Pan, Lin Shan, Hongtao Yu, Li Yang, Ling-Ling Chen
Journal: Cell
PubMed ID: 40436014
Doi: 10.1016/j.cell.2025.05.003
Products & Services: Custom RNAi Services   
Structural basis of augmenting taurine uptake by the taurine transporter in alleviating cellular senescence
Authors: Heng Zhang, Nana Cui, Xiong Ma, H Eric Xu
Journal: Cell Research
PubMed ID: 40108449
Doi: 10.1038/s41422-025-01090-y
Products & Services: Protein and Antibody Isolation   
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