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Growth State-Dependent Expression of Arachidonate Lipoxygenases in the Human Endothelial Cell Line EAhy926

Authors: Mohammad G Sabbir, Jeffrey T Wigle, Carla G Taylor, Peter Zahradka

Journal: Cells

PubMed ID: 36010555

Doi: 10.3390/cells11162478

Products & Services: ORF cDNA Clones/MolecularCloud

Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms

Authors: Laura J Stevens, Andrea J Pruijssers, Hery W Lee, Calvin J Gordon, Egor P Tchesnokov, Jennifer Gribble, Amelia S George, Tia M Hughes, Xiaotao Lu, Jiani Li, Jason K Perry, Danielle P Porter, Tomas Cihlar, Timothy P Sheahan, Ralph S Baric, Matthias Götte, Mark R Denison

Journal: Sci Transl Med

PubMed ID: 35482820

Doi: 10.1126/scitranslmed.abo0718

Products & Services: Plasmid DNA Preparation

assessment of simultaneous G1 cyclins silencing by a tumor-specific bidirectional promoter on the mammary tumor in nude mice

Authors: Gholamreza Mesbah, Fatemeh Namazi, Fatemeh T Shamsabadi, Zahra Maleki, Mehrab Nasirikenari, Majid Shahbazi

Journal: Front Vet Sci

PubMed ID: 36072388

Doi: 10.3389/fvets.2022.914311

Products & Services: Custom Vector Construction

The Catalytic Subunit of CK2 (Cka1) Negatively Regulates RNA Polymerase II Transcription through Phosphorylation of Positive Cofactor 4 (PC4)

Authors: Diego A Rojas, Fabiola Urbina, Aldo Solari, Edio Maldonado

Journal: Int J Mol Sci

PubMed ID: 36012759

Doi: 10.3390/ijms23169499

Products & Services: Mutant Libraries

Transcriptional changes in LMH cells induced by rhoptry kinase family protein 17

Authors: Yi-Jing Meng, Bing-Jin Mu, Xiao-Xin Liu, Lin-Mei Yu, Wen-Bin Zheng, Shi-Chen Xie, Wen-Wei Gao, Xing-Quan Zhu, Qing Liu

Journal: Front Vet Sci

PubMed ID: 36016802

Doi: 10.3389/fvets.2022.956040

Products & Services: Protein and Antibody Isolation

Structural basis for receptor selectivity and inverse agonism in S1P receptors

Authors: Elizaveta Lyapina, Egor Marin, Anastasiia Gusach, Philipp Orekhov, Andrey Gerasimov, Aleksandra Luginina, Daniil Vakhrameev, Margarita Ergasheva, Margarita Kovaleva, Georgii Khusainov, Polina Khorn, Mikhail Shevtsov, Kirill Kovalev, Sergey Bukhdruker, Ivan Okhrimenko, Petr Popov, Hao Hu, Uwe Weierstall, Wei Liu, Yunje Cho, Ivan Gushchin, Andrey Rogachev, Gleb Bourenkov, Sehan Park, Gisu Park, Hyo Jung Hyun, Jaehyun Park, Valentin Gordeliy, Valentin Borshchevskiy, Alexey Mishin, Vadim Cherezov

Journal: Nat Commun

PubMed ID: 35961984

Doi: 10.1038/s41467-022-32447-1

Products & Services: Mammalian Expression

Strong T-cell activation in response to COVID-19 vaccination in multiple sclerosis patients receiving B-cell depleting therapies

Authors: Roberto Alfonso-Dunn, Jerry Lin, Vanessa Kirschner, Joyce Lei, Grant Feuer, Michaela Malin, Jiayuan Liu, Morgan Roche, Saud A Sadiq

Journal: Front Immunol

PubMed ID: 35990701

Doi: 10.3389/fimmu.2022.926318

Immunogenicity and Protective Efficacy of a Recombinant Pichinde Viral-Vectored Vaccine Expressing Influenza Virus Hemagglutinin Antigen in Pigs

Authors: Sushmita Kumari, Jayeshbhai Chaudhari, Qinfeng Huang, Phillip Gauger, Marcelo Nunes De Almeida, Yuying Liang, Hinh Ly, Hiep L X Vu

Journal: Vaccines (Basel)

PubMed ID: 36146478

Doi: 10.3390/vaccines10091400

Products & Services: Gene Synthesis

Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure

Authors: Eva K Oernbo, Annette B Steffensen, Pooya Razzaghi Khamesi, Trine L Toft-Bertelsen, Dagne Barbuskaite, Frederik Vilhardt, Niklas J Gerkau, Katerina Tritsaris, Anja H Simonsen, Sara D Lolansen, Søren N Andreassen, Steen G Hasselbalch, Thomas Zeuthen, Christine R Rose, Vartan Kurtcuoglu, Nanna MacAulay

Journal: Fluids Barriers CNS

PubMed ID: 36038945

Doi: 10.1186/s12987-022-00358-4

Products & Services: Gene Synthesis

Translational potential of base-editing tools for gene therapy of monogenic diseases

Authors: Vasiliy V Reshetnikov, Angelina V Chirinskaite, Julia V Sopova, Roman A Ivanov, Elena I Leonova

Journal: Front Bioeng Biotechnol

PubMed ID: 36032737

Doi: 10.3389/fbioe.2022.942440

Products & Services: Codon Optimization