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Intramuscular delivery of formulated RNA encoding six linked nanobodies is highly protective for exposures to three Botulinum neurotoxin serotypes

Authors: Jean Mukherjee, Celinia A Ondeck, Jacqueline M Tremblay, Jacob Archer, Michelle Debatis, Alexa Foss, Junya Awata, Jesse H Erasmus, Patrick M McNutt, Charles B Shoemaker

Journal: Sci Rep

PubMed ID: 35803998

Doi: 10.1038/s41598-022-15876-2

Products & Services: Gene Synthesis

Characterization of binding interactions of SARS-CoV-2 spike protein and DNA-peptide nanostructures

Authors: Marlen Kruse, Basma Altattan, Eva-Maria Laux, Nico Grasse, Lars Heinig, Christin Möser, David M Smith, Ralph Hölzel

Journal: Sci Rep

PubMed ID: 35896714

Doi: 10.1038/s41598-022-16914-9

Products & Services: Catalog Peptides

Mucosal administration of a live attenuated recombinant COVID-19 vaccine protects nonhuman primates from SARS-CoV-2

Authors: Mariana F Tioni, Robert Jordan, Angie Silva Pena, Aditya Garg, Danlu Wu, Shannon I Phan, Christopher M Weiss, Xing Cheng, Jack Greenhouse, Tatyana Orekov, Daniel Valentin, Swagata Kar, Laurent Pessaint, Hanne Andersen, Christopher C Stobart, Melissa H Bloodworth, R Stokes Peebles, Yang Liu, Xuping Xie, Pei-Yong Shi, Martin L Moore, Roderick S Tang

Journal: npj Vaccines

PubMed ID: 35906244

Doi: 10.1038/s41541-022-00509-6

Products & Services: Protein and Antibody Isolation

Polymeric nanoparticles for dual-targeted theranostic gene delivery to hepatocellular carcinoma

Authors: Hannah J Vaughan, Camila G Zamboni, Laboni F Hassan, Nicholas P Radant, Desmond Jacob, Ronnie C Mease, Il Minn, Stephany Y Tzeng, Kathleen L Gabrielson, Pranshu Bhardwaj, Xin Guo, David Francisco, Martin G Pomper, Jordan J Green

Journal: Sci Adv

PubMed ID: 35857843

Doi: 10.1126/sciadv.abo6406

Products & Services: Gene Synthesis

Highly Effective Markerless Genetic Manipulation of Using a Mutated PheS-Based Counterselectable Marker

Authors: Guangjuan Gao, Dong Wei, Gang Li, Ping Chen, Liujun Wu, Siguo Liu, Yueling Zhang

Journal: Front Microbiol

PubMed ID: 35910605

Doi: 10.3389/fmicb.2022.947821

Products & Services: Peptide Synthesis

CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7

Authors: Yong Zi Tan, Yazan M Abbas, Jing Ze Wu, Di Wu, Kristine A Keon, Geoffrey G Hesketh, Stephanie A Bueler, Anne-Claude Gingras, Carol V Robinson, Sergio Grinstein, John L Rubinstein

Journal: Life Sci Alliance

PubMed ID: 35794005

Doi: 10.26508/lsa.202201527

Products & Services: Custom Vector Construction

Neutralizing antibody responses against SARS-CoV-2 in patients with plasma cell disorders who are on active treatment after two doses of mRNA vaccination

Authors: Al-Ola Abdallah, Zahra Mahmoudjafari, Tahani Atieh, Nausheen Ahmed, Wei Cui, Leyla Shune, Meera Mohan, Joseph McGuirk, Cassie Remker, Margaret Foss, Ellie Karloff, Heather Fitch, Shebli Atrash

Journal: Eur J Haematol

PubMed ID: 35810359

Doi: 10.1111/ejh.13826

Cryo-EM structures of human fucosidase FucA1 reveal insight into substrate recognition and catalysis

Authors: Zachary Armstrong, Richard W Meek, Liang Wu, James N Blaza, Gideon J Davies

Journal: Structure

PubMed ID: 35907402

Doi: 10.1016/j.str.2022.07.001

Products & Services: Mutant Libraries

Comprehensive Evaluation and Comparison of Machine Learning Methods in QSAR Modeling of Antioxidant Tripeptides

Authors: Zhenjiao Du, Donghai Wang, Yonghui Li

Journal: ACS Omega

PubMed ID: 35910147

Doi: 10.1021/acsomega.2c03062

Products & Services: Peptide Synthesis

Relaxin Affects Airway Remodeling Genes Expression through Various Signal Pathways Connected with Transcription Factors

Authors: Joanna Wieczfinska, Rafal Pawliczak

Journal: Int J Mol Sci

PubMed ID: 35955554

Doi: 10.3390/ijms23158413

Products & Services: Protein Electrophoresis and Western