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Scalable biological signal recording in mammalian cells using Cas12a base editors

Authors: Hannah R Kempton, Kasey S Love, Lucie Y Guo, Lei S Qi

Journal: Nat Chem Biol

PubMed ID: 35637351

Doi: 10.1038/s41589-022-01034-2

Products & Services: ELISA Kits

Convergent Alterations of a Protein Hub Produce Divergent Effects within a Binding Site

Authors: Ali Imran, Brandon S Moyer, Dan Kalina, Thomas M Duncan, Kelsey J Moody, Aaron J Wolfe, Michael S Cosgrove, Liviu Movileanu

Journal: ACS Chem Biol

PubMed ID: 35613319

Doi: 10.1021/acschembio.2c00273

Products & Services: Protein and Antibody Isolation

The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer

Authors: Almutasem Saleh, Yasunori Noguchi, Ricardo Aramayo, Marina E Ivanova, Kathryn M Stevens, Alex Montoya, S Sunidhi, Nicolas Lopez Carranza, Marcin J Skwark, Christian Speck

Journal: Nat Commun

PubMed ID: 35614055

Doi: 10.1038/s41467-022-30576-1

Products & Services: Mutant Libraries

Correlation Analysis of Anti-SARS-CoV-2 RBD IgG and Neutralizing Antibody against SARS-CoV-2 Omicron Variants after Vaccination

Authors: Nuchjira Takheaw, Chalerm Liwsrisakun, Warawut Chaiwong, Witida Laopajon, Supansa Pata, Juthamas Inchai, Pilaiporn Duangjit, Chaicharn Pothirat, Chaiwat Bumroongkit, Athavudh Deesomchok, Theerakorn Theerakittikul, Atikun Limsukon, Pattraporn Tajarernmuang, Nutchanok Niyatiwatchanchai, Konlawij Trongtrakul, Watchara Kasinrerk

Journal: Diagnostics (Basel)

PubMed ID: 35741126

Doi: 10.3390/diagnostics12061315

The phosphatase PTEN links platelets with immune regulatory functions of mouse T follicular helper cells

Authors: Xue Chen, Yanyan Xu, Qidi Chen, Heng Zhang, Yu Zeng, Yan Geng, Lei Shen, Fubin Li, Lei Chen, Guo-Qiang Chen, Chuanxin Huang, Junling Liu

Journal: Nat Commun

PubMed ID: 35589797

Doi: 10.1038/s41467-022-30444-y

Products & Services: Catalog Antibodies

Durable immunogenicity, adaptation to emerging variants, and low-dose efficacy of an AAV-based COVID-19 vaccine platform in macaques

Authors: Nerea Zabaleta, Urja Bhatt, Cécile Hérate, Pauline Maisonnasse, Julio Sanmiguel, Cheikh Diop, Sofia Castore, Reynette Estelien, Dan Li, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouët, Quentin Pascal, Thibaut Naninck, Nidhal Kahlaoui, Julien Lemaitre, Francis Relouzat, Giuseppe Ronzitti, Hendrik Jan Thibaut, Emanuele Montomoli, James M Wilson, Roger Le Grand, Luk H Vandenberghe

Journal: Mol Ther

PubMed ID: 35546782

Doi: 10.1016/j.ymthe.2022.05.007

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Overdominant and partially dominant mutations drive clonal adaptation in diploid Saccharomyces cerevisiae

Authors: Dimitra Aggeli, Daniel A Marad, Xianan Liu, Sean W Buskirk, Sasha F Levy, Gregory I Lang

Journal: Genetics

PubMed ID: 35435209

Doi: 10.1093/genetics/iyac061

Products & Services: Plasmid DNA Preparation

Validated determination of NRG1 Ig-like domain structure by mass spectrometry coupled with computational modeling

Authors: Niloofar Abolhasani Khaje, Alexander Eletsky, Sarah E Biehn, Charles K Mobley, Monique J Rogals, Yoonkyoo Kim, Sushil K Mishra, Robert J Doerksen, Steffen Lindert, James H Prestegard, Joshua S Sharp

Journal: Commun Biol

PubMed ID: 35551273

Doi: 10.1038/s42003-022-03411-y

Products & Services: Plasmid DNA Preparation

Specific bio-functional CBD-PR1P peptide binding VEGF to collagen hydrogels promotes the recovery of cerebral ischemia in rats

Authors: Jia Yin, Chunying Shi, Wenli He, Wenjing Yan, Jin Deng, Bing Zhang, Mengmeng Yin, Haitao Pei, Haiping Wang

Journal: J Biomed Mater Res A

PubMed ID: 35603700

Doi: 10.1002/jbm.a.37409

Products & Services: Protein and Antibody Isolation

Structural basis for the synthesis of the core 1 structure by C1GalT1

Authors: Andrés Manuel González-Ramírez, Ana Sofia Grosso, Zhang Yang, Ismael Compañón, Helena Coelho, Yoshiki Narimatsu, Henrik Clausen, Filipa Marcelo, Francisco Corzana, Ramon Hurtado-Guerrero

Journal: Nat Commun

PubMed ID: 35504880

Doi: 10.1038/s41467-022-29833-0

Products & Services: Codon Optimization