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Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of PETase and Variants with Improved Stability and Activity

Authors: Yvonne Joho, Vanessa Vongsouthi, Matthew A Spence, Jennifer Ton, Chloe Gomez, Li Lynn Tan, Joe A Kaczmarski, Alessandro T Caputo, Santana Royan, Colin J Jackson, Albert Ardevol

Journal: Biochemistry

PubMed ID: 35951410

Doi: 10.1021/acs.biochem.2c00323

Products & Services: Protein and Antibody Isolation

Rabbit hemorrhagic disease virus VP60 protein expressed in recombinant swinepox virus self-assembles into virus-like particles with strong immunogenicity in rabbits

Authors: Changjin Liu, Min Lin, Huanyi Hu, Xiaolan Liu, Yanchao Bian, Xiaohua Huang, Xiaoxiang Li, Wenyang Yu, Feng Luo, Shunzhou Deng

Journal: Front Microbiol

PubMed ID: 35992711

Doi: 10.3389/fmicb.2022.960374

Products & Services: Plasmid DNA Preparation

Investigation of Transcript Variant 6 of as a Prognostic and Predictive Biomarker in Basal-Like MDA-MB-231 and MDA-MB-453 Cell Lines for Breast Cancer

Authors: Xin Zhang, Daniel O'Brien, Xiaohui Zhang

Journal: Oxid Med Cell Longev

PubMed ID: 36071863

Doi: 10.1155/2022/7078787

Products & Services: Plasmid DNA Preparation

TLNRD1 is a CCM complex component and regulates endothelial barrier integrity

Authors: Neil J. Ball; Sujan Ghimire; Gautier Follain; Ada O. Pajari; Diana Wurzinger; Monika Vaitkevi i t ; Alana R. Cowell; Bence Berki; Johanna Ivaska; Ilkka Paatero; Benjamin T. Goult; Guillaume Jacquemet

Journal: The Journal of cell biology

PubMed ID: 39013281

Doi: 10.1083/jcb.202310030

Expedient Synthesis of Ubiquitin-like Protein ISG15 Tools Through Chemo-Enzymatic Ligation Catalyzed by a Viral Protease Lbpro

Authors: Tian Wang , Chuntong Li , Meijing Wang , Jiachen Zhang , Qingyun Zheng , Lujun Liang , Guochao Chu , Xiaolin Tian , Haiteng Deng , Wei He , Lei Liu , Jinghong Li

Journal: Angew Chem Int Ed Engl

PubMed ID: 35962463

Doi: 10.1002/anie.202206205

Products & Services: Gene Synthesis

Enhancing the Catalytic Activity of Type II L-Asparaginase from Bacillus licheniformis through Semi-Rational Design

Authors: Yawen Zhou ,Linshu Jiao ,Juan Shen ,Huibing Chi ,Zhaoxin Lu ,Huawei Liu ,Fengxia Lu ,Ping Zhu

Journal: Int J Mol Sci

Doi: 10.3390/ijms23179663

Products & Services: Gene Synthesis

Dry powder inhalation technology for heart targeting applied to calcium phosphate nanoparticles loaded with active substances

Authors: Eride Quarta,Lorenzo Degli Esposti, Ruggero Bettini ,Fabio Sonvico ,Daniele Catalucci , Michele Iafisco ,Claudio De Luca ,Giovanna Trevisi ,Paolo Colombo ,Alessandra Rossi ,Francesca Buttini , Gaia Colombo

Journal: Drug Delivery Science and Technology

Doi: doi.org/10.1016/j.jddst.2022.103719

Products & Services: Peptide Synthesis

Receptor deorphanization in an echinoderm reveals kisspeptin evolution and relationship with SALMFamide neuropeptides

Authors: Nayeli Escudero Castelán , Dean C Semmens , Luis Alfonso Yañez Guerra , Meet Zandawala , Mario Dos Reis , Susan E Slade , James H Scrivens , Cleidiane G Zampronio , Alexandra M Jones , Olivier Mirabeau , Maurice R Elphick

Journal: BMC Biol

PubMed ID: 36002813

Doi: 10.1186/s12915-022-01387-z

Products & Services: Gene Synthesis

The neurodevelopmental gene MSANTD2 belongs to a gene family formed by recurrent molecular domestication of Harbinger transposons at the base of vertebrates

Authors: Ema Etchegaray, Dominique Baas, Magali Naville, Zofia Haftek-Terreau, Jean Nicolas Volff

Journal: Mol Biol Evol

PubMed ID: 35980103

Doi: 10.1093/molbev/msac173

Products & Services: Custom Vector Construction

Human Claudin-Derived Peptides Block the Membrane Fusion Process of Zika Virus and Are Broad Flavivirus Inhibitors

Authors: Jim Zoladek, Julien Burlaud-Gaillard, Maxime Chazal, Sophie Desgraupes, Patricia Jeannin, Antoine Gessain, Nathalie Pardigon, Mathieu Hubert, Philippe Roingeard, Nolwenn Jouvenet, Philippe V Afonso

Journal: Microbiol Spectr

PubMed ID: 36040168

Doi: 10.1128/spectrum.02989-22

Products & Services: Peptide Synthesis