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Ubiquitylation is required for the incorporation of the Notch receptor into intraluminal vesicles to prevent prolonged and ligand-independent activation of the pathway

Authors: Björn Schnute, Hideyuki Shimizu, Marvin Lyga, Martin Baron, Thomas Klein

Journal: BMC Biol

PubMed ID: 35264151

Doi: 10.1186/s12915-022-01245-y

Products & Services: Gene Synthesis

Tumor-reactive antibodies evolve from non-binding and autoreactive precursors

Authors: Roei D Mazor, Nachum Nathan, Amit Gilboa, Liat Stoler-Barak, Lihee Moss, Inna Solomonov, Assaf Hanuna, Yalin Divinsky, Merav D Shmueli, Hadas Hezroni, Irina Zaretsky, Michael Mor, Ofra Golani, Gad Sabah, Ariella Jakobson-Setton, Natalia Yanichkin, Meora Feinmesser, Daliah Tsoref, Lina Salman, Effi Yeoshoua, Eyal Peretz, Inna Erlich, Netta Mendelson Cohen, Jonathan M Gershoni, Natalia Freund, Yifat Merbl, Gur Yaari, Ram Eitan, Irit Sagi, Ziv Shulman

Journal: Cell

PubMed ID: 35305314

Doi: 10.1016/j.cell.2022.02.012

Products & Services: Catalog Peptides

Phosphorylation but Not Oligomerization Drives the Accumulation of Tau with Nucleoporin Nup98

Authors: Lisa Diez, Larisa E Kapinos, Janine Hochmair, Sabrina Huebschmann, Alvaro Dominguez-Baquero, Amelie Vogt, Marija Rankovic, Markus Zweckstetter, Roderick Y H Lim, Susanne Wegmann

Journal: Int J Mol Sci

PubMed ID: 35408855

Doi: 10.3390/ijms23073495

Products & Services: Plasmid DNA Preparation

Genome-wide investigation of maize RAD51 binding affinity through phage display

Authors: Claire Milsted, Bo Dai, Nelson Garcia, Lu Yin, Yan He, Shahryar Kianian, Wojciech Pawlowski, Changbin Chen

Journal: BMC Genomics

PubMed ID: 35279087

Doi: 10.1186/s12864-022-08419-6

Products & Services: Catalog Peptides

Defining Biomarkers to Predict Natural Resolution in Shrimp Allergy

Authors: Surapon Piboonpocanun, Suttipong Ittiporn, Pisit Ubonsri, Anchalee Wangtan, Punchama Pacharn, Nualanong Visitsunthorn, Orathai Jirapongsananuruk

Journal: Allergy Asthma Immunol Res

PubMed ID: 35255538

Doi: 10.4168/aair.2022.14.2.210

Products & Services: Protein and Antibody Isolation

Enantioselectivity and key residue of Herbaspirillum huttiense monooxygenase in asymmetric epoxidation of styrenes

Authors: Shuang Dong, Donglin Fan, Qian Liu, Yinyin Meng, Xinyu Liu, Sen Yang, Hui Lin, Na Li, Hongge Chen

Journal: Appl Microbiol Biotechnol

PubMed ID: 35230494

Doi: 10.1007/s00253-022-11843-z

Products & Services: Protein Electrophoresis and Western

Efficient C-to-G Base Editing with Improved Target Compatibility Using Engineered Deaminase-nCas9 Fusions

Authors: Siyu Chen, Zhiquan Liu, Liangxue Lai, Zhanjun Li

Journal: CRISPR J

PubMed ID: 35238619

Doi: 10.1089/crispr.2021.0124

Products & Services: Gene Fragments

Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain

Authors: Gang Ye, Bin Liu, Fang Li

Journal: Nat Commun

PubMed ID: 35241675

Doi: 10.1038/s41467-022-28882-9

Products & Services: Gene Synthesis

A rulebook for peptide control of legume-microbe endosymbioses

Authors: Sonali Roy, Lena Maria Müller

Journal: Trends Plant Sci

PubMed ID: 35246381

Doi: 10.1016/j.tplants.2022.02.002

Products & Services: Peptide Synthesis

mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice

Authors: Zekun Mu, Kevin Wiehe, Kevin O Saunders, Rory Henderson, Derek W Cain, Robert Parks, Diana Martik, Katayoun Mansouri, Robert J Edwards, Amanda Newman, Xiaozhi Lu, Shi-Mao Xia, Amanda Eaton, Mattia Bonsignori, David Montefiori, Qifeng Han, Sravani Venkatayogi, Tyler Evangelous, Yunfei Wang, Wes Rountree, Bette Korber, Kshitij Wagh, Ying Tam, Christopher Barbosa, S Munir Alam, Wilton B Williams, Ming Tian, Frederick W Alt, Norbert Pardi, Drew Weissman, Barton F Haynes

Journal: Cell Rep

PubMed ID: 35294883

Doi: 10.1016/j.celrep.2022.110514

Products & Services: Gene Synthesis