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Highly biased agonism for GPCR ligands via nanobody tethering

Authors: Shivani Sachdev, Brendan A Creemer, Thomas J Gardella, Ross W Cheloha

Journal: Nat Commun

PubMed ID: 38824166

Doi: 10.1038/s41467-024-49068-5.

Products & Services: Protein and Antibody Isolation PCR Cloning and Subcloning

A growth selection system for sucrose synthases (SuSy): design and test

Authors: Gonzalo N Bidart, Se Hyeuk, Tobias Benedikt Alter, Lei Yang, Ditte Hededam Welner

Journal: AMB Express

PubMed ID: 38865019

Doi: 10.1186/s13568-024-01727-y

Products & Services: Molecular Biology Reagents

BRET-based biosensors for SARS-CoV-2 oligonucleotide detection

Authors: Asfia Sultana, Anupriya M Geethakumari, Zeyaul Islam, Prasanna R Kolatkar, Kabir H Biswas

Journal: Front Bioeng Biotechnol

PubMed ID: 38887615

Doi: 10.3389/fbioe.2024.1353479

Products & Services: Protein and Antibody Isolation

Next-generation nanovaccine induces durable immunity and protects against SARS-CoV-2

Authors: Kathleen A Ross, Sean Kelly, Kruttika S Phadke, Nathan Peroutka-Bigus, Olufemi Fasina, Alaric Siddoway, Surya K Mallapragada, Michael J Wannemuehler, Bryan H Bellaire, Balaji Narasimhan

Journal: Acta Biomater

PubMed ID: 38844193

Doi: 10.1016/j.actbio.2024.05.048

Products & Services: Molecular Biology Reagents

Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design

Authors: Manjeet Mukherjee, Philip J Day, Duncan Laverty, Juan A Bueren-Calabuig, Andrew J Woodhead, Charlotte Griffiths-Jones, Steve Hiscock, Charlotte East, Susan Boyd, Marc O'Reilly

Journal: Structure

PubMed ID: 38870939

Doi: 10.1016/j.str.2024.05.011

Products & Services: Custom Vector Construction

Repeat controlled human Plasmodium falciparum infections delay bloodstream patency and reduce symptoms

Authors: Patricia Ferrer, Andrea A Berry, Allison N Bucsan, Surendra K Prajapati, Karthik Krishnan, Michelle C Barbeau, David M Rickert, Sandra Mendoza Guerrero, Miho Usui, Yonas Abebe, Asha Patil, Sumana Chakravarty, Peter F Billingsley, Faith Pa'ahana-Brown, Kathy Strauss, Biraj Shrestha, Effie Nomicos, Gregory A Deye, B Kim Lee Sim, Stephen L Hoffman, Kim C Williamson, Kirsten E Lyke

Journal: Nat Commun

PubMed ID: 38890271

Doi: 10.1038/s41467-024-49041-2

Products & Services: Catalog Peptides

The generation of stable transgenic lines in the human-infective nematode Strongyloides stercoralis

Authors: Ruhi Patel, Astra S Bryant, Michelle L Castelletto, Breanna Walsh, Damia Akimori, Elissa A Hallem

Journal: G3 (Bethesda)

PubMed ID: 38839055

Doi: 10.1093/g3journal/jkae122

Products & Services: Molecular Biology Reagents

The role of shear forces in primary and secondary nucleation of amyloid fibrils

Authors: Emil Axell, Jing Hu, Max Lindberg, Alexander J Dear, Lei Ortigosa-Pascual, Ewa A Andrzejewska, Greta Šneiderienė, Dev Thacker, Tuomas P J Knowles, Emma Sparr, Sara Linse

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38875148

Doi: 10.1073/pnas.2322572121

Products & Services: Molecular Biology Reagents

The BICD2 dynein cargo adaptor binds to the HPV16 L2 capsid protein and promotes HPV infection

Authors: Kaitlyn Speckhart, Jeongjoon Choi, Daniel DiMaio, Billy Tsai

Journal: PLoS Pathog

PubMed ID: 38829892

Doi: 10.1371/journal.ppat.1012289

Products & Services: Catalog Peptides

Dual-Omics Approach Unveils Novel Perspective on the Quality Control of Genetically Engineered Exosomes

Authors: Christopher Olson, Konstantin Ivanov, Darin Boyes, David Bengford, Joy Ku, Renceh Flojo, Pengyang Zhang, Biao Lu

Journal: Pharmaceutics

PubMed ID: 38931944

Doi: 10.3390/pharmaceutics16060824

Products & Services: Molecular Biology Reagents