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Inflammatory macrophage-derived itaconate inhibits DNA demethylase TET2 to prevent excessive osteoclast activation in rheumatoid arthritis

Authors: Kewei Rong, Dezheng Wang, Xiting Pu, Cheng Zhang, Pu Zhang, Xiankun Cao, Jinglin Zheng, Xiao Yang, Kexin Liu, Lei Shi, Yin Li, Peixiang Ma, Dan Ye, Jie Zhao, Pu Wang, An Qin

Journal: Bone Research

PubMed ID: 40500265

Doi: 10.1038/s41413-025-00437-w

Products & Services: Protein and Antibody Isolation

Synthesis of an E2-Ub-nucleosome conjugate to capture the E3 ligase PHF7-catalyzed H3K14 ubiquitination intermediate

Authors: Shixian Tao, Wei He, Chuntong Li, Jiawei Liang, Zebin Tong, Zhiheng Deng, Liying Zhang, Huasong Ai, Lu-Jun Liang, Lei Liu

Journal: Science China-Chemistry

Doi: 10.1007/s11426-025-2697-6

Products & Services: PCR Cloning and Subcloning

A MERS-CoV-like mink coronavirus uses ACE2 as an entry receptor

Authors: Ningning Wang, Weiwei Ji, Houqi Jiao, Michael Veit, Ju Sun, Yanjun Wang, Xing Ma, Yu Wang, Yutong Wang, Xin-Xin Li, Xiaoguang Zhang, Jie Chen, Jiayu Wei, Ying Xu, Dawei Guo, Xiaofeng Zhai, Andres Merits, Chang Li, Félix A Rey, Georgi M Dobrikov, George F Gao, Shuijun Zhang, Yuhai Bi, Shuo Su

Journal: Nature

PubMed ID: 40306315

Doi: 10.1038/s41586-025-09007-w

Products & Services: Monoclonal Antibody Services

A New Vaccine Candidate Expressing JUNV GP1–GP2 Against Argentine Hemorrhagic Fever Based on Baculovirus Surface Display

Authors: Carla Tomatis, Mara C A M Aguiar, Nancy Charo, Silvia Aquila, Pablo D Thomas, Paula N Arrías, Matías L Pidre, Víctor Romanowski, Laura Riera, Julia Brignone, Andrea Maiza, Eugenio Antonio Carrera Silva, María Florencia Ferrer, Ricardo Martín Gómez

Journal: Current microbiology

PubMed ID: 40514553

Doi: 10.1007/s00284-025-04320-z

Products & Services: Gene Synthesis

Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III

Authors: Conor James McClune, Jack Chun-Ting Liu, Chloe Wick, Ricardo De La Peña, Bernd Markus Lange, Polly M Fordyce, Elizabeth S Sattely

Journal: Nature

PubMed ID: 40500440

Doi: 10.1038/s41586-025-09090-z

Products & Services: Protein and Antibody Isolation

Multiple intramolecular triggers converge to preferential G protein coupling in the CB2R

Authors: Adrian Morales-Pastor, Tamara Miljuš, Miguel Dieguez-Eceolaza, Tomasz Maciej Stępniewski, Vicente Ledesma-Martin, Franziska M Heydenreich, Tilman Flock, Bianca Plouffe, Christian Le Gouill, Jean Duchaine, David A Sykes, Colin Nicholson, Eline J Koers, Wolfgang Guba, Arne C Rufer, Uwe Grether, Michel Bouvier, Dmitry B Veprintsev, Jana Selent

Journal: Nature Communications

PubMed ID: 40500255

Doi: 10.1038/s41467-025-60003-0.

Products & Services: Catalog Antibodies

GhTOPP4aD and GhRAF36 inversely regulate cotton (Gossypium hirsutum) response to ABA and salt stress through reversible phosphorylation of GhABI1

Authors: Pengfei Cao, Lin Zhou, Mingwei Du, Xiaoli Tian, Fangjun Li, Zhaohu Li

Journal: Plant Biotechnology Journal.

PubMed ID: 40483577

Doi: 10.1111/pbi.70166

Products & Services: Polyclonal Antibody Services

Deciphering the role of accessory proteins in Arabidopsis chloroplast editosomes via interaction with a synthetic PPR-PLS factor in E. coli

Authors: Jose M Lombana , Maureen R Hanson , Stéphane Bentolila

Journal: Nucleic Acids Research

PubMed ID: 40498070

Doi: 10.1093/nar/gkaf483

Products & Services: Gene Synthesis

β-propeller protein-associated neurodegeneration protein WDR45 regulates stress granule disassembly via phase separation with Caprin-1

Authors: Yin Li, Jie Fang, Yuqi Ding, Xilong Zhang, Ying Liu, Wanting Qiu, He Xu, Yunzhe Kang, Jiayu Chen, Yanyan Gao, Yan G Zhao, Peiguo Yang, Bo Wang, Wenmin Tian, Yang Chen, Wenjian Bi, Peipei Zhang

Journal: Nature Communications

PubMed ID: 40473629

Doi: 10.1038/s41467-025-60583-x

Products & Services: Protein and Antibody Isolation

An Engineered Soluble Single-Chain TCR Engager for KRAS-G12V Specific Tumor Immunotherapy

Authors: Keke Ma, Jie Wang, Min Jiang, Juanhua He, Fangyang Li, Dan Lu, Chao Su, Yan Chai, Wenjing Jin, Yu Chen, Catherine W H Zhang, Xiaopeng Ma, Hui Tan, George F Gao, Shuguang Tan

Journal: Advanced Science

PubMed ID: 40470869

Doi: 10.1002/advs.202500181

Products & Services: Peptide Synthesis