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Cancer stem cell antigen nanodisc cocktail elicits anti-tumor immune responses in melanoma

Authors: Marisa E Aikins, You Qin, Hannah E Dobson, Alireza Hassani Najafabadi, Kexing Lyu, Yao Xu, Ying Xin, Anna Schwendeman, Max S Wicha, Alfred E Chang, Qiao Li, James J Moon

Journal: J Control Release

PubMed ID: 36206945

Doi: 10.1016/j.jconrel.2022.09.061

Products & Services: Peptide Synthesis

Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library

Authors: Devan J Shell, Justin M Rectenwald, Peter H Buttery, Rebecca L Johnson, Caroline A Foley, Shiva K R Guduru, Mélanie Uguen, Juanita Sanchez Rubiano, Xindi Zhang, Fengling Li, Jacqueline L Norris-Drouin, Matthew Axtman, P Brian Hardy, Masoud Vedadi, Stephen V Frye, Lindsey I James, Kenneth H Pearce

Journal: SLAS Discov

PubMed ID: 36272689

Doi: 10.1016/j.slasd.2022.10.003

Products & Services: Recombinant Proteins

Energy landscape reshaped by strain-specific mutations underlies epistasis in NS1 evolution of influenza A virus

Authors: Iktae Kim, Alyssa Dubrow, Bryan Zuniga, Baoyu Zhao, Noah Sherer, Abhishek Bastiray, Pingwei Li, Jae-Hyun Cho

Journal: Nat Commun

PubMed ID: 36182933

Doi: 10.1038/s41467-022-33554-9

Products & Services: Protein and Antibody Isolation

GITRL impairs the immunosuppressive function of MDSCs via PTEN-mediated signaling pathway in experimental Sjögren syndrome

Authors: Jie Tian, Beibei Zhang, Qingfang Yuan, Xueqing Sun, Na Peng, Bo Zhu, Chang Liu, Xiaoran Wang, Man Han, Meng Cao, Fan Xiao, Shengjun Wang, Ke Rui, Liwei Lu

Journal: Inflamm Res

PubMed ID: 36301339

Doi: 10.1007/s00011-022-01660-5

Products & Services: Protein and Antibody Isolation

An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation

Authors: Merve Avar, Daniel Heinzer, Alana M Thackray, Yingjun Liu, Marian Hruska-Plochan, Stefano Sellitto, Elke Schaper, Daniel P Pease, Jiang-An Yin, Asvin Kk Lakkaraju, Marc Emmenegger, Marco Losa, Andra Chincisan, Simone Hornemann, Magdalini Polymenidou, Raymond Bujdoso, Adriano Aguzzi

Journal: EMBO J

PubMed ID: 36254605

Doi: 10.15252/embj.2022112338

Products & Services: Mammalian Expression

Priming conditions shape breadth of neutralizing antibody responses to sarbecoviruses

Authors: Janice Zhirong Jia, Chee Wah Tan, Samuel M S Cheng, Haogao Gu, Aileen Ying Yan Yeoh, Chris Ka Pun Mok, Yanqun Wang, Jincun Zhao, Nancy H L Leung, Benjamin J Cowling, Leo L M Poon, David S C Hui, Linfa Wang, Malik Peiris, Sophie A Valkenburg

Journal: Nat Commun

PubMed ID: 36271047

Doi: 10.1038/s41467-022-34038-6

Products & Services: Mammalian Expression

Inhibition of Glypican-3 Cleavage Results in Reduced Cell Proliferation in a Liver Cancer Cell Line

Authors: Emily J Schepers, Charissa Lake, Kathryn Glaser, Alexander J Bondoc

Journal: J Surg Res

PubMed ID: 36272230

Doi: 10.1016/j.jss.2022.09.011

Products & Services: Gene Fragments

Macromolecular crowding amplifies allosteric regulation of T-Cell Protein Tyrosine Phosphatase

Authors: May Thwe Tun, Shen Yang, Fabio Luis Forti, Eugenio Santelli, Nunzio Bottini

Journal: J Biol Chem

PubMed ID: 36328244

Doi: 10.1016/j.jbc.2022.102655

Products & Services: Plasmid DNA Preparation

The large plasmid carried class 1 integrons mediated multidrug resistance of foodborne Indiana

Authors: Xuefeng Wang, Tian Wang, Mengjiao Guo, Chengcheng Zhang, Zongyi Bo, Yantao Wu, Guoxiang Chao

Journal: Front Microbiol

PubMed ID: 36312970

Doi: 10.3389/fmicb.2022.991326

Products & Services: Custom DNA/RNA Oligos

Multifunctional chemical inhibitors of the florigen activation complex discovered by structure-based high-throughput screening

Authors: Ken-Ichiro Taoka, Ikumi Kawahara, Shoko Shinya, Ken-Ichi Harada, Eiki Yamashita, Zenpei Shimatani, Kyoko Furuita, Tomoaki Muranaka, Tokitaka Oyama, Rie Terada, Atsushi Nakagawa, Toshimichi Fujiwara, Hiroyuki Tsuji, Chojiro Kojima

Journal: Plant J

PubMed ID: 36288411

Doi: 10.1111/tpj.16008

Products & Services: Peptide Synthesis