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A time-resolved, multi-symbol molecular recorder via sequential genome editing

Authors: Junhong Choi, Wei Chen, Anna Minkina, Florence M Chardon, Chase C Suiter, Samuel G Regalado, Silvia Domcke, Nobuhiko Hamazaki, Choli Lee, Beth Martin, Riza M Daza, Jay Shendure

Journal: Nature

PubMed ID: 35794474

Doi: 10.1038/s41586-022-04922-8

Products & Services: CRISPR KI Templates

Pharmacokinetic Characteristics, Safety, and Tolerability of Telitacicept, an Injectable Recombinant Human B-Lymphocyte Stimulating Factor Receptor-Antibody Fusion Protein, in Healthy Chinese Subjects

Authors: Jing Xie, Xiaoyun Fan, Yue Su, Huan Zhou, Shugang Cao, Xingyu Zhu, Minhui Zhu, Cuixia He, Ying Wang, Ling Fan, Qin Ge, Juan Zhu, Bingyan Liu, Xiao Chen, Yunqiu Xie, Ling Ma, Yuanyuan Liu, Juan Chen, Huaxue Wang, Zhijun Li

Journal: Clin Pharmacol Drug Dev

PubMed ID: 35844038

Doi: 10.1002/cpdd.1136

Products & Services: Mammalian Expression

Orphan nuclear receptor NUR77 relieves insulin resistance in HTR-8/SVneo trophoblast cells through activation of autophagy and insulin signaling

Authors: Ling Li, Yu Bai, Runyu Du, Lei Tang, Ling Li

Journal: J Physiol Biochem

PubMed ID: 35902547

Doi: 10.1007/s13105-022-00901-9

Products & Services: Protein and Antibody Isolation

Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter

Authors: Deepthi Joseph, Smruti Ranjan Nayak, Aravind Penmatsa

Journal: EMBO J

PubMed ID: 35796008

Doi: 10.15252/embj.2022110735

Products & Services: Gene Synthesis

Transcriptional response to VZV infection is modulated by RNA polymerase III in lung epithelial cell lines

Authors: Brianna M Doratt, Elizabeth Vance, Delphine C Malherbe, Mark T W Ebbert, Ilhem Messaoudi

Journal: Front Cell Infect Microbiol

PubMed ID: 35959363

Doi: 10.3389/fcimb.2022.943587

Products & Services: Protein and Antibody Isolation

A recombinant VSV-vectored vaccine rapidly protects nonhuman primates against heterologous lethal Lassa fever

Authors: Robert W Cross, Courtney Woolsey, Abhishek N Prasad, Viktoriya Borisevich, Krystle N Agans, Daniel J Deer, Joan B Geisbert, Natalie S Dobias, Karla A Fenton, Thomas W Geisbert

Journal: Cell Rep

PubMed ID: 35858566

Doi: 10.1016/j.celrep.2022.111094

Products & Services: Peptide Synthesis

SARS-CoV-2 Delta spike protein enhances the viral fusogenicity and inflammatory cytokine production

Authors: Zhujun Ao, Maggie Jing Ouyang, Titus Abiola Olukitibi, Xiaojian Yao

Journal: iScience

PubMed ID: 35854977

Doi: 10.1016/j.isci.2022.104759

Products & Services: Plasmid DNA Preparation

Stitchr: stitching coding TCR nucleotide sequences from V/J/CDR3 information

Authors: James M Heather, Matthew J Spindler, Marta Herrero Alonso, Yifang Ivana Shui, David G Millar, David S Johnson, Mark Cobbold, Aaron N Hata

Journal: Nucleic Acids Res

PubMed ID: 35325179

Doi: 10.1093/nar/gkac190

Products & Services: Protein and Antibody Isolation

A Retinol Derivative Inhibits SARS-CoV-2 Infection by Interrupting Spike-Mediated Cellular Entry

Authors: Liangqin Tong, Lin Wang, Shumin Liao, Xiaoping Xiao, Jing Qu, Chunli Wu, Yibin Zhu, Wanbo Tai, Yanhong Huang, Penghua Wang, Liang Li, Renli Zhang, Ye Xiang, Gong Cheng

Journal: MBio

PubMed ID: 35862773

Doi: 10.1128/mbio.01485-22

Products & Services: ELISA Kits

A biepitope, adjuvant-free, self-assembled influenza nanovaccine provides cross-protection against H3N2 and H1N1 viruses in mice

Authors: Yongbo Qiao, YaXin Zhang, Jie Chen, Shenghui Jin, Yaming Shan

Journal: Nano Res

PubMed ID: 35911479

Doi: 10.1007/s12274-022-4482-4

Products & Services: Plasmid DNA Preparation