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WTAP resists cholestatic liver injury by m6A-IGF2BP1-dependent regulation of the nuclear receptor FXR

Authors: Guomin Ju, Tong Wu, Yu Wu, Xueyu Zhou, Yang Yang, Xiangwen Meng, Cheng Jin, Hui Chen, Ke Sun, Ming Yu, Qinfen Xie, Shusen Zheng, Jian Wu, Chuanhui Peng

Journal: GUT

PubMed ID: 42919657

Doi: 10.1136/gutjnl-2025-337845

Products & Services: Protein Electrophoresis and Western

Aromaticity at spike position 456 affects functional immunogenicity of SARS-CoV-2 Omicron variant receptor-binding domain

Authors: Dandan Peng, Zimin Chen, Minyang Fu, Weiqi Hong, Mengzhe Dai, Hao Zeng, Sheng Lin, Hong Lei, Jingyun Yang, Jie Shi, Xiya Huang, Chunjun Ye, Furong Qin, Yu Zhang, Ying Hao, Binhan Wang, Wenyan Ren, Li Chen, Jian Liu, Aqu Alu, Yishan Lu, Xinyi Du, Jiong Li, Huashan Shi, Yuquan Wei, Yi Chen, Shuaiyao Lu, Cai He, Guangwen Lu, Xiawei Wei

Journal: Signal transduction and targeted therapy

PubMed ID: 42957648

Doi: 10.1038/s41392-026-02939-3

Products & Services: Peptide Library Services

Tryptoline stereoprobe elaboration identifies inhibitors of the GRPEL1–HSPA9 complex

Authors: Rachel E Hayward, Raymond F Berkeley, Zijian Gao, Maximilian Garhammer, Marc A Morizono, Evert Njomen, Haoxin Li, Kristen E DeMeester, Victor Cociorva, Mark A Herzik Jr, F Ulrich Hartl, Bruno Melillo, Benjamin F Cravatt

Journal: Nature Chemical Biology

PubMed ID: 42888267

Doi: 10.1038/s41589-026-02348-1

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Chromatin interaction landscape of epimorphic regeneration in teleost fish

Authors: Xiaohui Jia, Xianglei Zhang, Weifeng Lin, Tengfei Ren, Shiqi Liu, Yufei Lou, Wei Wang

Journal: Science advences

PubMed ID: 42853912

Doi: 10.1126/sciadv.aeh2087

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tRNA dosage regulates lineage dependency and resistance in prostate cancer

Authors: Yeon Soo Kim, Sonali Arora, Dave Young, Ava Tsou, Amy Shiuan, Cynthia L Wladyka, Dmytro Rudoy, Jin Yeong Kim, Jennifer A Waters, Samantha L Schuster, Ilsa M Coleman, Mridu Kapur, Marek Sobczyk, Christopher D Katanski, Amin M Bayat Tork, Wen Zhang, Peter S Nelson, Gavin Ha, Michael C Haffner, Eva Corey, Colm Morrissey, Yuzhuo Wang, Arvind R Subramaniam, John K Lee, Susan L Ackerman, Tao Pan, Andrew C Hsieh

Journal: Nature

PubMed ID: 42844465

Doi: 10.1038/s41586-026-11153-8

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PTPRS mediates invasion of tetanus neurotoxin into the central nervous system

Authors: Pengsheng Chen, Huan Wang, John Manion, Jonas Zähringer, Junjie Liang, Aisha Mohammed, Leo Zhao, Jie Zhang, Yuankai Wang, Kang Wang, Pyung-Gang Lee, Geoffrey Masuyer, Karla J F Satchell, Joseph S Brunzelle, Taekjip Ha, Pål Stenmark, Min Dong

Journal: Cell

PubMed ID: 42869022

Doi: 10.1016/j.cell.2026.09.026

Host cell traversal by Plasmodium parasites drives sterilizing T cell-mediated immunity following immunization

Authors: Ana Rodrigues, António M Mendes, Rute Gonçalves, Helena Nunes-Cabaço, Sofia Marques, Nuno Valente-Leal, Daniel Gomes da Costa, Cristina Ferreira, Marc Veldhoen, Miguel Prudêncio, Maria M Mota, Ângelo Ferreira Chora

Journal: Nature Microbiology

PubMed ID: 42816581

Doi: 10.1038/s41564-026-02477-2.

Products & Services: Peptide Synthesis

Molecular Programming of Steric Tags for Controlled Nanopore Translocation toward Precision Clinical Diagnostic Assistance

Authors: Heng Liu, Shijun Lin, Minglun Li, Hao Fang, Zhicheng Zhang, Ruwei Wei, Yan Zhang, Jun Dai, Tao Liu, Fan Xia, Xiaoding Lou

Journal: Journal of the American Chemical Society

Doi: doi.org/10.1021/jacs.6c15448

Products & Services: Peptide Synthesis

Dense RNA motif modifications enable robust in vivo prime editing and enhance efficiencies of diverse editing systems

Authors: Xinlin Lei, Didi Chen, Kun Zhang, Xiyu Liu, Qiubing Chen, Yizhou Zhang, Ruijin Ji, Jicheng Zhu, Qingyi Zhang, Ying Zhang, Hao Yin

Journal: nature biomedical engineering

PubMed ID: 42728339

Doi: 10.1038/s41551-026-01787-4

Products & Services: Gene Synthesis

Self-Assembled Dual-Drug Nanoparticles for Tumor-Targeted Delivery and Enhanced Antitumor Chemo-Immunotherapy

Authors: Li-Wen Hu, Bo-Jia Li, Hao Zhou, Rui-Qi Zhao, Fang-Bing Liu, Jia-Hao Liu, Xiao-Yang Zhang, Wei-Hai Chen, Xian-Zheng Zhang

Journal: Advanced Functional Materials

Doi: 10.1002/adfm.78916

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