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Metabolic and immunomodulatory control of type 2 diabetes via generating cellular itaconate reservoirs by inflammatory-targeting gene-therapy nanovesicles

Authors: An Lao, Weiqi Li, Yiting Sun, Yuting Cao, Yu Zhuang, Jianyong Wu, Dejian Li, Kaili Lin, Jing Mao, Jiaqiang Liu

Journal: Trends in biotechnology

PubMed ID: 40925799

Doi: 10.1016/j.tibtech.2025.07.025

Products & Services: Proteins, Expression, Isolation and Analysis

A reproducible hybrid membrane for in situ analysis of cell secretions with a wide size range

Authors: Zixuan Chen, Yafeng Wu, Zhaoyan Tian, Zhaohan Wang, Weiwei Liu, Songqin Liu

Journal: Chinese Chemical Letters

Doi: 10.1016/j.cclet.2025.110917

Products & Services: Recombinant Proteins

A Porcine Monoclonal Antibody Targeting a Conserved GP4 Epitope Protects Against In Vivo Infection via the Induction of Broad-Spectrum PRRSV Neutralization

Authors: Xu Chen, Jiakai Zhao, Pinpin Ji, Xiaoxuan Li, Hui Niu, Dian Jiao, Lu Zhang, Qianyi Zhu, Xinyu Liu, Julian A Hiscox, James P Stewart, Yani Sun, Qin Zhao

Journal: Advanced Science

PubMed ID: 40919718

Doi: 10.1002/advs.202508875

Products & Services: Molecular Biology Reagents

Planthopper protein Nlsp5 is essential for salivary sheath formation and acts as a HAMP inducing plant resistance to insects

Authors: Liangxuan Qi, Jing Li, Han Wang, Shuai Li, Lei Yang, Jichao Fang, Rui Ji

Journal: Plant Biotechnology Journal

PubMed ID: 40546084

Doi: DOI10.1111/pbi.70223

Products & Services: Polyclonal Antibody Services

Dynamic U2AF cycling defines two phases of cotranscriptional pre-mRNA splicing

Authors: Changwei Shao, Yajing Hao, Li Jiang, Dong Wang, Rui Wang, Yuanjun Li, Hui Wang, Yaping Ge, Rui Bai, Xiangjuan Du, Xizi Chen, Tan Wu, Lan-Tao Gou, Ruixue Wan, Yanhui Xu, Xiong Ji, Xiang-Dong Fu

Journal: Science

PubMed ID: 40997183

Doi: 10.1126/science.adj9141

Products & Services: Proteins, Expression, Isolation and Analysis

Targeted Blockage of Pathological Extracellular Vesicles and Particles From Fibroblast-Like Synoviocytes for Osteoarthritis Relief: Proteomic Analysis and Cellular Effect

Authors: Bin Liu, Yansi Xian, Tao Shen, Yu Ben, Wenshu Wu, Yong Shi, Xueying An, Rui Peng, Wentian Gao, Wang Gong, Xiang Chen, Baosheng Guo, Qing Jiang

Journal: Journal of extracellular vesicles

PubMed ID: 40919882

Doi: 10.1002/jev2.70162

Products & Services: Proteins, Expression, Isolation and Analysis

A broadly neutralizing antibody recognizes a unique epitope with a signature motif common across coronaviruses

Authors: Lei Yan, Fulian Wang, Michelle Hill, Juliane Brun, Ze Liang, Xinyu Shi, Liangminghui Zhang, Xiuxiu He, Yu Li, Qianping Huang, Xuxue Dong, Huanzhen Liu, Yi Zhang, Lili Liu, Raymond A Dwek, Nicole Zitzmann, Aibin Liang, Guang Yang

Journal: Nature Communications

PubMed ID: 40813592

Doi: doi.org/10.1038/s41467-025-63101-1

Products & Services: Peptide Synthesis

Biochemical Consequences of a Leucine-to-Cysteine Clamp Substitution in Lipoxygenases

Authors: Samuel G Hill, Katherine DeFeo, Adam R Offenbacher

Journal: Biomolecules

PubMed ID: 40867598

Doi: 10.3390/biom15081153

Products & Services: Gene Synthesis

Chimeric virus-like particles replacing the loop on the surface of VP60 from rabbit hemorrhagic disease virus (RHDV) provide protection against two serotypes of RHDV

Authors: Wangzhen Xiang, Beibei Pan, Yuxin Hao, Fei Wang, Jialu Bao, Shanchun Su, Shuai Qie, Chungang Pan, Zhen Cao, Xinyue Liu, Jiajun Wu, Tong Zhang, Xinyan Zhai, Fei Yang, Peng Qi, Jiangtao Wang, Jin Xiao, Xin Guo

Journal: Vaccine

PubMed ID: 40614613

Doi: 10.1016/j.vaccine.2025.127427

Products & Services: Gene Synthesis

ANovelDeNovoBiosyntheticPathwayforEfficientSynthesisof6′ SialyllactoseinEscherichiacoli

Authors: Manxiang Zhu,Hongzhi Xia, Xianhao Xu, Yanfeng Liu, Guocheng Du,XuKueqin Lv, Long Liu, Shixiu Cui, Jianghua Li, and Yingyue Li

Journal: Synthetic Biology

Doi: 10.1021/acssynbio.5c00437

Products & Services: Gene Synthesis