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Screening membraneless organelle participants with machine-learning models that integrate multimodal features

Authors: Zhaoming Chen, Chao Hou, Liang Wang, Chunyu Yu, Taoyu Chen, Boyan Shen, Yaoyao Hou, Pilong Li, Tingting Li

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35687670

Doi: 10.1073/pnas.2115369119

Products & Services: Protein and Antibody Isolation

Characterization, expression and function of the pyrokinins (PKs) in the giant freshwater prawn, Macrobrachium rosenbergii

Authors: Tipsuda Thongbuakaew, Sirirak Mukem, Arada Chaiyamoon, Kanjana Khornchatri, Thanapong Kruangkum, Scott F Cummins, Prasert Sobhon

Journal: J Exp Biol

PubMed ID: 35578905

Doi: 10.1242/jeb.243742

Products & Services: Peptide Synthesis

Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition

Authors: Eric T Baldwin, Matthias Götte, Egor P Tchesnokov, Eddy Arnold, Margit Hagel, Charles Nichols, Pam Dossang, Marieke Lamers, Paul Wan, Stefan Steinbacher, Donna L Romero

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35771941

Doi: 10.1073/pnas.2200260119

Products & Services: Codon Optimization

TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules

Authors: Andrew C McShan, Christine A Devlin, Georgia F Papadaki, Yi Sun, Adam I Green, Giora I Morozov, George M Burslem, Erik Procko, Nikolaos G Sgourakis

Journal: Nat Chem Biol

PubMed ID: 35725941

Doi: 10.1038/s41589-022-01049-9

Products & Services: Catalog Peptides

Tailored protein-conjugated DNA nanoplatform for synergistic cancer therapy

Authors: Dingkang Liu, Ye Chen, Qun Wang, Yue Ji, Lichen Bao, Wenbing Yao, Xiangdong Gao, Jun Yin

Journal: Journal of controlled release

PubMed ID: 35452765

Doi: 10.1016/j.jconrel.2022.04.022

Products & Services: Gene Synthesis

Structural and mechanistic insights into the inhibition of type I-F CRISPR-Cas system by anti-CRISPR protein AcrIF23

Authors: Junhui Ren, Hao Wang, Lingguang Yang, Feixue Li, Yao Wu, Zhipu Luo, Zeliang Chen, Yi Zhang, Yue Feng

Journal: J Biol Chem

PubMed ID: 35697070

Doi: 10.1016/j.jbc.2022.102124

Products & Services: Mutant Libraries

Immunoinformatics Aided Design and Validation of a Cross-Reactive Peptide Based Multi-Epitope Vaccine Targeting Multiple Serotypes of Dengue Virus

Authors: Vikas Kaushik, Sunil Krishnan G, Lovi Raj Gupta, Utkarsh Kalra, Abdul Rajjak Shaikh, Luigi Cavallo, Mohit Chawla

Journal: Front Immunol

PubMed ID: 35799781

Doi: 10.3389/fimmu.2022.865180

Products & Services: Catalog Peptides

Recombinant Carrying Endostatin Protein Alleviates Dextran Sodium Sulfate-Induced Colitis and Colon Cancer in Rats

Authors: Zhiqian Bi, Enqing Cui, Yingying Yao, Xiaoyao Chang, Xiaoyang Wang, Yuhui Zhang, Gen-Xing Xu, Hongqin Zhuang, Zi-Chun Hua

Journal: Front Microbiol

PubMed ID: 35847065

Doi: 10.3389/fmicb.2022.927277

Products & Services: Mammalian Expression

CRISPR/CasRx-Mediated RNA Knockdown Reveals That ACE2 Is Involved in the Regulation of Oligodendroglial Cell Morphological Differentiation

Authors: Yukino Kato, Kenji Tago, Shoya Fukatsu, Miyu Okabe, Remina Shirai, Hiroaki Oizumi, Katsuya Ohbuchi, Masahiro Yamamoto, Kazushige Mizoguchi, Yuki Miyamoto, Junji Yamauchi

Journal: Noncoding RNA

PubMed ID: 35736639

Doi: 10.3390/ncrna8030042

Products & Services: Custom Vector Construction

Long Intergenic Noncoding RNA MIAT as a Regulator of Human Th17 Cell Differentiation

Authors: Mohd Moin Khan, Meraj Hasan Khan, Ubaid Ullah Kalim, Sofia Khan, Sini Junttila, Niklas Paulin, Lingjia Kong, Omid Rasool, Laura L Elo, Riitta Lahesmaa

Journal: Front Immunol

PubMed ID: 35784351

Doi: 10.3389/fimmu.2022.856762

Products & Services: Plasmid DNA Preparation