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Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment

Authors: Robin M Hallett, Ester Bonfill-Teixidor, Raffaella Iurlaro, Alexandra Arias, Swetha Raman, Peter Bayliss, Olga Egorova, Almudena Neva-Alejo, Aj Robert McGray, Esther Lau, Alexandre Bosch, Melissa Beilschmidt, Dorothea Maetzel, Johan Fransson, Isabel Huber-Ruano, Judit Anido, Jean-Philippe Julien, Patricia Giblin, Joan Seoane

Journal: Clin Cancer Res

PubMed ID: 36441800

Doi: 10.1158/1078-0432.CCR-21-1888

Products & Services: Peptide Synthesis

Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease

Authors: Raaj S Mehta, Jared R Mayers, Yancong Zhang, Amrisha Bhosle, Nathaniel R Glasser, Long H Nguyen, Wenjie Ma, Sena Bae, Tobyn Branck, Kijun Song, Luke Sebastian, Julian Avila Pacheco, Hyuk-Soo Seo, Clary Clish, Sirano Dhe-Paganon, Ashwin N Ananthakrishnan, Eric A Franzosa, Emily P Balskus, Andrew T Chan, Curtis Huttenhower

Journal: Nat Med

PubMed ID: 36823301

Doi: 10.1038/s41591-023-02217-7

Products & Services: Protein and Antibody Isolation

Exocytic machineries differentially control mediator release from allergen-triggered RBL-2H3 cells

Authors: Pratikshya Adhikari, Tolulope E Ayo, John C Vines, Shuzo Sugita, Hao Xu

Journal: Inflamm Res

PubMed ID: 36725743

Doi: 10.1007/s00011-023-01698-z

Products & Services: Protein and Antibody Isolation

Transplantation of A2 type astrocytes promotes neural repair and remyelination after spinal cord injury

Authors: Jie Chang, Zhanyang Qian, Binyu Wang, Jiang Cao, Sheng Zhang, Fan Jiang, Renyi Kong, Xiao Yu, Xiaojian Cao, Lei Yang, Hongtao Chen

Journal: Cell Commun Signal

PubMed ID: 36797790

Doi: 10.1186/s12964-022-01036-6

Products & Services: Protein and Antibody Isolation

Generation of TGFβR2(-1) neoantigen-specific HLA-DR4-restricted T cell receptors for cancer therapy

Authors: Natalia Plewa, Lucia Poncette, Thomas Blankenstein

Journal: J Immunother Cancer

PubMed ID: 36822673

Doi: 10.1136/jitc-2022-006001

Products & Services: Peptide Synthesis

Mechanism of inhibition of CRISPR-Cas9 by anti-CRISPR protein AcrIIC1

Authors: Yalan Zhu, Sen Yin, Zhao Li

Journal: Biochem Biophys Res Commun

PubMed ID: 36878037

Doi: 10.1016/j.bbrc.2023.02.065

Products & Services: Molecular Biology Reagents

Function of the bacteriophage P2 baseplate central spike Apex domain in the infection process

Authors: John-Mark Miller, Ekaterina S Knyazhanskaya, Sergii A Buth, Nikolai S Prokhorov, Petr G Leiman

Journal: biorxiv

PubMed ID: 36865152

Doi: 10.1101/2023.02.25.529910

Products & Services: Protein and Antibody Isolation

A novel binary pesticidal protein from Chryseobacterium arthrosphaerae controls western corn rootworm by a different mode of action to existing commercial pesticidal proteins

Authors: Rania Jabeur, Virginie Guyon, Szabolcs Toth, Adriano E Pereira, Man P Huynh, Zakia Selmani, Erin Boland, Mickael Bosio, Laurent Beuf, Pete Clark, David Vallenet, Wafa Achouak, Carine Audiffrin, François Torney, Wyatt Paul, Thierry Heulin, Bruce E Hibbard, Stefan Toepfer, Christophe Sallaud

Journal: PLoS ONE

PubMed ID: 36800363

Doi: 10.1371/journal.pone.0267220

Products & Services: Protein and Antibody Isolation

pH-Sensitive and Biodegradable Mn3(PO4)2·3H2O Nanoparticles as an Adjuvant of Protein-Based Bivalent COVID-19 Vaccine to Induce Potent and Broad-Spectrum Immunity

Authors: Shi-Hao Zhou,‡Ru-Yan Zhang,Zi-Wei You, Yong-Ke Zou, Yu Wen, Jian Wang, Dong Ding, Miao-Miao Bian, Zhi-Ming Zhang, Hong Yuan, Guang-Fu Yang, and Jun Guo

Journal: ACS Applied Materials & Interfaces

Doi: 10.1021/acsami.2c19736

Products & Services: Recombinant Proteins

ACE2 binding and antibody evasion in enhanced transmissibility of XBB15

Authors: Can Yue, Weiliang Song, Lei Wang, Fanchong Jian, Xiaosu Chen, Fei Gao, Zhongyang Shen, Youchun Wang, Xiangxi Wang, Yunlong Cao

Journal: Lancet Infect Dis

PubMed ID: 36746173

Doi: 10.1016/S1473-3099(23)00010-5

Products & Services: Protein and Antibody Isolation