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Autoinhibitory structure of preligand association state implicates a new strategy to attain effective DR5 receptor activation

Authors: Gang Du, Linlin Zhao, Yumei Zheng, Anissa Belfetmi, Tiantian Cai, Boying Xu, Karen Heyninck, Kim Van Den Heede, Marie-Ange Buyse, Pietro Fontana, Michael Bowman, Lih-Ling Lin, Hao Wu, James Jeiwen Chou

Journal: Cell Res

PubMed ID: 36604598

Doi: 10.1038/s41422-022-00755-2

Products & Services: Plasmid DNA Preparation

Monosynaptic restriction of the anterograde herpes simplex virus strain H129 for neural circuit tracing

Authors: Kyle B Fischer, Hannah K Collins, Yan Pang, Dheeraj S Roy, Ying Zhang, Guoping Feng, Shu-Jing Li, Adam Kepecs, Edward M Callaway

Journal: J Comp Neurol

PubMed ID: 36606699

Doi: 10.1002/cne.25451

Products & Services: Molecular Biology Reagents

Evaluation of a biotin-based surrogate virus neutralization test for detecting postvaccination antibodies against SARS-CoV-2 variants in sera

Authors: Min-Ju Ahn, Jung-Ah Kang, Su Min Hong, Kyu-Sun Lee, Dong Ho Kim, Daesub Song, Dae Gwin Jeong

Journal: Biochem Biophys Res Commun

PubMed ID: 36696754

Doi: 10.1016/j.bbrc.2023.01.052

Products & Services: Molecular Biology Reagents

Vaccination with S, an antigen guided by SARS-CoV-2 S protein evolution, protects against challenge with viral variants in mice

Authors: Yongliang Zhao, Wenjia Ni, Simeng Liang, Lianghui Dong, Min Xiang, Zeng Cai, Danping Niu, Qiuhan Zhang, Dehe Wang, Yucheng Zheng, Zhen Zhang, Dan Zhou, Wenhua Guo, Yongbing Pan, Xiaoli Wu, Yimin Yang, Zhaofei Jing, Yongzhong Jiang, Yu Chen, Huan Yan, Yu Zhou, Ke Xu, Ke Lan

Journal: Sci Transl Med

PubMed ID: 36599007

Doi: 10.1126/scitranslmed.abo3332

Products & Services: Plasmids for SARS-CoV-2 Detection and Research

Nanocell COVID-19 vaccine triggers a novel immune response pathway producing high-affinity antibodies which neutralize all variants of concern

Authors: Steven Y Gao, Nancy B Amaro-Mugridge, Jocelyn Madrid-Weiss, Nikolina Petkovic, Natasha Vanegas, Kumar Visvanathan, Bryan R G Williams, Jennifer A MacDiarmid, Himanshu Brahmbhatt

Journal: Front Immunol

PubMed ID: 36818474

Doi: 10.3389/fimmu.2022.1038562

Products & Services: Molecular Biology Reagents

Detection and Molecular Characterization of the SARS-CoV-2 Delta Variant and the Specific Immune Response in Companion Animals in Switzerland

Authors: Evelyn Kuhlmeier, Tatjana Chan, Cecilia Valenzuela Agüí, Barbara Willi, Aline Wolfensberger, Christian Beisel, Ivan Topolsky, Niko Beerenwinkel, Tanja Stadler, Sarah Jones, Grace Tyson, Margaret J Hosie, Katja Reitt, Julia Hüttl, Marina L Meli, Regina Hofmann-Lehmann

Journal: Viruses

PubMed ID: 36680285

Doi: 10.3390/v15010245

Products & Services: Protein and Antibody Isolation

Calmodulin variants associated with congenital arrhythmia impair selectivity for ryanodine receptors

Authors: Giuditta Dal Cortivo, Valerio Marino, Silvia Bianconi, Daniele Dell'Orco

Journal: Front Mol Biosci

PubMed ID: 36685279

Doi: 10.3389/fmolb.2022.1100992

Products & Services: DNA Sequencing

Defending against SARS-CoV-2: The T cell perspective

Authors: Patricia Almendro-Vázquez, Rocío Laguna-Goya, Estela Paz-Artal

Journal: Front Immunol

PubMed ID: 36776863

Doi: 10.3389/fimmu.2023.1107803

Products & Services: Gene Synthesis

Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance

Authors: Dario Gerace, Quan Zhou, Jennifer Hyoje-Ryu Kenty, Adrian Veres, Elad Sintov, Xi Wang, Kyle R Boulanger, Hongfei Li, Douglas A Melton

Journal: Cell Rep Med

PubMed ID: 36599351

Doi: 10.1016/j.xcrm.2022.100879

Products & Services: Peptide Synthesis

Low-cost and prototype-friendly method for biocompatible encapsulation of implantable electronics with epoxy overmolding, hermetic feedthroughs and P3HT coating

Authors: Marek Novák, Jozef Rosina, Hana Bendová, Kristina Kejlová, Alena Vlková, Marian Rucki, Lada Svobodová, Robert Gürlich, Jan Hajer

Journal: Sci Rep

PubMed ID: 36717683

Doi: 10.1038/s41598-023-28699-6

Products & Services: Peptide Synthesis