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Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376

Authors: Xiao-dong Luan, Bin-xian Chen, Wei-juan Shang , Wan-chao Yin , Ye Jin , Lei-ke Zhang , H. Eric Xu and Shu-yang Zhang

Journal: Acta pharmacologica Sinica

Doi: 10.1038/s41401-022-00929-z

Products & Services: Gene Synthesis

Engineering substrate specificity of HAD phosphatases and multienzyme systems development for the thermodynamic-driven manufacturing sugars

Authors: Chaoyu Tian , Jiangang Yang , Cui Liu , Peng Chen , Tong Zhang , Yan Men , Hongwu Ma , Yuanxia Sun, Yanhe Ma

Journal: Nat Commun

PubMed ID: 35739124

Doi: doi.org/10.1038/s41467-022-31371-8

Products & Services: Gene Synthesis

WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage

Authors: Seong-Su Han , Kuo-Kuang Wen , María L García-Rubio , Marc S Wold , Andrés Aguilera , Wojciech Niedzwiedz , Yatin M Vyas

Journal: Nat Commun

PubMed ID: 35768435

Doi: 10.1038/s41467-022-31415-z.

Products & Services: Protein and Antibody Isolation

Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes

Authors: Lucy C Walters, Daniel Rozbesky, Karl Harlos, Max Quastel, Hong Sun, Sebastian Springer, Robert P Rambo, Fiyaz Mohammed, E Yvonne Jones, Andrew J McMichael, Geraldine M Gillespie

Journal: Cell Rep

PubMed ID: 35705051

Doi: 10.1016/j.celrep.2022.110959

Products & Services: Catalog Peptides

Microfluidic T Cell Selection by Cellular Avidity

Authors: Julian F Ashby, Julien Schmidt, Neelima Kc, Armand Kurum, Caroline Koch, Alexandre Harari, Li Tang, Sam H Au

Journal: Adv Healthc Mater

PubMed ID: 35657072

Doi: 10.1002/adhm.202200169

Products & Services: Catalog Peptides

Successful Preservation of Native BCR::ABL1 in Chronic Myeloid Leukemia Primary Leukocytes Reveals a Reduced Kinase Activity

Authors: Christian Boni, Massimiliano Bonifacio, Marzia Vezzalini, Luigi Scaffidi, Luisa Tomasello, Laurie L Parker, Diego Boscarino, Dino Paladin, Mauro Krampera, Claudio Sorio

Journal: Front Oncol

PubMed ID: 35756686

Doi: 10.3389/fonc.2022.904510

Products & Services: Catalog Peptides

Preclinical study of formulated recombinant nucleocapsid protein, the receptor binding domain of the spike protein, and truncated spike (S1) protein as vaccine candidates against COVID-19 in animal models

Authors: Shahram Nazarian, Gholamreza Olad, Raziyeh Abdolhamidi, Mohammad Javad Motamedi, Rouhollah Kazemi, Emad Kordbacheh, Alireza Felagari, Hanieh Olad, Ali Ahmadi, Alireza Bahiraee, Parisa Farahani, Leila Haghighi, Faezeh Hassani, Vahideh Hajhassan, Mona Nadi, Abdolkarim Sheikhi, Jafar Salimian, Jafar Amani

Journal: Mol Immunol

PubMed ID: 35802999

Doi: 10.1016/j.molimm.2022.06.007

Products & Services: PCR Cloning and Subcloning

Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells

Authors: Daniel A Michelson, Koji Hase, Tsuneyasu Kaisho, Christophe Benoist, Diane Mathis

Journal: Cell

PubMed ID: 35714609

Doi: 10.1016/j.cell.2022.05.018

Products & Services: Catalog Peptides

Novel Mutations Associated With Epilepsy and Impacts on Neuronal Excitability

Authors: Changning Xie, Fangyun Liu, Hailan He, Fang He, Leilei Mao, Xiaole Wang, Fei Yin, Jing Peng

Journal: Front Mol Neurosci

PubMed ID: 35845605

Doi: 10.3389/fnmol.2022.870182

Products & Services: Plasmid DNA Preparation

EXPLICIT-Kinase: A gene expression predictor for dissecting the functions of the Arabidopsis kinome

Authors: Yuming Peng, Wanzhu Zuo, Hui Zhou, Fenfen Miao, Yu Zhang, Yue Qin, Yi Liu, Yu Long, Shisong Ma

Journal: J Integr Plant Biol

PubMed ID: 35446465

Doi: 10.1111/jipb.13267

Products & Services: Catalog Antibodies