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Single-cell RNA sequencing and PANDORA-seq reveal the pivotal role of piRNA in heat stress-induced testicular injury

Authors: Mailin Gan, Jianfeng Ma, Yuhang Lei, Yiting Yang, Yuheng Pan, Shuang Wu, Siyu Chen, Jiaxin Li, Linyuan Shen, Li Zhu

Journal: International Journal of Biological Macromolecules

PubMed ID: 40609925

Doi: 10.1016/j.ijbiomac.2025.145674

Products & Services: Protein and Antibody Isolation

The evolution of eukaryotic linear motifs governing the function of androgen receptor from fish to Homo sapiens

Authors: Antonella Falconieri, Giulia Boarolo, Chiara Boschelle, Giovanni Spagnolli, Caterina Marchioretti, Emanuela Zuccaro, Isabella Palazzolo, Laura Tosatto, Adham Kamaleldeen Omara Hegazy, Jessica Rosati, Kenneth Fischbeck, Manuela Basso, Hans Christoph Liedtke, Ivan Gomez-Mestre, Luisa Dalla Valle, Emiliano Biasini, Pietro Faccioli, Alessandro Grapputo, Maria Pennuto

Journal: Nucleic acids research

PubMed ID: 40682815

Doi: 10.1093/nar/gkaf688

Products & Services: Custom Vector Construction

Visualization of a multi-turnover Cas9 after product release

Authors: Kaitlyn A. Kiernan & David W. Taylor

Journal: Nature Communications

PubMed ID: 40593576

Doi: 10.1038/s41467-025-60668-7

Products & Services: Synthetic Guide RNA

Molecular architecture and catalytic mechanism of human glycogen debranching enzyme

Authors: Huiyi Guan, Huan Chen, He Geng, Ruifang Ma, Zhongmin Liu, Yong Wang, Yifang Chen, Kaige Yan

Journal: Nature Communications

PubMed ID: 40593796

Doi: 10.1038/s41467-025-61077-6

Products & Services: Protein and Antibody Isolation

Single-domain antibodies directed against hemagglutinin and neuraminidase protect against influenza B viruses

Authors: Arne Matthys, Jan Felix, Joao Paulo Portela Catani, Kenny Roose, Wim Nerinckx, Benthe Van Buyten, Daria Fijalkowska, Nico Callewaert, Savvas N Savvides, Xavier Saelens

Journal: Nature Communications

PubMed ID: 40593518

Doi: 10.1038/s41467-025-60232-3

Products & Services: Catalog Antibodies

Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery

Authors: Amanda X Y Chen, Kah Min Yap, Joelle S Kim, Kevin Sek, Yu-Kuan Huang, Phoebe A Dunbar, Volker Wiebking, Jesse D Armitage, Isabelle Munoz, Kirsten L Todd, Emily B Derrick, Dat Nguyen, Junming Tong, Cheok Weng Chan, Thang X Hoang, Katherine M Audsley, Marit J van Elsas, Jim Middelburg, Joel N Lee, Maria N de Menezes, Thomas J Cole, Jasmine Li, Christina Scheffler, Andrew M Scott, Laura K Mackay, Jason Waithman, Jane Oliaro, Simon J Harrison, Ian A Parish, Junyun Lai, Matthew H Porteus, Imran G House, Phillip K Darcy, Paul A Beavis

Journal: Nature

PubMed ID: 40604285

Doi: 10.1038/s41586-025-09212-7

Products & Services: PCR Cloning and Subcloning

A single main-chain hydrogen bond required to keep GABAA receptors closed

Authors: Cecilia M Borghese, Jason D Galpin, Samuel Eriksson Lidbrink, Yuxuan Zhuang, Netrang G Desai, Rebecca J Howard, Erik Lindahl, Christopher A Ahern, Marcel P Goldschen-Ohm

Journal: Nature Communications

PubMed ID: 40603861

Doi: 10.1038/s41467-025-61447-0

Products & Services: Mutagenesis Services

NXT2 is a key component of the RNA nuclear export factor complex in the human testis and essential for spermatogenesis

Authors: Ann-Kristin Dicke, Ammar Ahmedani, Lin Ma, Leonie Herrmann, Godfried W van der Heijden, Sophie A Koser, Claudia Krallmann, Oguzhan Kalyon, Miguel J Xavier, Joris A Veltman, Sabine Kliesch, Nina Neuhaus, Noora Kotaja, Frank Tüttelmann, Birgit Stallmeyer

Journal: Nature Communications

PubMed ID: 40624043

Doi: 10.1038/s41467-025-61463-0

Products & Services: PCR Cloning and Subcloning

Nucleosome spacing can fine-tune higher-order chromatin assembly

Authors: Lifeng Chen, M Julia Maristany, Stephen E Farr, Jinyue Luo, Bryan A Gibson, Lynda K Doolittle, Jorge R Espinosa, Jan Huertas, Sy Redding, Rosana Collepardo-Guevara, Michael K Rosen

Journal: Nature Communications

PubMed ID: 40628730

Doi: 10.1038/s41467-025-61482-x

Products & Services: Gene Fragments

Ion channel structure and function of the MERS coronavirus E protein

Authors: Iva Sučec, Bingqing Xia, Noah H Somberg, Yi Wang, Hyunil Jo, Shuangqu Li, Barbara Perrone, Zhaobing Gao, Mei Hong

Journal: SCIENCE ADVANCES

PubMed ID: 40632851

Doi: 10.1126/sciadv.adx1788

Products & Services: PCR Cloning and Subcloning