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Design, synthesis, and biological evaluation of novel napabucasin-melatonin hybrids as potent STAT3 inhibitors

Authors: Chong Zhang, Limin Yang, Xiaojuan Yang, Qinghe Gao, Yan Qu, Liqiang Wu

Journal: Bioorg Chem

PubMed ID: 37062104

Doi: 10.1016/j.bioorg.2023.106541

Products & Services: Molecular Biology Reagents

Discovery of Lactomodulin, a Unique Microbiome-Derived Peptide That Exhibits Dual Anti-Inflammatory and Antimicrobial Activity against Multidrug-Resistant Pathogens

Authors: Walaa K Mousa, Rose Ghemrawi, Tareq Abu-Izneid, Azza Ramadan, Farah Al-Marzooq

Journal: Int J Mol Sci

PubMed ID: 37108065

Doi: 10.3390/ijms24086901

Products & Services: Molecular Biology Reagents

Porcine Deltacoronavirus-like Particles Produced by a Single Recombinant Baculovirus Elicit Virus-Specific Immune Responses in Mice

Authors: Yangkun Liu, Xueying Han, Yaqi Qiao, Tiejun Wang, Lunguang Yao

Journal: Viruses

PubMed ID: 37243181

Doi: 10.3390/v15051095

Products & Services: Molecular Biology Reagents

Expansion of circulating stem-like CD8 T cells by adding CD122-directed IL-2 complexes to radiation and anti-PD1 therapies in mice

Authors: Kateryna Onyshchenko, Ren Luo, Elena Guffart, Simone Gaedicke, Anca-Ligia Grosu, Elke Firat, Gabriele Niedermann

Journal: Nat Commun

PubMed ID: 37045833

Doi: 10.1038/s41467-023-37825-x

Products & Services: Molecular Biology Reagents

Development and Evaluation of a Competitive Enzyme-Linked Immunosorbent Assay Based on Swine Monoclonal Antibodies for Detecting Neutralizing Antibodies against Senecavirus A

Authors: Xueqing Ma, Jiaxin Huang, Kun Li, Kailu Ding, Yuanfang Fu, Jing Zhang, Zhixun Zhao, Pinghua Li, Xingwen Bai, Dong Li, Xia Liu, Qiaoying Zeng, Zaixin Liu, Pu Sun, Zengjun Lu

Journal: Microbiol Spectr

PubMed ID: 37036366

Doi: 10.1128/spectrum.04599-22

Products & Services: Molecular Biology Reagents

Mellitin peptide quantification in seasonally collected crude bee venom and its anticancer effects on myelogenous K562 human leukaemia cell line

Authors: Maher Obeidat, Ihab F Al-Khraisat, Da'san M M Jaradat, Bayan Y Ghanim, Qasem M Abdallah, Duaa Abu Arqoub, Duaa Sabbah, Ola M Al-Sanabra, Tawfiq Arafat, Nidal A Qinna

Journal: BMC Complement Med Ther

PubMed ID: 37098530

Doi: 10.1186/s12906-023-03897-x

Products & Services: DNA Sequencing

A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation

Authors: Chiara Acchioni, Marta Acchioni, Flavia Mancini, Antonello Amendola, Giulia Marsili, Valentina Tirelli, Chin Piaw Gwee, Kitti Wing-Ki Chan, Silvia Sandini, Monica Bisbocci, Mohamed Mysara, Mahmoud ElHefnawi, Massimo Sanchez, Giulietta Venturi, Maria Letizia Barreca, Giuseppe Manfroni, Alberto Bresciani, Subhash G Vasudevan, Marco Sgarbanti

Journal: Virology

PubMed ID: 37060797

Doi: 10.1016/j.virol.2023.03.016

Products & Services: Gene Synthesis

Melittin derived peptide-drug conjugate, M-DM1, inhibits tumor progression and induces effector cell infiltration in melanoma by targeting M2 tumor-associated macrophages

Authors: Chanmi Jeong, Jeongdong Kim, Ik-Hwan Han, Soyoung Kim, Ilseob Choi, Hongsung Kim, Jin-Hyun Jeong, Hyunsu Bae

Journal: Front Immunol

PubMed ID: 37122692

Doi: 10.3389/fimmu.2023.1178776

Products & Services: Protein and Antibody Isolation

Structural Insights into M1 Muscarinic Acetylcholine Receptor Signaling Bias between Gαq and β-Arrestin through BRET Assays and Molecular Docking

Authors: Dongxue Wang, Yunjin Yao, Shiqi Wang, Yifei Hou, Lanxue Zhao, Hao Wang, Hongzhuan Chen, Jianrong Xu

Journal: Int J Mol Sci

PubMed ID: 37108518

Doi: 10.3390/ijms24087356

Products & Services: Protein and Antibody Isolation

A Ferritin Nanoparticle-Based Zika Virus Vaccine Candidate Induces Robust Humoral and Cellular Immune Responses and Protects Mice from Lethal Virus Challenge

Authors: Aryamav Pattnaik, Bikash R Sahoo, Lucas R Struble, Gloria E O Borgstahl, You Zhou, Rodrigo Franco, Raul G Barletta, Fernando A Osorio, Thomas M Petro, Asit K Pattnaik

Journal: Vaccines (Basel)

PubMed ID: 37112733

Doi: 10.3390/vaccines11040821

Products & Services: Gene Synthesis