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页码: 518/5234 每页显示数量

Identification of a novel ALDH1A3-selective inhibitor by a chemical probe with unrelated bioactivity: An approach to affinity-based drug target discovery

Authors: Hiroshi Kamiyama, Masayuki Miyano, Daisuke Ito, Takayuki Kimura, Koji Hagiwara, Hiroyuki Kogai, Yosuke Kaburagi, Yoshihiko Kotake, Yasutaka Takase

Journal: Chem Biol Drug Des

PubMed ID: 36334047

Doi: 10.1111/cbdd.14176

Products & Services: Plasmid DNA Preparation

Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression

Authors: Panagiotis Antoniou, Giulia Hardouin, Pierre Martinucci, Giacomo Frati, Tristan Felix, Anne Chalumeau, Letizia Fontana, Jeanne Martin, Cecile Masson, Megane Brusson, Giulia Maule, Marion Rosello, Carine Giovannangeli, Vincent Abramowski, Jean-Pierre de Villartay, Jean-Paul Concordet, Filippo Del Bene, Wassim El Nemer, Mario Amendola, Marina Cavazzana, Anna Cereseto, Oriana Romano, Annarita Miccio

Journal: Nat Commun

PubMed ID: 36333351

Doi: 10.1038/s41467-022-34493-1

Products & Services: Gene Synthesis

Association of neutrophil extracellular traps with fistula healing in patients with complex perianal fistulising Crohn's disease

Authors: Dongxing Cao, Keyu Qian, Ying Zhao, Jie Hong, Haoyan Chen, Xiaohui Wang, Nailin Yang, Cheng Zhang, Jingkai Cao, Keyu Jia, Guangyu Wu, Mingming Zhu, Jun Shen, Ye Zhang, Zhe Cui, Zheng Wang

Journal: J Crohns Colitis

PubMed ID: 36322703

Doi: 10.1093/ecco-jcc/jjac171

Products & Services: Polyclonal Antibody Services

Ectopic circSTK39 expression ameliorates hydrogen peroxide-induced human lens epithelial cell apoptosis and oxidative stress through the miR-125a-5p/ERCC6 pathway

Authors: Ming Guo, Fanfan Su, Yao Chen, Bo Su

Journal: Curr Eye Res

PubMed ID: 36322706

Doi: 10.1080/02713683.2022.2143529

Products & Services: Protein Electrophoresis and Western

Developmentally regulated mitochondrial biogenesis and cell death competence in maize pollen

Authors: Karen C Chamusco, May N Milazzo, Kanchan S Bhan, Terry L Kamps, Prestina Smith, Modupeoluwa Durojaiye, Cristina D Moreira, Maria Gallo, Christine D Chase

Journal: BMC Plant Biol

PubMed ID: 36316635

Doi: 10.1186/s12870-022-03897-y

Products & Services: Gene Synthesis

A microbial transporter of the dietary antioxidant ergothioneine

Authors: Daniel G Dumitrescu, Elizabeth M Gordon, Yekaterina Kovalyova, Anna B Seminara, Brianna Duncan-Lowey, Emily R Forster, Wen Zhou, Carmen J Booth, Aimee Shen, Philip J Kranzusch, Stavroula K Hatzios

Journal: Cell

PubMed ID: 36347253

Doi: 10.1016/j.cell.2022.10.008

Products & Services: Plasmid DNA Preparation

Structure/function studies on the activation motif of two non-mammalian Mrap1 orthologs, and observations on the phylogeny of Mrap1, including a novel characterization of an Mrap1 from the chondrostean fish, Polyodon spathula.

Authors: Robert M. Dores , Greer McKinley, Audrey Meyers, Morgan Martin and Ciaran A. Shaughnessy

Journal: Biomolecules

Doi: 10.3390/biom12111681

Products & Services: Gene Synthesis

Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes

Authors: Zeyu Jin , Li Wan , Yuqi Zhang , Xuecheng Li , Yong Cao , Haobin Liu , Shengyao Fan , Du Cao , Zhengmao Wang , Xiaobo Li , Junmin Pan , Meng-Qiu Dong , Jianping Wu , Zhen Yan

Journal: Cell

PubMed ID: 36413996

Doi: 10.1016/j.cell.2022.10.030

Products & Services: Protein and Antibody Isolation

Rice FLOURY ENDOSPERM22, encoding a pentatricopeptide repeat protein, is involved in both mitochondrial RNA splicing and editing and is crucial for endosperm development

Authors: Hang Yang , Yunlong Wang , Yunlu Tian , Xuan Teng , Zehui Lv , Jie Lei , Erchao Duan , Hui Dong , Xue Yang , Yuanyan Zhang , Yinglun Sun , Xiaoli Chen , Xiuhao Bao , Rongbo Chen , Chuanwei Gu , Yipeng Zhang , Xiaokang Jiang , Wenyu Ma , Pengcheng Zhang , Yi Ji , Yu Zhang , Yihua Wang , Jianmin Wan

Journal: J Integr Plant Biol

PubMed ID: 36333887

Doi: 10.1111/jipb.13402

Products & Services: Custom DNA/RNA Oligos

Chaperoning activity of the cyclophilin family prevents tau aggregation

Authors: Shannon E Hill , Abigail R Esquivel , Santiago Rodriguez Ospina , Lauren M Rahal , Chad A Dickey , Laura J Blair

Journal: Protein Sci

PubMed ID: 36305768

Doi: 10.1002/pro.4448

Products & Services: PCR Cloning and Subcloning