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Structural insight into bicarbonate-mediated carboxylation by human vitamin K-dependent carboxylase

Authors: Ke Wu, Zheng Wang, Deqiang Yao, Shaobai Li, Xiaozhu Wang, Yuanyuan Zhang, Mi Cao, Yafeng Shen, Shunpeng Xing, Jian Wu, Ming Lei, Pengfei Lan

Journal: Nature Communications

PubMed ID: 41290650

Doi: 10.1038/s41467-025-65488-3.

Products & Services: Protein and Antibody Isolation

Development of a cross-protective common cold coronavirus vaccine

Authors: Tanushree Dangi, Shiyi Li, Pablo Penaloza-MacMaster

Journal: Journal of Virology

PubMed ID: 41123344

Doi: 10.1128/jvi.01526-25

Products & Services: Codon Optimization

PCR-generated DNA templates enable efficient, rapid, and cost-effective mRNA synthesis

Authors: Naveen Kumar, Nicholas C Hazell, Jiani Bei, Tina Nguyen, Haitao Hu

Journal: Methods

PubMed ID: 40825451

Doi: 10.1016/j.ymeth.2025.08.007

Products & Services: PCR Cloning and Subcloning

Glycosaminoglycans activate peptidylarginine deiminase 4 by enhancing calcium affinity

Authors: Grzegorz P. Bereta， Ewa Bielecka， Karolina Marzec， Łukasz Pijanowski， Artur P. Biela， Piotr Wilk， Marta Kamińska， Jakub Nowak， Elżbieta Wątor-Wilk， Przemysław Grudnik， Dominik Kowalczyk， Joanna Kozieł， Piotr Mydel， Marcin Poręba， Tomasz Kantyka

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 41166417

Doi: doi.org/10.1073/pnas.2508369122

Products & Services: Gene Synthesis

SmallTalk: a novel small-sized fusion tag for peptide expression and purification

Authors: Atika Tariq, Nestor G Casillas-Vega, Alma Gomez-Loredo, Xristo Zarate

Journal: FEBS Open Bio

PubMed ID: 41220226

Doi: 10.1002/2211-5463.70147

Products & Services: Gene Synthesis

Structural insights into antagonist recognition by the vasopressin V2 receptor

Authors: Tianwei Zhang, Hongli Liu, Chongzhao You, Yixiao Zhang, Youwei Xu, Benxun Pan, Canrong Wu, Sanshan Jin, Yu-Ling Yin, Kai Wu, Yue Chen, Hong Sun, Yuan Si, Yangxia Tan, Wanchao Yin, H Eric Xu, Dong Guo, Yi Jiang

Journal: Nature Communications

PubMed ID: 41188237

Doi: 10.1038/s41467-025-64735-x

Products & Services: Protein and Antibody Isolation

GSH-activable and cytolytic iPep-coupled immune nanoagonist for cancer synergetic therapy

Authors: Shuangshuang Ji, Xiangxiang Xu, Ang Li, Hanjie Liu, Jiang Zhu, Hao Fei

Journal: Biomaterials

PubMed ID: 40373515

Doi: 10.1016/j.biomaterials.2025.123402

Products & Services: Peptide Synthesis

De N ovo -Designed Miniprotein Inhibits the Enzymatic Activity of the SARS-CoV 2 Main Protease

Authors: Tayn E. Lima; Emerson G. Moreira; Danilo F. Co lho; Carlos H. B. Cruz; Rafael Dhalia; Bruno H. S. Leite; L cya S. Xavier; Marta Perez Illana; Gabriel L. Wallau; Isabelle F. T. Viana; Roberto D. Lins

Journal: Journal of chemical information and modeling

PubMed ID: 41060276

Doi: 10.1021/acs.jcim.5c01708

The Sobering Sting: Oleoyl Serotonin Is a Novel Stephanoconus Snail Venom-Derived Antagonist of Cannabinoid Receptors That Counteracts Learning and Memory Deficits

Authors: Dongchen An; Guilherme Salgado Carrazoni; Ben-Hur Souto das Neves; Rudi D Hooge; Steve Peigneur; Jan Tytgat

Journal: Biomedicines

PubMed ID: 38398056

Doi: 10.3390/biomedicines12020454

Products & Services: Custom Vector Construction

In vitro characterization of the catalytic domain of human histone deacetylase 5

Authors: Christian Mammen; Fenja M. Hornung; Christian Anzenhofer; Julia Schumacher; Jens Reiners; Jingyu Li; Flaminia Mazzone; Florestan L. Bilsing; Matthias U. Kassack; Thomas Kurz; Sander H. J. Smits

Journal: Scientific REPORTS

PubMed ID: 41760657

Doi: 10.1038/s41598-026-37633-5