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Efficient Production of Epoxy-Norbornane from Norbornene by an Engineered P450 Peroxygenase

Authors: Yu Yan, Chenni Zheng, Wei Song, Jing Wu, Liang Guo, Cong Gao, Jia Liu, Xiulai Chen, Meng Zhu, Liming Liu

Journal: Chembiochem

PubMed ID: 36354378

Doi: 10.1002/cbic.202200529

Products & Services: Codon Optimization

Inhibition of autophagy reduces the rate of fluoride-induced LS8 apoptosis via regulating ATG5 and ATG7

Authors: Lin Zhao, Han Wang, Sijia Liu, Tao Xi, Liyuan Wang, Yang Li, Lu Chen, Ruan Jianping, Kristina Xiao Liang

Journal: J Biochem Mol Toxicol

PubMed ID: 36536498

Doi: 10.1002/jbt.23280

Products & Services: Gene Synthesis

A De Novo Missense Variant in TUBG2 in a Child with Global Developmental Delay, Microcephaly, Refractory Epilepsy and Perisylvian Polymicrogyria

Authors: Salini Thulasirajah, Xueqi Wang, Erick Sell, Jorge Dávila, David A Dyment, Kristin D Kernohan

Journal: Genes

PubMed ID: 36672848

Doi: 10.3390/genes14010108

Products & Services: Mutagenesis Services

Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis

Authors: Li Ma, Junfeng Wei, Yanli Zeng, Junping Liu, Erhui Xiao, Yuehua Kang, Yi Kang

Journal: Drug Deliv

PubMed ID: 35099348

Doi: 10.1080/10717544.2022.2030428

Products & Services: Protein Electrophoresis and Western

Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes

Authors: Jakub Benýšek, Michal Buša, Petra Rubešová, Jindřich Fanfrlík, Martin Lepšík, Jiří Brynda, Zuzana Matoušková, Ulrike Bartz, Martin Horn, Michael Gütschow, Michael Mareš

Journal: J Enzyme Inhib Med Chem

PubMed ID: 35144520

Doi: 10.1080/14756366.2021.2024527

Products & Services: Plasmid DNA Preparation

Suchilactone inhibits the growth of acute myeloid leukaemia by inactivating SHP2

Authors: Jingjing Wu, Yuan Deng, Xin Zhang, Jingjing Ma, Xinqi Zheng, Yue Chen

Journal: Pharm Biol

PubMed ID: 34962431

Doi: 10.1080/13880209.2021.2017467

Products & Services: Custom DNA/RNA Oligos

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

Authors: Yunlong Cao, Fanchong Jian, Jing Wang, Yuanling Yu, Weiliang Song, Ayijiang Yisimayi, Jing Wang, Ran An, Xiaosu Chen, Na Zhang, Yao Wang, Peng Wang, Lijuan Zhao, Haiyan Sun, Lingling Yu, Sijie Yang, Xiao Niu, Tianhe Xiao, Qingqing Gu, Fei Shao, Xiaohua Hao, Yanli Xu, Ronghua Jin, Zhongyang Shen, Youchun Wang, Xiaoliang Sunney Xie

Journal: Nature

PubMed ID: 36535326

Doi: 10.1038/s41586-022-05644-7

Products & Services: Protein and Antibody Isolation

Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA1 and BA2

Authors: Bingjie Hu, Jasper Fuk-Woo Chan, Huan Liu, Yuanchen Liu, Yue Chai, Jialu Shi, Huiping Shuai, Yuxin Hou, Xiner Huang, Terrence Tsz-Tai Yuen, Chaemin Yoon, Tianrenzheng Zhu, Jinjin Zhang, Wenjun Li, Anna Jinxia Zhang, Jie Zhou, Shuofeng Yuan, Bao-Zhong Zhang, Kwok-Yung Yuen, Hin Chu

Journal: Emerg Microbes Infect

PubMed ID: 36039901

Doi: 10.1080/22221751.2022.2117098

Products & Services: Plasmid DNA Preparation

SESAME-catalyzed H3T11 phosphorylation inhibits Dot1-catalyzed H3K79me3 to regulate autophagy and telomere silencing

Authors: Fei He , Qi Yu , Min Wang , Rongsha Wang , Xuanyunjing Gong , Feng Ge , Xilan Yu , Shanshan Li

Journal: Nat Commun

PubMed ID: 36473858

Doi: 10.1038/s41467-022-35182-9

Products & Services: Protein and Antibody Isolation anti-FLAG affinity gel

Reduced sensitivity of the SARS-CoV-2 Lambda variant to monoclonal antibodies and neutralizing antibodies induced by infection and vaccination

Authors: Meiyu Wang, Li Zhang, Qianqian Li, Bo Wang, Ziteng Liang, Yeqing Sun, Jianhui Nie, Jiajing Wu, Xiaodong Su, Xiaowang Qu, Yuhua Li, Youchun Wang, Weijin Huang

Journal: Emerg Microbes Infect

PubMed ID: 34818119

Doi: 10.1080/22221751.2021.2008775

Products & Services: Peptide Synthesis