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What Strengthens Protein-Protein Interactions: Analysis and Applications of Residue Correlation Networks

Authors: Ta I Hung; Yun-Jung Hsieh; Wei-Lin Lu; Kuen-Phon Wu; Chia-en A. Chang

Journal: biorxiv

PubMed ID: 36993448

Doi: 10.1101/2023.03.15.532709

Products & Services: Gene Synthesis

Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue

Authors: Colin J. Palmer; Raphael J. Bruckner; Joao A. Paulo; Lawrence Kazak; Jonathan Z. Long; Amir I. Mina; Zhaoming Deng; Katherine B. LeClair; Jessica A. Hall; Shangyu Hong; Peter-James H. Zushin; Kyle L. Smith; Steven P. Gygi; Susan Hagen; David E. Cohen; Alexander S. Banks

Journal: Molecular Metabolism

PubMed ID: 29031721

Doi: 10.1016/j.molmet.2017.07.013

Products & Services: Custom Vector Construction

Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models

Authors: Sujin Zhou, Yan Lin, Zhenggang Zhao, Yunhao Lai, Mengmeng Lu, Zishen Shao, Xinyu Mo, Yunping Mu, Zhipeng Liang, Xinxing Wang, Jingming Qu, Hua Shen, Fanghong Li, Allan Z Zhao

Journal: Cell Rep Med

PubMed ID: 37269826

Doi: 10.1016/j.xcrm.2023.101070

Products & Services: Custom Vector Construction

Engineering B cells with customized therapeutic responses using a synthetic circuit

Authors: Audrey Page, Marie Delles, Didier Nègre, Caroline Costa, Floriane Fusil, François-Loïc Cosset

Journal: Mol Ther Nucleic Acids

PubMed ID: 37359346

Doi: 10.1016/j.omtn.2023.05.024

Products & Services: PCR Cloning and Subcloning

Structural mechanism of intracellular autoregulation of zinc uptake in ZIP transporters

Authors: Changxu Pang, Jin Chai, Ping Zhu, John Shanklin, Qun Liu

Journal: Nat Commun

PubMed ID: 37296139

Doi: 10.1038/s41467-023-39010-6

Products & Services: Gene Synthesis

Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS

Authors: Yuta Adachi, Ryo Kimura, Kentaro Hirade, Shogo Yanase, Yuki Nishioka, Natsumi Kasuga, Rui Yamaguchi, Hiromichi Ebi

Journal: Nat Cancer

PubMed ID: 37277529

Doi: 10.1038/s43018-023-00575-2

Products & Services: PCR Cloning and Subcloning

GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults

Authors: Christine D Palmer, Ciaran D Scallan, Lauren D Kraemer Tardif, Melissa A Kachura, Amy R Rappaport, Daniel O Koralek, Alison Uriel, Leonid Gitlin, Joshua Klein, Matthew J Davis, Harshni Venkatraman, Meghan G Hart, Jason R Jaroslavsky, Sonia Kounlavouth, Martina Marrali, Charmaine N Nganje, Kyounghwa Bae, Tiffany Yan, Katharyn Leodones, Milana Egorova, Sue-Jean Hong, Jenchun Kuan, Silvia Grappi, Pedro Garbes, Karin Jooss, Andrew Ustianowski

Journal: Nat Commun

PubMed ID: 37280238

Doi: 10.1038/s41467-023-39053-9

Products & Services: Peptide Synthesis

Assessing the Feasibility of Employing a Combination of a Bacteriophage-Derived Endolysin and Spore Germinants to Treat Relapsing Infection

Authors: Khalid Alyahya, Les Baillie

Journal: Microorganisms

PubMed ID: 37512824

Doi: 10.3390/microorganisms11071651

Products & Services: Custom Vector Construction

Expression and characterization of recombinant IL-1Ra in Aspergillus oryzae as a system

Authors: Lena Mahmoudi Azar, Elif Karaman, Burcu Beyaz, Işılay Göktan, Alp Ertunga Eyüpoğlu, Seda Kizilel, Batu Erman, Ahmet Gül, Serdar Uysal

Journal: BMC Biotechnol

PubMed ID: 37340430

Doi: 10.1186/s12896-023-00785-7

Products & Services: Gene Synthesis

Identification of paeoniflorin from Paeonia lactiflora pall As an inhibitor of tryptophan 2,3-dioxygenase and assessment of its pharmacological effects on depressive mice

Authors: Xiaoxia Liang, Ting Su, Pingzhou Wu, Yanting Dai, Yanmin Chen, QiQi Wang, Cheng Cao, Fenglian Chen, Qing Wang, Shuling Wang

Journal: J Ethnopharmacol

PubMed ID: 37315645

Doi: 10.1016/j.jep.2023.116714

Products & Services: Protein and Antibody Isolation