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Comparative Analysis of Orthosteric and Allosteric GLP-1R Agonists' Effects on Insulin Secretion from Healthy, Diabetic, and Recovered INS-1E Pancreatic Beta Cells

Authors: Joshua Reed, Victoria Higginbotham, Stephen Bain, Venkateswarlu Kanamarlapudi

Journal: Int J Mol Sci

PubMed ID: 38928038

Doi: 10.3390/ijms25126331

Products & Services: Catalog Peptides

A quadrivalent recombinant influenza Hemagglutinin vaccine induced strong protective immune responses in animal models

Authors: Jin Feng, Yingying Du, Liyun Chen, Wenhan Su, Hailiu Wei, Aijiao Liu, Xiaojun Jiang, Jianmin Guo, Cailing Dai, Yuhua Xu, Tao Peng

Journal: Vaccine

PubMed ID: 38834431

Doi: 10.1016/j.vaccine.2024.05.056

Products & Services: Proteins, Expression, Isolation and Analysis Peptide Library Services

Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex

Authors: Qiyin An, Yong Wang, Zhenhua Tian, Jie Han, Jinyue Li, Fumeng Liao, Feiyang Yu, Haiyan Zhao, Yancheng Wen, Heng Zhang & Zengqin Deng

Journal: Cell Research

PubMed ID: 38834762

Doi: 10.1038/s41422-024-00981-w

Products & Services: Proteins, Expression, Isolation and Analysis

XIST dampens X chromosome activity in a SPEN-dependent manner during early human development

Authors: Charbel Alfeghaly, Gaël Castel, Emmanuel Cazottes, Madeleine Moscatelli, Eva Moinard, Miguel Casanova, Juliette Boni, Kasturi Mahadik, Jenna Lammers, Thomas Freour, Louis Chauviere, Carla Piqueras, Ruben Boers, Joachim Boers, Joost Gribnau, Laurent David, Jean-François Ouimette & Claire Rougeulle

Journal: Nat Struct Mol Biol

PubMed ID: 38834912

Doi: 10.1038/s41594-024-01325-3

Products & Services: Custom DNA/RNA Oligos

Characterization and regulation of cell cycle-independent noncanonical gene targeting

Authors: Shinta Saito & Noritaka Adachi

Journal: Nature Communications

PubMed ID: 38890315

Doi: 10.1038/s41467-024-49385-9.

Products & Services: Gene Synthesis

Intein-mediated temperature control for complete biosynthesis of sanguinarine and its halogenated derivatives in yeast

Authors: Yuanwei Gou, Dongfang Li, Minghui Zhao, Mengxin Li, Jiaojiao Zhang, Yilian Zhou, Feng Xiao, Gaofei Liu, Haote Ding, Chenfan Sun, Cuifang Ye, Chang Dong, Jucan Gao, Di Gao, Zehua Bao, Lei Huang, Zhinan Xu, Jiazhang Lian

Journal: Nat Commun

PubMed ID: 38898098

Doi: 10.1038/s41467-024-49554-w

Products & Services: Gene Synthesis

An emerging antibacterial nanovaccine for enhanced chemotherapy by selectively eliminating tumor-colonizing bacteria

Authors: Linfu Chen a, Zheyu Kang a, Jingjing Shen a, Rui Zhao a, Yu Miao a, Lin Zhang b, Zixuan Zheng c, Zhemin Zhang c, Nanhui Liu a, Cheng Wang a, Huapan Fang a, Jun Zhou a, Yudong Wang b, Zhuang Liu a, Yang Yang c, Qian Chen

Journal: Science Bulletin

Doi: doi.org/10.1016/j.scib.2024.06.016

Products & Services: Molecular Biology Reagents

Highly biased agonism for GPCR ligands via nanobody tethering

Authors: Shivani Sachdev, Brendan A Creemer, Thomas J Gardella, Ross W Cheloha

Journal: Nat Commun

PubMed ID: 38824166

Doi: 10.1038/s41467-024-49068-5.

Products & Services: Proteins, Expression, Isolation and Analysis PCR Cloning and Subcloning

BRET-based biosensors for SARS-CoV-2 oligonucleotide detection

Authors: Asfia Sultana, Anupriya M Geethakumari, Zeyaul Islam, Prasanna R Kolatkar, Kabir H Biswas

Journal: Front Bioeng Biotechnol