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Scalable modulation of CRISPR‒Cas enzyme activity using photocleavable phosphorothioate DNA
Authors: Menglu Hu, Bingni Zhang, Yuanyue Shan, Feng Cao, Yihui Wang, Weiwei Qi, Xue Wang, Yuting Shen, Xinyi Guo, Mengmeng Zhang, Tian Tian, Wei Xie, Mingfeng Zhang, Fang Liang, Duanqing Pei, Xiaoming Zhou
Journal: Nature Communications
PubMed ID: 40593724
Doi: 10.1038/s41467-025-61094-5
Products & Services: Synthetic Guide RNA   
Safety and immunogenicity of intranasal parainfluenza virus type 5 (PIV5)-vectored COVID-19 vaccine in adults and teens in an open-label phase 1 trial
Authors: Paul Spearman, Hong Jin, Peng Xiao, Kristeene Knopp, Henry Radziewicz, Marinka Tellier, Sasha E Larsen, Bryan J Berube, Xiao Song, Jamie Kidd, Karnail Singh, Zhuo Li, Maria Cristina Gingerich, Samuel Wu, Susan P John, Angela Branche, Ann R Falsey, Rhea Coler, Francois J Villinger, Biao He
Journal: SCIENCE ADVANCES
PubMed ID: 40614182
Doi: 10.1126/sciadv.adw0896
Products & Services: Peptide Library Services   
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI
Authors: Benjamin Bourgeois, Emil Spreitzer, Daniel Platero-Rochart, Margret Paar, Qishun Zhou, Sinem Usluer, Peter L J de Keizer, Boudewijn M T Burgering, Pedro A Sánchez-Murcia, Tobias Madl
Journal: Nature Communications
PubMed ID: 40593617
Doi: 10.1038/s41467-025-60844-9
Products & Services: Bacterial Expression   
Pericyte pannexin1 controls cerebral capillary diameter and supports memory function
Authors: Sandra Mai-Morente, Eugenia Isasi, Alberto Rafael, Gonzalo Budelli, Silvia Olivera-Bravo, Nathalia Vitureira, Verónica Abudara
Journal: Nature Communications
PubMed ID: 40610448
Doi: 10.1038/s41467-025-61312-0
Products & Services: Peptide Synthesis   
Oropouche virus infects human trophoblasts and placenta explants
Authors: Christina J Megli, Rebecca K Zack, Jackson J McGaughey, Ryan M Hoehl, Taylor Snisky, Amy L Hartman, Cynthia M McMillen
Journal: Nature Communications
PubMed ID: 40593852
Doi: 10.1038/s41467-025-61138-w
Products & Services: Monoclonal Antibody Services   
An adaptive peptide-binding site in ubiquitin receptor hRpn13 revealed by structural studies
Authors: Bakar Hassan, Monika Chandravanshi, Martin Y Ng, Hitendra Negi, Brice A P Wilson, Kylie J Walters
Journal: Nature Communications
PubMed ID: 40595513
Doi: 10.1038/s41467-025-60843-w
Products & Services: Peptide Synthesis   
Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
Authors: Kevin Sek, Amanda X Y Chen, Thomas Cole, Jesse D Armitage, Junming Tong, Kah Min Yap, Isabelle Munoz, Phoebe A Dunbar, Shiyi Wu, Marit J van Elsas, Olivia Hidajat, Christina Scheffler, Lauren Giuffrida, Melissa A Henderson, Deborah Meyran, Fernando Souza-Fonseca-Guimaraes, Dat Nguyen, Yu-Kuan Huang, Maria N de Menezes, Emily B Derrick, Cheok Weng Chan, Kirsten L Todd, Jack D Chan, Jasmine Li, Junyun Lai, Emma V Petley, Sherly Mardiana, Anthony Bosco, Jason Waithman, Ian A Parish, Christina Mølck, Gregory D Stewart, Lev Kats, Imran G House, Phillip K Darcy, Paul A Beavis
Journal: Nature Communications
PubMed ID: 40610421
Doi: 10.1038/s41467-025-59021-9
Regulating the N-oxidation selectivity of P450BM3 monooxygenases for N-heterocycles through computer-assisted structure-guided design
Authors: Liu Yang, Zhongji Pu, Jianping Wu, Xiaofeng Liu, Zhe Wang, Haoran Yu, Liuwei Wang, Yan Meng, Gang Xu, Lirong Yang, Wenlong Zheng
Journal: Nature Communications
PubMed ID: 40659637
Doi: 10.1038/s41467-025-61773-3
Products & Services: Protein Electrophoresis and Western   
Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity
Authors: Tao Jiang, Shuaiyang Jing, Haojun Li, Bao Xiao, Jiahui Jin, Xiu Sun, Juan Wang, Jing Liang, Tongze Cai, Huili Hu, Meilan Wei, Xuanrui Zhong, Yang Ji, Peng George Wang, Jianlong Zhou
Journal: Advanced Science
PubMed ID: 40652522
Doi: 10.1002/advs.202417205
Products & Services: PCR Cloning and Subcloning   
Divergent Delivery and Expression Kinetics of Lipid and Polymeric Nanoparticles across mRNA Modalities
Authors: Irafasha C Casmil, Josh J Friesen, Nuthan V Bathula, Anneke Strumpel, Chia Hao Ho, Ilana Guez, Kristen Y S Kong, Andrew J Varley, Shigeki J Miyake-Stoner, Parinaz Aliahmad, Nathaniel S Wang, Andrew J Geall, Anna K Blakney
Journal: Advanced Science
PubMed ID: 40650657
Doi: 10.1002/advs.202508907
Products & Services: Circular RNA synthesis   
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