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Discovery and pharmacophoric characterization of chemokine network inhibitors using phage-display, saturation mutagenesis and computational modelling

Authors: Serena Vales, Jhanna Kryukova, Soumyanetra Chandra, Gintare Smagurauskaite, Megan Payne, Charlie J Clark, Katrin Hafner, Philomena Mburu, Stepan Denisov, Graham Davies, Carlos Outeiral, Charlotte M Deane, Garrett M Morris, Shoumo Bhattacharya

Journal: Nat Commun

PubMed ID: 37717048

Doi: 10.1038/s41467-023-41488-z

Products & Services: Peptide Synthesis

Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors

Authors: Matteo Righi, Isaac Gannon, Matthew Robson, Saket Srivastava, Evangelia Kokalaki, Thomas Grothier, Francesco Nannini, Christopher Allen, Yuchen V Bai, James Sillibourne, Shaun Cordoba, Simon Thomas, Martin Pule

Journal: Cancer Immunol Res

PubMed ID: 37352396

Doi: 10.1158/2326-6066.CIR-22-0640

Products & Services: Protein and Antibody Isolation

Discovery and identification of a novel canine coronavirus causing a diarrhea outbreak in Vulpes

Authors: Yuting Liu, Yao Deng, Sheng Niu, Na Zhu, Jingdong Song, Xiaoshuang Zhang, Weiting Su, Wenhui Nie, Roujian Lu, David M Irwin, George Fu Gao, Wenling Wang, Qihui Wang, Wenjie Tan, Shuyi Zhang

Journal: Sci Bull (Beijing)

PubMed ID: 37758615

Doi: 10.1016/j.scib.2023.09.011

Products & Services: Molecular Biology Reagents

The Dictyostelium discoideum FimA protein, unlike yeast and plant fimbrins, is regulated by calcium similar to mammalian plastins

Authors: Hiroaki Ishida, Andrew G Woodman, Naoya Kitada, Tomoyasu Aizawa, Hans J Vogel

Journal: Sci Rep

PubMed ID: 37758724

Doi: 10.1038/s41598-023-42682-1

Products & Services: Molecular Biology Reagents

Functional and structural analyses reveal that a dual domain sialidase protects bacteria from complement killing through desialylation of complement factors

Authors: Nicholas D Clark, Christopher Pham, Kurni Kurniyati, Ching Wooen Sze, Laurynn Coleman, Qin Fu, Sheng Zhang, Michael G Malkowski, Chunhao Li

Journal: PLoS Pathog

PubMed ID: 37747935

Doi: 10.1371/journal.ppat.1011674

Products & Services: Molecular Biology Reagents

An mRNA-based broad-spectrum vaccine candidate confers cross-protection against heterosubtypic influenza A viruses

Authors: Feifei Xiong, Chi Zhang, Baoyuan Shang, Mei Zheng, Qi Wang, Yahong Ding, Jian Luo, Xiuling Li

Journal: Emerg Microbes Infect

PubMed ID: 37671994

Doi: 10.1080/22221751.2023.2256422

Products & Services: Peptide Synthesis

A digital twin for DNA data storage based on comprehensive quantification of errors and biases

Authors: Andreas L Gimpel, Wendelin J Stark, Reinhard Heckel, Robert N Grass

Journal: Nat Commun

PubMed ID: 37758710

Doi: 10.1038/s41467-023-41729-1

Products & Services: PCR Cloning and Subcloning

Adipose‑derived stem cell‑mediated alphastatin targeting delivery system inhibits angiogenesis and tumor growth in glioma

Authors: Chen Liang, Ting Wei, Ting Zhang, Chen Niu

Journal: Mol Med Rep

PubMed ID: 37772382

Doi: 10.3892/mmr.2023.13102

Products & Services: Peptide Synthesis

Cryo-EM structures of human organic anion transporting polypeptide OATP1B1

Authors: Ziyang Shan, Xuemei Yang, Huihui Liu, Yafei Yuan, Yuan Xiao, Jing Nan, Wei Zhang, Wenqi Song, Jufang Wang, Feiwen Wei, Yanqing Zhang

Journal: Cell Res

PubMed ID: 37674011

Doi: 10.1038/s41422-023-00870-8

Products & Services: Protein and Antibody Isolation

Enterococcus faecium C171: Modulating the Immune Response to Acute Lethal Viral Challenge

Authors: Jielan Mi, Tana He, Xinyun Hu, Zhihao Wang, Tingting Wang, Xiaole Qi, Kai Li, Li Gao, Changjun Liu, Yanping Zhang, Suyan Wang, Yu Qiu, Zengqi Liu, Jie Song, Xiaomei Wang, Yulong Gao, Hongyu Cui

Journal: Int J Antimicrob Agents

PubMed ID: 37758064

Doi: 10.1016/j.ijantimicag.2023.106969

Products & Services: Protein and Antibody Isolation