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Highly efficient hybridoma generation and screening strategy for anti-PD-1 monoclonal antibody development

Authors: Tanapati Phakham, Chatikorn Boonkrai, Tossapon Wongtangprasert, Thittaya Audomsun, Chadaporn Attakitbancha, Pijitra Saelao, Phijitra Muanwien, Sarintip Sooksai, Nattiya Hirankarn, Trairak Pisitkun

Journal: Sci Rep

PubMed ID: 36273231

Doi: 10.1038/s41598-022-20560-6

Products & Services: Stable Cell Lines

Hydrogen-bonds mediate liquid-liquid phase separation of mussel derived adhesive peptides

Authors: Qi Guo, Guijin Zou, Xuliang Qian, Shujun Chen, Huajian Gao, Jing Yu

Journal: Nat Commun

PubMed ID: 36182948

Doi: 10.1038/s41467-022-33545-w

Products & Services: Catalog Peptides

An experimental test of the nicotinic hypothesis of COVID-19

Authors: Nicole E Godellas, Gisela D Cymes, Claudio Grosman

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36279466

Doi: 10.1073/pnas.2204242119

Products & Services: Catalog Peptides

Ultra-sensitive molecular detection of gene fusions from RNA using ASPYRE

Authors: Eleanor R Gray, Justyna M Mordaka, Efthimia R Christoforou, Kristine von Bargen, Nicola D Potts, Christina Xyrafaki, Ana-Luisa Silva, Magdalena Stolarek-Januszkiewicz, Katarzyna Anton, Paulina K Powalowska, Simonetta Andreazza, Alessandro Tomassini, Rebecca N Palmer, Aishling Cooke, Robert J Osborne, Barnaby W Balmforth

Journal: BMC Med Genomics

PubMed ID: 36224552

Doi: 10.1186/s12920-022-01363-0

Products & Services: Custom DNA/RNA Oligos

PCDetection: PolyA-CRISPR/Cas12a-based miRNA detection without PAM restriction

Authors: Mingtian Zhong , Kaizhao Chen , Wenjun Sun , Xiangyang Li , Shisheng Huang , Qingzhou Meng , Bo Sun , Xingxu Huang , Xinjie Wang , Xiaodong Ma , Peixiang Ma

Journal: Biosens Bioelectron

PubMed ID: 35797934

Doi: 10.1016/j.bios.2022.114497

Products & Services: Gene Synthesis

A switchable Cas12a enabling CRISPR-based direct histone deacetylase activity detection

Authors: Wenyuan Kang , Lin Liu , Peihang Yu , Tianyi Zhang , Chunyang Lei , Zhou Nie

Journal: Biosens Bioelectron

PubMed ID: 35700604

Doi: doi.org/10.1016/j.bios.2022.114468

Products & Services: Gene Synthesis

Asymmetric Stratification-Induced Polarity Loss and Coordinated Individual Cell Movements Drive Directional Migration of Vertebrate Epithelium

Authors: Yunzhe Lu , Ruolan Deng , Huanyang You , Yishu Xu , Christopher Antos , Jianlong Sun , Ophir D Klein , Pengfei Lu

Journal: Cell Rep

PubMed ID: 33053348

Doi: 10.1016/j.celrep.2020.108246

Products & Services: Recombinant Proteins

Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone

Authors: Yongrui Liu , Yue Li , Hongyu Bao , Yanhong Liu , Liu Chen , Hongda Huang

Journal: J Mol Biol

PubMed ID: 35870648

Doi: 10.1016/j.jmb.2022.167756

Products & Services: Gene Synthesis

De novo design of anti-tuberculosis agents using a structure-based deep learning method

Authors: Sowmya Ramaswamy Krishnan, Navneet Bung, Siladitya Padhi, Gopalakrishnan Bulusu, Parimal Misra, Manojit Pal, Srinivas Oruganti, Rajgopal Srinivasan, Arijit Roy

Journal: J Mol Graph Model

PubMed ID: 36257148

Doi: 10.1016/j.jmgm.2022.108361

Products & Services: Plasmid DNA Preparation

Long noncoding RNA-mediated activation of PROTOR1/PRR5-AKT signaling shunt downstream of PI3K in triple-negative breast cancer

Authors: Zhenbo Tu, Yi Hu, Devesh Raizada, Mahmoud A Bassal, Daniel G Tenen, Antoine E Karnoub

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36269860

Doi: 10.1073/pnas.2203180119

Products & Services: Mammalian Expression