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Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

Authors: Damon A Hofman, Jorge Ruiz-Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Karl R Clauser, Alexandra L Condurat, Jip T van Dinter, Sem A G Engels, Amy Goodale, Jasper van der Lugt, Tanaz Abid, Li Wang, Kevin N Zhou, Jayne Vogelzang, Keith L Ligon, Timothy N Phoenix, Jennifer A Roth, David E Root, Norbert Hubner, Todd R Golub, Pratiti Bandopadhayay, Sebastiaan van Heesch, John R Prensner

Journal: biorxiv

PubMed ID: 37205492

Doi: 10.1101/2023.05.04.539399

Products & Services: Protein and Antibody Isolation

Ovarian juvenile granulosa cell tumors with Ollier's disease in children with IDH1 gene somatic mutation

Authors: Jin Zhang, Renwu Hua, Lishuang Ma, Chao Liu, Yanxia Zhang, Xuemin Lü, Tianren Wang, Naijun Wan

Journal: Front Endocrinol (Lausanne)

PubMed ID: 37324278

Doi: 10.3389/fendo.2023.1093273

Products & Services: Protein and Antibody Isolation

MASP3 Deficiency in Mice Reduces but Does Not Abrogate Alternative Pathway Complement Activity Due to Intrinsic Profactor D Activity

Authors: Damodar Gullipalli, Takashi Miwa, Madhu Golla, Sayaka Sato, Sree Angampalli, Wen-Chao Song

Journal: J Immunol

PubMed ID: 36988282

Doi: 10.4049/jimmunol.2200932

Products & Services: Gene Synthesis

Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex

Authors: Mandy S M Wan, Reyhan Muhammad, Marios G Koliopoulos, Theodoros I Roumeliotis, Jyoti S Choudhary, Claudio Alfieri

Journal: Nature Communications

PubMed ID: 37137925

Doi: 10.1038/s41467-023-38276-0

Products & Services: Gene Synthesis

KREH1 RNA helicase activity promotes utilization of initiator gRNAs across multiple mRNAs in trypanosome RNA editing

Authors: Ashutosh P Dubey, Brianna L Tylec, Amartya Mishra, Katherine Sortino, Runpu Chen, Yijun Sun, Laurie K Read

Journal: Nucleic Acids Research

PubMed ID: 37140035

Doi: doi.org/10.1093/nar/gkad292

Products & Services: Gene Synthesis

BcMYB111 Responds to BcCBF2 and Induces Flavonol Biosynthesis to Enhance Tolerance under Cold Stress in Non-Heading Chinese Cabbage

Authors: Xiaoshan Chen , Ying Wu , Zhanghong Yu , Zhanyuan Gao , Qiang Ding , Sayyed Hamad Ahmad Shah , Wenyuan Lin , Ying Li , Xilin Hou

Journal: Int J Mol Sci .

PubMed ID: 37240015

Doi: 10.3390/ijms24108670

Products & Services: Gene Synthesis

Engineered ketocarotenoid biosynthesis in the polyextremophilic red microalga Cyanidioschyzon merolae 10D

Authors: Mark Seger , Fakhriyya Mammadova , Melany Villegas-Valencia , Barbara ´ Bastos de Freitas , Clarissa Chang , Iona Isachsen , Haley Hemstreet , Fatimah Abualsaud , Malia Boring , Peter J. Lammers , Kyle J. Lauersen

Journal: Metabolic engineering communications

Doi: 10.1016/j.mec.2023.e00226

Products & Services: Gene Synthesis

Safety and Efficacy of Intravenous and Intrathecal Delivery of AAV9-Mediated ARSA in Minipigs

Authors: Aysilu Mullagulova , Alisa Shaimardanova , Valeriya Solovyeva , Yana Mukhamedshina , Daria Chulpanova , Alexander Kostennikov, Shaza Issa, Albert Rizvanov

Journal: Int J Mol Sci .

PubMed ID: 37298156

Doi: 10.3390/ijms24119204

Products & Services: Gene Synthesis

FOSL2 promotes intertumoral infiltration of T cells and increases pathological complete response rates in locally advanced rectal cancer patients

Authors: Kailun Xu, Xiaoyang Yin, Biting Zhou, Xi Zheng, Hao Wang, Jing Chen, Xue Cai, Huanhuan Gao, Xiaoming Xu, Liuhong Wang, Li Shen, Tiannan Guo, Shu Zheng, Baosheng Li, Yingkuan Shao, Jian Wang

Journal: Cancer Letters

PubMed ID: 36997107

Doi: 10.1016/j.canlet.2023.216145

Products & Services: Synthetic Guide RNA

Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex

Authors: Cassandra K Hayne, Kevin John U Butay, Zachary D Stewart, Juno M Krahn, Lalith Perera, Jason G Williams, Robert M Petrovitch, Leesa J Deterding, A Gregory Matera, Mario J Borgnia, Robin E Stanley

Journal: Nat Struct Mol Biol

PubMed ID: 37231153

Doi: 10.1038/s41594-023-00991-z

Products & Services: Gene Synthesis