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Antibody aggregation can lead to reduced Protein A binding capacity and low step yield

Authors: Gaoya Yuan, Meng Qu, Qi Geng, Wanyuan Dong, Xudong Zhang, Yifeng Li

Journal: Protein Expr Purif

PubMed ID: 37271409

Doi: 10.1016/j.pep.2023.106315

Products & Services: Protein Electrophoresis and Western

Folding Double-Stranded DNA into Designed Shapes with Triplex-Forming Oligonucleotides

Authors: Cindy Ng , Anirban Samanta , Ole Aalund Mandrup , Emily Tsang , Sarah Youssef , Lasse Hyldgaard Klausen , Mingdong Dong , Minke A D Nijenhuis , Kurt V Gothelf

Journal: Adv Mater .

PubMed ID: 37311656

Doi: 10.1002/adma.202302497

Products & Services: DNA Sequencing

A mitotic NADPH upsurge promotes chromosome segregation and tumour progression in aneuploid cancer cells

Authors: Aoxing Cheng, Tian Xu , Weiyi You, Ting Wang, Dongming Zhang, Huimin Guo , Haiyan Zhang , Xin Pan , Yucai Wang , Liu Liu , Kaiguang Zhang , Jue Shi , Xuebiao Yao ， Jing Guo , Zhenye Yang

Journal: Nat Metab .

PubMed ID: 37349486

Doi: 10.1038/s42255-023-00832-9

Products & Services: Antibody Modification and Purification Services

Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models

Authors: Sujin Zhou, Yan Lin, Zhenggang Zhao, Yunhao Lai, Mengmeng Lu, Zishen Shao, Xinyu Mo, Yunping Mu, Zhipeng Liang, Xinxing Wang, Jingming Qu, Hua Shen, Fanghong Li, Allan Z Zhao

Journal: Cell Rep Med

PubMed ID: 37269826

Doi: 10.1016/j.xcrm.2023.101070

Products & Services: Custom Vector Construction

ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway

Authors: Songnan Wang, Volker Böhnert, Alby J Joseph, Valentino Sudaryo, Jason Swinderman, Feiqiao B Yu, Xuchao Lyu, Gemini Skariah, Vishvak Subramanyam, Luke A Gilbert, Hani Goodarzi, Li Lingyin

Journal: biorxiv

PubMed ID: 37333273

Doi: 10.1101/2023.06.01.543353

Products & Services: Protein and Antibody Isolation

CLDN182 and 4-1BB bispecific antibody givastomig exerts antitumor activity through CLDN182-expressing tumor-directed T-cell activation

Authors: Jing Gao, Zhengyi Wang, Wenqing Jiang, Yanni Zhang, Zhen Meng, Yanling Niu, Zhen Sheng, Chan Chen, Xuejun Liu, Xi Chen, Chanjuan Liu, Keren Jia, Cheng Zhang, Haiyan Liao, Jaeho Jung, Eunsil Sung, Hyejin Chung, Jingwu Z Zhang, Andrew X Zhu, Lin Shen

Journal: J Immunother Cancer

PubMed ID: 37364935

Doi: 10.1136/jitc-2023-006704

Products & Services: Protein and Antibody Isolation

Development and qualification of cell-based relative potency assay for a human respiratory syncytial virus (RSV) mRNA vaccine

Authors: Hualin Helen Li, Jenny Xu, Li He, Lynne Ireland Denny, Richard R Rustandi, Geethanjali Dornadula, Brock Fiorito, Zhi-Qiang Zhang

Journal: J Pharm Biomed Anal

PubMed ID: 37336039

Doi: 10.1016/j.jpba.2023.115523

Products & Services: Protein and Antibody Isolation

Compound from Magnolia officinalis Ameliorates White Matter Injury by Promoting Oligodendrocyte Maturation in Chronic Cerebral Ischemia Models

Authors: Zhi Zhang, Xin Shu, Qian Cao, Lushan Xu, Zibu Wang, Chenggang Li, Shengnan Xia, Pengfei Shao, Xinyu Bao, Liang Sun, Yuhao Xu, Yun Xu

Journal: Neurosci Bull

PubMed ID: 37291477

Doi: 10.1007/s12264-023-01068-z

Products & Services: Protein and Antibody Isolation

Protein-protein interactions between tenascin-R and RPTPζ/phosphacan are critical to maintain the architecture of perineuronal nets

Authors: Ashis Sinha, Jessica Kawakami, Kimberly S Cole, Aliona Ladutska, Mary Y Nguyen, Mary S Zalmai, Brandon L Holder, Victor M Broerman, Russell T Matthews, Samuel Bouyain

Journal: J Biol Chem

PubMed ID: 37356715

Doi: 10.1016/j.jbc.2023.104952

Products & Services: Protein and Antibody Isolation

Durable contraception in the female domestic cat using viral-vectored delivery of a feline anti-Müllerian hormone transgene

Authors: Lindsey M Vansandt, Marie-Charlotte Meinsohn, Philippe Godin, Nicholas Nagykery, Natalie Sicher, Motohiro Kano, Aki Kashiwagi, Maeva Chauvin, Hatice D Saatcioglu, Julie L Barnes, Amy G Miller, Amy K Thompson, Helen L Bateman, Elizabeth M Donelan, Raquel González, Jackie Newsom, Guangping Gao, Patricia K Donahoe, Dan Wang, William F Swanson, David Pépin

Journal: Nat Commun

PubMed ID: 37280258

Doi: 10.1038/s41467-023-38721-0

Products & Services: Codon Optimization