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Identification of paeoniflorin from Paeonia lactiflora pall As an inhibitor of tryptophan 2,3-dioxygenase and assessment of its pharmacological effects on depressive mice

Authors: Xiaoxia Liang, Ting Su, Pingzhou Wu, Yanting Dai, Yanmin Chen, QiQi Wang, Cheng Cao, Fenglian Chen, Qing Wang, Shuling Wang

Journal: J Ethnopharmacol

PubMed ID: 37315645

Doi: 10.1016/j.jep.2023.116714

Products & Services: Protein and Antibody Isolation

Antibody aggregation can lead to reduced Protein A binding capacity and low step yield

Authors: Gaoya Yuan, Meng Qu, Qi Geng, Wanyuan Dong, Xudong Zhang, Yifeng Li

Journal: Protein Expr Purif

PubMed ID: 37271409

Doi: 10.1016/j.pep.2023.106315

Products & Services: Protein Electrophoresis and Western

Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos

Authors: Liang Chen, Mengjia Hong, Changming Luan, Hongyi Gao, Gaomeng Ru, Xinyuan Guo, Dujuan Zhang, Shun Zhang, Changwei Li, Jun Wu, Peyton B Randolph, Alexander A Sousa, Chao Qu, Yifan Zhu, Yuting Guan, Liren Wang, Mingyao Liu, Bo Feng, Gaojie Song, David R Liu, Dali Li

Journal: Nat Biotechnol

PubMed ID: 37322276

Doi: 10.1038/s41587-023-01821-9

Products & Services: Custom mRNA synthesis Synthetic Guide RNA

Effect of moderate prenatal ethanol exposure on the differential expression of two histamine H3 receptor isoforms in different brain regions of adult rat offspring

Authors: Suzy Davies, Kiana S Lujan, Ella J Rappaport, Carlos F Valenzuela, Daniel D Savage

Journal: Front Neurosci

PubMed ID: 37449267

Doi: 10.3389/fnins.2023.1192096

Products & Services: Protein and Antibody Isolation

Multisite transformation in : insights on transformations mechanisms and new genetic modification protocols

Authors: Vui Yin Seow, Olga Tsygelnytska, Nicolas Biais

Journal: Front Microbiol

PubMed ID: 37408636

Doi: 10.3389/fmicb.2023.1178128

Products & Services: Gene Synthesis

A novel self-purified auxiliary protein enhances the lichenase activity towards lichenan for biomass degradation

Authors: Rui Zhou, Lingzhi Zhang, Bo Zeng, Yanhong Zhou, Wenhui Jin, Guangya Zhang

Journal: Appl Microbiol Biotechnol

PubMed ID: 37272940

Doi: 10.1007/s00253-023-12608-y

Products & Services: Protein and Antibody Isolation

Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases

Authors: Victoria A Kleiner, Thierry O Fischmann, John A Howe, Douglas C Beshore, Michael J Eddins, Yan Hou, Todd Mayhood, Daniel Klein, Debbie D Nahas, Bob J Lucas, He Xi, Edward Murray, Daphne Y Ma, Krista Getty, Rachel Fearns

Journal: Commun Biol

PubMed ID: 37337079

Doi: 10.1038/s42003-023-04990-0

Products & Services: Codon Optimization

MERS-CoV RBD-mRNA vaccine induces potent and broadly neutralizing antibodies with protection against MERS-CoV infection

Authors: Wanbo Tai, Jian Zheng, Xiujuan Zhang, Juan Shi, Gang Wang, Xiaoqing Guan, Jiang Zhu, Stanley Perlman, Lanying Du

Journal: Virus Res

PubMed ID: 37336390

Doi: 10.1016/j.virusres.2023.199156

Products & Services: Molecular Biology Reagents

Two Recombinant Bacteriocins, Rhamnosin and Lysostaphin, Show Synergistic Anticancer Activity Against Gemcitabine-Resistant Cholangiocarcinoma Cell Lines

Authors: Kankamol Kerdkumthong, Wannarat Chanket, Phanthipha Runsaeng, Sutthipong Nanarong, Kawinnath Songsurin, Phonprapavee Tantimetta, Chanan Angsuthanasombat, Aratee Aroonkesorn, Sumalee Obchoei

Journal: Probiotics Antimicrob Proteins

PubMed ID: 37294416

Doi: 10.1007/s12602-023-10096-0

Products & Services: Molecular Biology Reagents

Rapid and Facile Light-Based Approach to Fabricate Protease-Degradable Poly(ethylene glycol)-norbornene Microgels for Cell Encapsulation

Authors: Ana Mora-Boza, Saron G Ghebrezadik, Johannes E Leisen, Andrés J García

Journal: Adv Healthc Mater

PubMed ID: 37235850

Doi: 10.1002/adhm.202300942

Products & Services: Molecular Biology Reagents