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Internal ribosome entry sites enhance translation in trans in antisense non-coding SINEUP and circular RNAs

Authors: Sabrina D'Agostino, Abraham Tettey-Matey, Massimiliano Volpe, Bianca Pierattini, Mattia D'Agostino, Denisa Smělá, Federico Ansaloni, Laura Broglia, Pierre Lau, Omar Peruzzo, Clarissa Braccia, Andrea Armirotti, Margherita Scarpato, Devid Damiani, Gloria Ros, Valerio Di Carlo, Federica Maniscalco, Elias Bechara, Gian Gaetano Tartaglia, Piero Carninci, Claudio Santoro, Francesca Persichetti, Luca Pandolfini, Angelita Simonetti, Stefano Espinoza, Silvia Zucchelli, Remo Sanges, Carlotta Bon, Stefano Gustincich

Journal: Nucleic Acids Research

PubMed ID: 40823812

Doi: 10.1093/nar/gkaf788

Products & Services: Custom Vector Construction

The NSP5, ORF6 and NSP13 of SARS-CoV-2 Cooperate to Modulate Inflammatory Cell Death Activation

Authors: Huan Wang, Mengdi Liang, Jing Zhang, Hua Tong, Fenfen Zhang, Ying Liu, Pui Wang, Mengmeng Chang, Fei Han, Siwen Liu, Yongping Lin, Wenjun Song, Rajendra Karki, Peihui Wang, Honglin Chen, Yang Liu, Min Zheng

Journal: Advanced Science

PubMed ID: 40810650

Doi: 10.1002/advs.202503977

Products & Services: Protein and Antibody Isolation

Functional and epitope specific monoclonal antibody discovery directly from immune sera using cryo-EM

Authors: James A Ferguson, Sai Sundar Rajan Raghavan, Garazi Peña Alzua, Disha Bhavsar, Jiachen Huang, Alesandra J Rodriguez, Jonathan L Torres, Maria Bottermann, Julianna Han, Florian Krammer, Facundo D Batista, Andrew B Ward

Journal: SCIENCE ADVANCES

PubMed ID: 40815640

Doi: 10.1126/sciadv.adv8257

Products & Services: Recombinant Antibody Expression

Structural basis for small molecule binding to the SARS-CoV-2 nsp10-nsp14 ExoN complex

Authors: Frank Kozielski, Suzanne Zoë Fisher, Shumeng Ma, Fatma Al Busaidi, Ewa Krupinska, Maria Nyblom, Céleste Sele, Heather McDuffie Sullivan, Tobias Krojer, Wolfgang Knecht

Journal: Nucleic Acids Research

PubMed ID: 40794865

Doi: 10.1093/nar/gkaf753

Products & Services: Codon Optimization

Expanding the cytokine receptor alphabet reprograms T cells into diverse states

Authors: Yang Zhao, Masato Ogishi, Aastha Pal, Leon L. Su, Pingdong Tao, Hua Jiang, Grayson E. Rodriguez, Xiaojing Chen, Qinli Sun, Lea Wenting Rysavy, Sam Limsuwannarot, Deepa Waghray, Anusha Kalbasi, K. Christopher Garcia

Journal: Nature

PubMed ID: 40804519

Doi: 10.1038/s41586-025-09393-1.

Products & Services: Peptide Synthesis

Structural insights into Type II-D Cas9 and its robust cleavage activity

Authors: Kangkang Wang, Jiuyu Wang, Xiaoqi Yang, Wei Sun, Gang Sheng, Yanli Wang

Journal: Nature Communications

PubMed ID: 40790018

Doi: 10.1038/s41467-025-62128-8.

Products & Services: Codon Optimization

Anti-CV2/CRMP5 autoantibodies as drivers of sensory neuron excitability and pain in rats

Authors: Laurent Martin, Harrison J Stratton, Lyuba Y Salih, Nicolas LA Dumaire, Kimberly Gomez, Le Duy Do, Santiago Loya-Lopez, Cheng Tang, Aida Calderon-Rivera, Dongzhi Ran, Venkatrao Nunna, Shreya S Bellampalli, Liberty François-Moutal, Shizhen Luo, Frank Porreca, Mohab Ibrahim, Véronique Rogemond, Jérôme Honnorat, Rajesh Khanna, Aubin Moutal

Journal: Nature Communications

PubMed ID: 40775229

Doi: 10.1038/s41467-025-62380-y.

Products & Services: Peptide Synthesis

RNA Pol II inhibition activates cell death independently from the loss of transcription

Authors: Nicholas W Harper, Gavin A Birdsall, Megan E Honeywell, Kelly M Ward, Athma A Pai, Michael J Lee

Journal: Cell

PubMed ID: 40818455

Doi: 10.1016/j.cell.2025.07.034

Products & Services: Peptide Synthesis

FlaB-expressing bacterial uter membrane vesicles vaccine mediating anti-tumor immune response via promoting DCs activation and lymph nodes-homing

Authors: Kaiwei Wang, Chang Xu, Minming Chen, Yifan Yan, Nanhui Liu, Changhao Zhao, Bo Liu, Yanbin Liu, Jianjiang Chen, Xiaoliang Ding, Yicong Bian, Lin Song, Xuyu Bian, Yumin Wu, Liyan Miao, Zhuang Liu

Journal: Nano Research

PubMed ID: 40817136

Doi: 10.26599/NR.2025.94907612

Products & Services: ELISA Kits

In situ proximity labeling of proteins associated with circRNA and RNA G-quadruplexes

Authors: Jing Mo, Zonggui Chen, Manman Cui, Xin Fang, Ruihan Li, Shanshan Qin, Zhenlin Zhou, Mei Sun, Jinjun Wu, Chuan He, Fang Wang, Haojian Zhang, Xiang Zhou, Xiaocheng Weng

Journal: Nature Chemical Biology

PubMed ID: 40775047

Doi: 10.1038/s41589-025-01993-2

Products & Services: Protein Electrophoresis and Western