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Kinetic and Structural Characterization of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors

Authors: Kayla Glockzin, Kathleen M Meneely, Ryan Hughes, Sean W Maatouk, Grace E Piña, Kajitha Suthagar, Keith Clinch, Joshua N Buckler, Audrey L Lamb, Peter C Tyler, Thomas D Meek, Ardala Katzfuss

Journal: Biochemistry

PubMed ID: 37418678

Doi: 10.1021/acs.biochem.3c00116

Products & Services: Protein and Antibody Isolation

Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor

Authors: Wan Ni Chia, Chee Wah Tan, Aaron Wai Kit Tan, Barnaby Young, Tyler N Starr, Ester Lopez, Guntur Fibriansah, Jennifer Barr, Samuel Cheng, Aileen Ying-Yan Yeoh, Wee Chee Yap, Beng Lee Lim, Thiam-Seng Ng, Wan Rong Sia, Feng Zhu, Shiwei Chen, Jinyan Zhang, Madeline Sheng Si Kwek, Allison J Greaney, Mark Chen, Gough G Au, Prasad N Paradkar, Malik Peiris, Amy W Chung, Jesse D Bloom, David Lye, Sheemei Lok, Lin-Fa Wang

Journal: Sci Adv

PubMed ID: 37494438

Doi: 10.1126/sciadv.ade3470

Products & Services: Protein and Antibody Isolation

Role and neural regulation of clock genes in the rat pineal gland: Clock modulates amplitude of rhythmic expression of Aanat encoding the melatonin-producing enzyme

Authors: Aurea S Blancas-Velazquez, Tenna Bering, Signe Bille, Martin F Rath

Journal: J Pineal Res

PubMed ID: 37349875

Doi: 10.1111/jpi.12893

Products & Services: Protein and Antibody Isolation

Nanoengineered mesenchymal stem cell therapy for pulmonary fibrosis in young and aged mice

Authors: Meng-Meng Han , Xing-Yue He , Ling Tang , Liang Qi , Ming-Yuan Yang , Yi Wang , Lei Xing , Jee-Heon Jeong , Hu-Lin Jiang

Journal: Sci Adv .

PubMed ID: 37467328

Doi: 10.1126/sciadv.adg5358

Products & Services: Recombinant Proteins

Biomimetic Mineralized CRISPR/Cas RNA Nanoparticles forEfficient Tumor-Specific Multiplex Gene Editing

Authors: Yan Liang , Jingge Zhang , Chenlu Xu , Jinjin Wang , Wenshuai Han , Jiali Yang , Sixuan Wu , Jingyi An , Junjie Liu , Zhenzhong Zhang , Jinjin Shi , Kaixiang Zhang

Journal: ACS Nano .

PubMed ID: 37481734

Doi: 10.1021/acsnano.3c04116

Products & Services: Synthetic Guide RNA

Histone deacetylase III interactions with BK polyomavirus large tumor antigen may affect protein stability

Authors: Yueh-Han Hsu, Chun-Nun Chao, Hsin-Yi Huang, Pei-Wen Zhao, Pang-Hung Hsu, Cheng-Huang Shen, San-Yuan Chen, Chiung-Yao Fang

Journal: Virol J

PubMed ID: 37464367

Doi: 10.1186/s12985-023-02128-6

Products & Services: Molecular Biology Reagents

Development of quantitative multiplex RT-qPCR one step assay for detection of hepatitis delta virus

Authors: Jackson Alves da Silva Queiroz, Tárcio Peixoto Roca, Rutilene Barbosa Souza, Luiz Fellype Alves de Souza, Ana Maísa Passos-Silva, André Luiz Ferreira da Silva, Eugênia de Castro E Silva, Lourdes Maria Pinheiro Borzacov, Rita de Cássia Pontello Rampazzo, Soraya Dos Santos Pereira, Thor Oliveira Dantas, Janaína Mazaro, Lívia Melo Villar, Juan Miguel Villalobos Salcedo, Daniel Archimedes da Matta, Deusilene Vieira

Journal: Sci Rep

PubMed ID: 37495613

Doi: 10.1038/s41598-023-37756-z

Products & Services: Molecular Biology Reagents

Breakthrough SARS-CoV-2 Omicron Variant in Individuals Primed with Heterologous Vaccines Enhances Inhibition Performance of Neutralizing Antibody to BA2 Parental Lineage

Authors: Jidapa Szekely, Piyawut Swangphon, Natthaphon Nanakorn, Panuttha Chaimuti, Teerapat Nualnoi, Paweena Wongwitwichot, Namchoke Somapa, Denpong Somapa, Theerakamol Pengsakul

Journal: Vaccines (Basel)

PubMed ID: 37515045

Doi: 10.3390/vaccines11071230

Products & Services: Molecular Biology Reagents

Tepsin binds LC3B to promote ATG9A export and delivery at the cell periphery

Authors: Natalie S Wallace, John E Gadbery, Cameron I Cohen, Amy K Kendall, Lauren P Jackson

Journal: biorxiv

PubMed ID: 37502979

Doi: 10.1101/2023.07.18.549521

Products & Services: Protein and Antibody Isolation

Spatially-Encoding Hydrogels With DNA to Control Cell Signaling

Authors: Namrata Ramani, C Adrian Figg, Alex J Anderson, Peter H Winegar, EunBi Oh, Sasha B Ebrahimi, Devleena Samanta, Chad A Mirkin

Journal: Adv Mater

PubMed ID: 37221642

Doi: 10.1002/adma.202301086

Products & Services: Recombinant Proteins