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A new compact adenine base editor generated through deletion of HNH and REC2 domain of SpCas9

Authors: Yuqiang Qian , Di Wang , Wenchao Niu , Ding Zhao , Jinze Li , Zhiquan Liu , Xun Gao , Yang Han , Liangxue Lai , Zhanjun Li

Journal: BMC Biol .

PubMed ID: 37434184

Doi: 10.1186/s12915-023-01644-9

Products & Services: Synthetic Guide RNA

Chemo-enzymatic cascades producing 2,5- furandicarboxylic acid precursors via D-gluconate “barbell oxidation” and dehydration

Authors: Jiao Chen, a,b Jiali Cai,c Feng Sha,d Wenjun Sun,a Xilei Lyu,e Yonghui Chang,f Fei Cao, Lili Zhao, Hongli Wu and Pingkai Ouyang

Journal: Green Chem.

Doi: 10.1039/d3gc01493b

Products & Services: Gene Synthesis

Development of chimeric protein as a multivalent vaccine for human Kinetoplastid infections: Chagas disease and leishmaniasis

Authors: Marianna de Carvalho Clímaco, Luiza Almeida de Figueiredo, Rayane Cristina Lucas, Guilherme Rafael Gomide Pinheiro, Luísa Mourão Dias Magalhães, Ana Laura Grossi de Oliveira, Raquel Martins Almeida, Fernando Sérgio Barbosa, Daniella Castanheira Bartholomeu, Lilian Lacerda Bueno, Tiago Antonio Mendes, Bin Zhan, Kathryn Marie Jones, Peter Hotez, Maria Elena Bottazzi, Fabrício Marcus Silva Oliveira, Ricardo Toshio Fujiwara

Journal: Vaccine

PubMed ID: 37479612

Doi: 10.1016/j.vaccine.2023.07.020

Products & Services: Gene Synthesis

Integrated analysis and validation of TRIM23/p53 signaling pathway in hepatic stellate cells ferroptosis and liver fibrosis

Authors: Jie Chen, Rui Zhang, Feng Li, Shengli Lin, Jian Wang

Journal: Dig Liver Dis

PubMed ID: 37495427

Doi: 10.1016/j.dld.2023.07.010

Products & Services: Molecular Biology Reagents

TP5: A Novel Therapeutic Approach Targeting Aberrant and Hyperactive CDK5/p25 for the Treatment of Colorectal Carcinoma

Authors: Niranjana Amin, Herui Wang, Qi Song, Manju Bhaskar, Sharda Prasad Yadav, Mark R Gilbert, Harish Pant, Emeline Tabouret, Zhengping Zhuang

Journal: Int J Mol Sci

PubMed ID: 37511490

Doi: 10.3390/ijms241411733

Products & Services: Peptide Synthesis

Structural basis of CXC chemokine receptor 1 ligand binding and activation

Authors: Naito Ishimoto, Jae-Hyun Park, Kouki Kawakami, Michiko Tajiri, Kenji Mizutani, Satoko Akashi, Jeremy R H Tame, Asuka Inoue, Sam-Yong Park

Journal: Nat Commun

PubMed ID: 37433790

Doi: 10.1038/s41467-023-39799-2

Products & Services: Gene Synthesis

Spatially-Encoding Hydrogels With DNA to Control Cell Signaling

Authors: Namrata Ramani, C Adrian Figg, Alex J Anderson, Peter H Winegar, EunBi Oh, Sasha B Ebrahimi, Devleena Samanta, Chad A Mirkin

Journal: Adv Mater

PubMed ID: 37221642

Doi: 10.1002/adma.202301086

Products & Services: Recombinant Proteins

Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor

Authors: Wan Ni Chia, Chee Wah Tan, Aaron Wai Kit Tan, Barnaby Young, Tyler N Starr, Ester Lopez, Guntur Fibriansah, Jennifer Barr, Samuel Cheng, Aileen Ying-Yan Yeoh, Wee Chee Yap, Beng Lee Lim, Thiam-Seng Ng, Wan Rong Sia, Feng Zhu, Shiwei Chen, Jinyan Zhang, Madeline Sheng Si Kwek, Allison J Greaney, Mark Chen, Gough G Au, Prasad N Paradkar, Malik Peiris, Amy W Chung, Jesse D Bloom, David Lye, Sheemei Lok, Lin-Fa Wang

Journal: Sci Adv

PubMed ID: 37494438

Doi: 10.1126/sciadv.ade3470

Products & Services: Protein and Antibody Isolation

Role and neural regulation of clock genes in the rat pineal gland: Clock modulates amplitude of rhythmic expression of Aanat encoding the melatonin-producing enzyme

Authors: Aurea S Blancas-Velazquez, Tenna Bering, Signe Bille, Martin F Rath

Journal: J Pineal Res

PubMed ID: 37349875

Doi: 10.1111/jpi.12893

Products & Services: Protein and Antibody Isolation

Histone deacetylase III interactions with BK polyomavirus large tumor antigen may affect protein stability

Authors: Yueh-Han Hsu, Chun-Nun Chao, Hsin-Yi Huang, Pei-Wen Zhao, Pang-Hung Hsu, Cheng-Huang Shen, San-Yuan Chen, Chiung-Yao Fang