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ANovelDeNovoBiosyntheticPathwayforEfficientSynthesisof6′ SialyllactoseinEscherichiacoli

Authors: Manxiang Zhu,Hongzhi Xia, Xianhao Xu, Yanfeng Liu, Guocheng Du,XuKueqin Lv, Long Liu, Shixiu Cui, Jianghua Li, and Yingyue Li

Journal: Synthetic Biology

Doi: 10.1021/acssynbio.5c00437

Products & Services: Gene Synthesis

Human endogenous retrovirus K (HERV-K) envelope structures in pre- and postfusion by cryo-EM

Authors: Jeremy Shek; Chen Sun; Elise M. Wilson; Fatemeh Moadab; Kathryn M. Hastie; Roshan R. Rajamanickam; Patrick J. Penalosa; Stephanie S. Harkins; Diptiben Parekh; Chitra Hariharan; Dawid S. Zyla; Cassandra Yu; Kelly C. L. Shaffer; Victoria I. Lewis; Ruben Diaz Avalos; Tomas Mustelin; Erica Ollmann Saphire

Journal: SCIENCE ADVANCES

PubMed ID: 40864726

Doi: 10.1126/sciadv.ady8168

Products & Services: ELISA Kits

Polycystin-1 Mutant Alters Mechanotransduction in Response to Collagen and Extracellular Matrix Stiffness via Daam1-Dependent Microfilament Remodeling

Authors: Jiaofeng Zhou, Yibing Deng, Jie Mei, Mengyun Wan, Ningyi Xue, Xinyu Zong, Ji Zhou, Junli Ding, Ting Yan, Yu Jiang, Tiansong Xia, Peng Zheng, Yichao Zhu

Journal: Advanced Science

PubMed ID: 40789101

Doi: 10.1002/advs.202509846

Products & Services: Mutagenesis Services

Impaired mitochondria-initiated crosstalk with lysosomes reciprocally aggravates mitochondrial defect through LManVI

Authors: Shengnan Li, Zhaoliang Shan, Guochun Zhao, Yuwei Li, Minghui Du, Xiuxiu Ti, Yuxue Gao, Wenting Li, Hui Zuo, Yan Wang, Qing Zhang

Journal: Nature Communications

PubMed ID: 40774949

Doi: 10.1038/s41467-025-62147-5.

Products & Services: Catalog Antibodies

Helicobacter hepaticus promotes hepatic steatosis through CdtB-induced mitochondrial stress and lipid metabolism reprogramming

Authors: Shanhao Jin, Liqi Zhu, Ruoyu Bao, Linghan Yang, Tinglong Zhuang, Liyou Lian, Tao Wang, Jun Yin, Shilei Zhang, Lei Zhou, Minghua Zheng, Quan Zhang

Journal: Nature Communications

PubMed ID: 40858606

Doi: 10.1038/s41467-025-63351-z.

Products & Services: Protein and Antibody Isolation

Mesothelin-directed protein-drug conjugates for mesothelin-low solid tumor therapy

Authors: Ying Wang, Jiayao Yan, Lin Li, Tianran Chen, Jingyi Guo, Lei Lei, Siwen Wu, Lijing Zhu, Xiaotong Chen, Baorui Liu

Journal: Nature Communications

PubMed ID: 40849430

Doi: 10.1038/s41467-025-63269-6.

Products & Services: Recombinant Proteins

Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious

Authors: Jiří Holoubek, Jiří Salát, Milos Matkovic, Petr Bednář, Pavel Novotný, Martin Hradilek, Taťána Majerová, Ebba Rosendal, Luděk Eyer, Andrea Fořtová, Michaela Beránková, Lesley Bell-Sakyi, Anna K. Överby, Andrea Cavalli, Massimiliano Bonomi, Félix A. Rey, Daniel Růžek

Journal: Nature Communications

PubMed ID: 40796726

Doi: 10.1038/s41467-025-62750-6.

Products & Services: PCR Cloning and Subcloning

The cAMP-PKA signaling initiates mitosis by phosphorylating Bora

Authors: Min Zhu, Shinan Zhou, Yingqi Zhang, Qinfu Chen, Xueying Yuan, Long Zhang, Haiyan Yan, Fangwei Wang

Journal: Nature Communications

PubMed ID: 40849432

Doi: 10.1038/s41467-025-63352-y.

Products & Services: Polyclonal Antibody Services

Soluble N-terminal region of prion protein causes rapid neurodegeneration in prion disease

Authors: Runchuan Yan, Yan Zhang, Jingjing Zhang, Xiangyi Zhang, Yue Han, Mengfei Wang, Dan Wang, Shengnan Huang, Wei Liu, Qi Shi, Xiaoping Dong, Wen-Quan Zou, Zhen Li, Jiyan Ma

Journal: SCIENCE ADVANCES

PubMed ID: 40768577

Doi: 10.1126/sciadv.adw6867

Products & Services: Recombinant Antibody Expression

Structural insights into polymerase-catalyzed FAD capping of hepatitis C virus RNA

Authors: De-Ping Wang, Rong Zhao, Wen-Shu Hu, Hai-Ning Li, Ji-Min Cao, Xin Zhou, Ye Xiang

Journal: Nature Communications

PubMed ID: 40775214

Doi: 10.1038/s41467-025-62609-w.

Products & Services: Protein and Antibody Isolation