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4D structural biology-quantitative dynamics in the eukaryotic RNA exosome complex

Authors: Jobst Liebau, Daniela Lazzaretti, Torben Fürtges, Anna Bichler, Michael Pilsl, Till Rudack, Remco Sprangers

Journal: Nature Communications

PubMed ID: 40849410

Doi: 10.1038/s41467-025-62982-6.

Products & Services: Codon Optimization

Vortex-Generated Microdroplets Enable Simple, Rapid, and Low-Volume Measurement of Condensate Volume and Concentration

Authors: Feipeng Chen, Ho Cheung Shum

Journal: Advanced Science

PubMed ID: 40841927

Doi: 10.1002/advs.202511197

Products & Services: Catalog Peptides

Nascent liver proteome reveals enzymes and transcription regulators under physiological and alcohol exposure conditions

Authors: Jiayu Gu, Lihui Lao, Linzhen Hu, Jia Zang, Chao Liu, Ruixi Wan, Ling Tang, Ying Yuan, Yulin Chen, Shixian Lin

Journal: Nature Communications

PubMed ID: 40858584

Doi: 10.1038/s41467-025-63212-9.

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Heme allocation in eukaryotic cells relies on mitochondrial heme export through FLVCR1b to cytosolic GAPDH

Authors: Dhanya Thamaraparambil Jayaram, Pranav Sivaram, Pranjal Biswas, Yue Dai, Elizabeth A Sweeny, Dennis J Stuehr

Journal: Nature Communications

PubMed ID: 40858607

Doi: 10.1038/s41467-025-62819-2.

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Epsin1 enforces a condensation-dependent checkpoint for ubiquitylated cargo during clathrin-mediated endocytosis

Authors: Susovan Sarkar, Hao-Yang Liu, Feng Yuan, Brandon T Malady, Liping Wang, Eileen M Lafer, Jessica Perez, Jon M Huibregtse, Jeanne C Stachowiak

Journal: Nature Communications

PubMed ID: 40854908

Doi: 10.1038/s41467-025-63238-z.

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Standardizing a Protocol for Streamlined Synthesis and Characterization of Lipid Nanoparticles to Enable Preclinical Research and Education

Authors: Shilpi Agrawal, Abbey L Stokes, Christopher E Nelson

Journal: biorxiv

PubMed ID: 40766677

Doi: 10.1101/2025.07.31.667476

Products & Services: Catalog IVT RNA products

Proteolysis-triggered RNA Interference for Mitochondrial Iron Dyshomeostasis to Activate Antitumor Immunity in Hepatic Carcinoma

Authors: Shi-Man Zhang, Xiao-Kang Jin, Hong Chen, Yu-Zhang Wang, Jun-Long Liang, Jun Feng, Wei-Hai Chen, Xian-Zheng Zhang

Journal: ADVANCED MATERIALS

PubMed ID: 40757917

Doi: 10.1002/adma.202508457

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Anti-PS IgG Immune Complexes Impair Macrophage Phagocytosis in SLE via LOX-Dependent Oxidative Stress

Authors: Hui Guan, Liqi Huang, Yu Liu, Enyi Zhu, Lefeng Chen, Weijie Li, Haiqi Wu, Xiaoying Zhang, Rencai Qin, Jingpeng Zheng, Yingqian Mo, Ming Zhong, Bihua Xu, Xiaoyan Dai, Qi Wei, Yunwei Chen, Qingwen Wang, Zhihua Zheng, Kongyang Ma, Chun Tang

Journal: Journal of Inflammation Research

PubMed ID: 106070

Products & Services: Endotoxin Detection & Removal System

Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy

Authors: Zeguang Wu, Jinhong Shi, Qiezhong Lamao, Yuanyuan Qiu, Jinxin Yang, Yang Liu, Feifei Liang, Xue Sun, Wei Tang, Changya Chen, Qingming Yang, Chunmeng Wang, Zhifang Li, Haixia Zhang, Zhonghan Yang, Yunyi Zhang, Yuting Yi, Xufen Zheng, Yu Sun, Kuiying Ma, Lingling Yu, Huihui Yang, Zhaoxuan Wang, Wenjuan Zheng, Ling Yang, Zhixuan Zhang, Yongjian Zhang, Zhiqiang Wu, Yao Wang, Catherine C L Wong, Ming Jin, Pengfei Yuan, Weidong Han, Wensheng Wei

Journal: Cell

PubMed ID: 40845838

Doi: doi.org/10.1016/j.cell.2025.07.046

Products & Services: Synthetic Guide RNA

A Bivalent mRNA Vaccine Efficiently Prevents Gammaherpesvirus Latent Infection

Authors: Yannan Yin, Jinkai Zang, Huichun Shi, Zhuang Wang, Linlin Kuang, Shuxia Wang, Haikun Wang, Ning Li, Xiaozhen Liang, Zhong Huang

Journal: Vaccines

PubMed ID: 40872916

Products & Services: Gene Synthesis