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Functional Diversity of Homologous Oxidoreductases-Tuning of Substrate Specificity by a FAD-Stacking Residue for Iron Acquisition and Flavodoxin Reduction

Authors: Marta Hammerstad, Anne Kristine Rugtveit, Sondov Dahlen, Hilde Kristin Andersen, Hans-Petter Hersleth

Journal: Antioxidants (Basel)

PubMed ID: 37371954

Doi: 10.3390/antiox12061224

Products & Services: Gene Synthesis

A bioengineered pseudovirus nanoparticle displaying SARS-CoV 2 RBD fully protects mice from mortality and weight loss caused by SARS-CoV 2 challenge

Authors: Ming Xia, Krisangel López, Frank S Vago, Pengwei Huang, Dawn I Auguste, Wen Jiang, Albert J Auguste, Ming Tan

Journal: Biotechnol J

PubMed ID: 37300425

Doi: 10.1002/biot.202300130

Products & Services: Molecular Biology Reagents

Folding Double-Stranded DNA into Designed Shapes with Triplex-Forming Oligonucleotides

Authors: Cindy Ng , Anirban Samanta , Ole Aalund Mandrup , Emily Tsang , Sarah Youssef , Lasse Hyldgaard Klausen , Mingdong Dong , Minke A D Nijenhuis , Kurt V Gothelf

Journal: Adv Mater .

PubMed ID: 37311656

Doi: 10.1002/adma.202302497

Products & Services: DNA Sequencing

A mitotic NADPH upsurge promotes chromosome segregation and tumour progression in aneuploid cancer cells

Authors: Aoxing Cheng, Tian Xu , Weiyi You, Ting Wang, Dongming Zhang, Huimin Guo , Haiyan Zhang , Xin Pan , Yucai Wang , Liu Liu , Kaiguang Zhang , Jue Shi , Xuebiao Yao ， Jing Guo , Zhenye Yang

Journal: Nat Metab .

PubMed ID: 37349486

Doi: 10.1038/s42255-023-00832-9

Products & Services: Antibody Modification and Purification Services

Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos

Authors: Liang Chen, Mengjia Hong, Changming Luan, Hongyi Gao, Gaomeng Ru, Xinyuan Guo, Dujuan Zhang, Shun Zhang, Changwei Li, Jun Wu, Peyton B Randolph, Alexander A Sousa, Chao Qu, Yifan Zhu, Yuting Guan, Liren Wang, Mingyao Liu, Bo Feng, Gaojie Song, David R Liu, Dali Li

Journal: Nat Biotechnol

PubMed ID: 37322276

Doi: 10.1038/s41587-023-01821-9

Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models

Authors: Sujin Zhou, Yan Lin, Zhenggang Zhao, Yunhao Lai, Mengmeng Lu, Zishen Shao, Xinyu Mo, Yunping Mu, Zhipeng Liang, Xinxing Wang, Jingming Qu, Hua Shen, Fanghong Li, Allan Z Zhao

Journal: Cell Rep Med

PubMed ID: 37269826

Doi: 10.1016/j.xcrm.2023.101070

Products & Services: Custom Vector Construction

Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane

Authors: Wei Shi, Yongfei Cai, Haisun Zhu, Hanqin Peng, Jewel Voyer, Sophia Rits-Volloch, Hong Cao, Megan L Mayer, Kangkang Song, Chen Xu, Jianming Lu, Jun Zhang, Bing Chen

Journal: Nature

PubMed ID: 37285872

Doi: 10.1038/s41586-023-06273-4

Products & Services: Protein and Antibody Isolation

The role of mechano-regulated YAP/TAZ in erectile dysfunction

Authors: Mintao Ji, Dongsheng Chen, Yinyin Shu, Shuai Dong, Zhisen Zhang, Haimeng Zheng, Xiaoni Jin, Lijun Zheng, Yang Liu, Yifei Zheng, Wensheng Zhang, Shiyou Wang, Guangming Zhou, Bingyan Li, Baohua Ji, Yong Yang, Yongde Xu, Lei Chang

Journal: Nat Commun

PubMed ID: 37353497

Doi: 10.1038/s41467-023-39009-z

Products & Services: Protein Electrophoresis and Western

Genome-wide characterization of extrachromosomal circular DNA in gastric cancer and its potential role in carcinogenesis and cancer progression

Authors: Xianming Jiang, Xiaoguang Pan, Wenchao Li, Peng Han, Jiaying Yu, Jing Li, Haoran Zhang, Wei Lv, Ying Zhang, Yulong He, Xi Xiang

Journal: Cell Mol Life Sci

PubMed ID: 37369919

Doi: 10.1007/s00018-023-04838-0

Products & Services: Protein and Antibody Isolation

Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing

Authors: Hyatt Balke-Want, Vimal Keerthi, Nikolaos Gkitsas, Andrew G Mancini, Gavin L Kurgan, Carley Fowler, Peng Xu, Xikun Liu, Kyle Asano, Sunny Patel, Christopher J Fisher, Annie K Brown, Ramya H Tunuguntla, Shabnum Patel, Elena Sotillo, Crystal L Mackall, Steven A Feldman

Journal: Mol Cancer

PubMed ID: 37365642

Doi: 10.1186/s12943-023-01799-7

Products & Services: Protein and Antibody Isolation