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Electrochemical biosensor strategy combining DNA entropy-driven technology to activate CRISPR-Cas13a activity and triple-stranded nucleic acids to detect SARS-CoV-2 RdRp gene

Authors: Chenyi Zhuo, Zichun Song, Jiuying Cui, Yuanxun Gong, Qianli Tang, Kai Zhang, Xinlei Song, Xianjiu Liao

Journal: Mikrochim Acta

PubMed ID: 37351704

Doi: 10.1007/s00604-023-05848-2

Products & Services: Synthetic Guide RNA

Optimization of mammalian expression vector by cis-regulatory element combinations

Authors: Lu-Yu Zhou, Shuang Zhang, Li-Yun Li, Guo-Yu Yang, Lei Zeng

Journal: Mol Genet Genomics

PubMed ID: 37318628

Doi: 10.1007/s00438-023-02042-0

Products & Services: Gene Synthesis

miR‑124 inhibits cardiomyocyte apoptosis in myocardial ischaemia‑reperfusion injury by activating mitochondrial calcium uniporter regulator 1

Authors: Linlin Guo, Chaoying Liu, Chunyan Jiang, Yanhan Dong, Lynn Htet Htet Aung, Han Ding, Yanyan Gao

Journal: Mol Med Rep

PubMed ID: 37326122

Doi: 10.3892/mmr.2023.13031

Products & Services: Molecular Biology Reagents

Nullomer peptide increases immune cell infiltration and reduces tumor metabolism in triple negative breast cancer mouse model

Authors: Nilufar Ali, Cody Wolf, Swarna Kanchan, Shivakumar R Veerabhadraiah, Laura Bond, Matthew W Turner, Cheryl L Jorcyk, Greg Hampikian

Journal: Res Sq

PubMed ID: 37461536

Doi: 10.21203/rs.3.rs-3097552/v1

Products & Services: Peptide Synthesis

Lymphocyte infiltration and antitumoral effect promoted by cytotoxic inflammatory proteins formulated as self-assembling, protein-only nanoparticles

Authors: Carlos Martínez-Torró, Lorena Alba-Castellón, Luis Miguel Carrasco-Díaz, Naroa Serna, Laura Imedio, Alberto Gallardo, Isolda Casanova, Ugutz Unzueta, Esther Vázquez, Ramón Mangues, Antonio Villaverde

Journal: Biomed Pharmacother

PubMed ID: 37276641

Doi: 10.1016/j.biopha.2023.114976

Products & Services: Protein and Antibody Isolation

Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides

Authors: Xueli Cao, Yu Xiao, Erin Huiting, Xujun Cao, Dong Li, Jie Ren, Linlin Guan, Yu Wang, Lingyin Li, Joseph Bondy-Denomy, Yue Feng

Journal: biorxiv

PubMed ID: 37398474

Doi: 10.1101/2023.06.01.543220

Products & Services: Protein and Antibody Isolation

Photoperiod Induces DNA Methylation Changes in the Melatonin Receptor 1A Gene in Ewes

Authors: Xiaoyun He, Wei Wang, Wei Sun, Mingxing Chu

Journal: Animals (Basel)

PubMed ID: 37370427

Doi: 10.3390/ani13121917

Products & Services: Protein and Antibody Isolation

Three neutralizing mAbs induced by MPXV A29L protein recognizing different epitopes act synergistically against orthopoxvirus

Authors: Mengjun Li, Zuning Ren, Yuelin Wang, Yushan Jiang, Minghui Yang, Delin Li, Jiayin Chen, Zuxin Liang, Yuhao Lin, Zhujun Zeng, Rui Xu, Yiting Wang, Li Zhu, Weiwei Xiao, Qinghua Wu, Bao Zhang, Chengsong Wan, Yang Yang, Bo Wu, Jie Peng, Wei Zhao, Chenguang Shen

Journal: Emerging Microbes & Infections.

PubMed ID: 37288876

Doi: 10.1080/22221751.2023.2223669

Products & Services: Peptide Synthesis

Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis

Authors: Tian Xie , Peng Liu , Xinyue Wu , Feitong Dong, Zike Zhang, Jian Yue, Usha Mahawar, Faheem Farooq, Hisham Vohra, Qi Fang, Wenchen Liu, Binks W Wattenberg, Xin Gong

Journal: Nat Commun.

PubMed ID: 37308477

Doi: 10.1038/s41467-023-39274-y

Products & Services: Protein and Antibody Isolation

Persistent serum protein signatures define an inflammatory subcategory of long COVID

Authors: Aarthi Talla, Suhas V Vasaikar, Gregory Lee Szeto, Maria P Lemos, Julie L Czartoski, Hugh MacMillan, Zoe Moodie, Kristen W Cohen, Lamar B Fleming, Zachary Thomson, Lauren Okada, Lynne A Becker, Ernest M Coffey, Stephen C De Rosa, Evan W Newell, Peter J Skene, Xiaojun Li, Thomas F Bumol, M Juliana McElrath, Troy R Torgerson

Journal: Nat Commun

PubMed ID: 37296110

Doi: 10.1038/s41467-023-38682-4

Products & Services: Peptide Synthesis