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Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase

Authors: Joshua J Maw, Jesse A Coker, Tarun Arya, Christopher M Goins, Dhiraj Sonawane, Sang Hoon Han, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Nancy S Wang, Hannelore V Heemers, Jonathan D Macdonald, Shaun R Stauffer

Journal: J Med Chem

PubMed ID: 38330278

Doi: 10.1021/acs.jmedchem.3c01807

Products & Services: Custom Vector Construction

mTOR Regulates Mineralocorticoid Receptor Transcriptional Activity by ULK1-Dependent and -Independent Mechanisms

Authors: Yusuf Ali, Celso E Gomez-Sanchez, Maria Plonczynski, Aniko Naray-Fejes-Toth, Geza Fejes-Toth, Elise P Gomez-Sanchez

Journal: Endocrinology

PubMed ID: 38325289

Doi: 10.1210/endocr/bqae015

Products & Services: Protein and Antibody Isolation

Exploring the immunogenicity of Rv2201-519: A T-cell epitope-based antigen derived from Mycobacterium tuberculosis AsnB with implications for tuberculosis infection detection and vaccine development

Authors: Xiuli Luan, Xueting Fan, Guilian Li, Mchao Li, Na Li, Yuhan Yan, Xiuqin Zhao, Haican Liu, Kanglin Wan

Journal: Int Immunopharmacol

PubMed ID: 38342063

Doi: 10.1016/j.intimp.2024.111542

Products & Services: Molecular Biology Reagents

Bicistronic expression of nuclear transgenes in Chlamydomonas reinhardtii

Authors: Nick Jacobebbinghaus, Kyle J Lauersen, Olaf Kruse, Thomas Baier

Journal: The Plant Journal

PubMed ID: 38415961

Doi: 10.1111/tpj.16677

Products & Services: Gene Synthesis

Dissecting a two-domain alginate lyase of family PL6 reveals a mechanistic basis for substrate specificity and enzyme activity

Authors: Mikkel Madsen; Mette E. R nne; Agnes B. Petersen; Tobias Tandrup; Bo Pilgaard; Jesper Holck; Finn L. Aachmann; Casper Wilkens; Leesa J. Klau; Birte Svensson

Journal: The Journal of Biological Chemistry

PubMed ID: 41638429

Doi: 10.1016/j.jbc.2026.111227

Dissecting a two-domain alginate lyase of family PL6 reveals a mechanistic basis for substrate specificity and enzyme activity

Authors: Mikkel Madsen; Mette E. R nne; Agnes B. Petersen; Tobias Tandrup; Bo Pilgaard; Jesper Holck; Finn L. Aachmann; Casper Wilkens; Leesa J. Klau; Birte Svensson

Journal: The Journal of Biological Chemistry

PubMed ID: 41638429

Doi: 10.1016/j.jbc.2026.111227

SPR spectroscopic analysis of myosin binding to wild type and mutant UNC45B

Authors: Silvana Valdebenito, Eliseo Eugenin, Andres Oberhauser

Journal: MicroPubl Biol

PubMed ID: 38404916

Doi: 10.17912/micropub.biology.001131

Products & Services: Recombinant Proteins

Essential functions of Inositol hexakisphosphate (IP6) in Murine Leukemia Virus replication

Authors: Banhi Biswas, Kin Kui Lai, Harrison Bracey, Siddhartha A K Datta, Demetria Harvin, Gregory A Sowd, Christopher Aiken, Alan Rein

Journal: biorxiv

PubMed ID: 38464197

Doi: 10.1101/2024.02.27.581940

Products & Services: Protein and Antibody Isolation

An oncolytic virus–T cell chimera for cancer immunotherapy

Authors: Yuxuan Chen , Xiaohong Chen , Weier Bao , Gang Liu , Wei Wei , Yuan Ping

Journal: Nat Biotechnol .

PubMed ID: 38336902

Doi: 10.1038/s41587-023-02118-7

Products & Services: Recombinant Proteins

Distinct structural variants and repeat landscape shape the genomes of the ancient grapes Aglianico and Falanghina

Authors: Riccardo Aversano, Marina Iovene , Salvatore Esposito , Alberto L'Abbate , Clizia Villano , Ermanno Di Serio , Maria Francesca Cardone , Carlo Bergamini , Riccardo Aiese Cigliano , Vincenzo D'Amelia , Luigi Frusciante , Domenico Carputo

Journal: BMC Plant Biol.

PubMed ID: 38317087

Doi: 10.1186/s12870-024-04778-2

Products & Services: Custom DNA/RNA Oligos