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Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders

Authors: Saskia Hoffmann, Satyakrishna Pentakota, Andreas Mund, Peter Haahr, Fabian Coscia, Marta Gallo, Matthias Mann, Nicholas M. I. Taylor, Niels Mailand

Journal: biorxiv

Doi: 10.1101/2020.03.16.993600

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The KSHV ORF34 protein Interacts and Stabilizes HIF-2α via Binding to the HIF-2α bHLH and PAS Domains.

Authors: HaqueMuzammel，Kousoula

Journal: J. Virol.

PubMed ID: 31189709

Doi: 10.1128/JVI.00764-19

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Interaction and Regulation Between Lipid Mediator Phosphatidic Acid and Circadian Clock Regulators.

Authors: KimSang-Chul，NusinowDmitri A，SorkinMaria L，Pruneda-PazJose，WangXu

Journal: Plant Cell

PubMed ID: 30674693

Doi: 10.1105/tpc.18.00675

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Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1

Authors: Zhang J1, Ali AM2, Lieu YK3, Liu Z4, Gao J1, Rabadan R4, Raza A5, Mukherjee S6, Manley JL7.

Journal: Mol Cell.

PubMed ID: 31474574

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The Bromodomain Protein 4 Contributes to the Regulation of Alternative Splicing

Authors: Uppal S, Gegonne A, Chen Q, Thompson PS, Cheng D, Mu J, Meerzaman D, Misra HS, Singer DS

Journal: Cell Rep

PubMed ID: 31747612

Doi: 10.1016/j.celrep.2019.10.066

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PARP1 Suppresses the Transcription of PD-L1 by Poly(ADP-Ribosyl)ating STAT3.

Authors: DingLing，ChenXi，XuXiaqing，QianYuli，LiangGuikai，YaoFengqi，YaoZhangting，WuHonghai，ZhangJieqiong，HeQiaojun，Ya

Journal: Cancer Immunol Res

PubMed ID: 30401677

Doi: 10.1158/2326-6066.CIR-18-0071

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Identification of NMS-873， an allosteric and specific p97 inhibitor， as a broad antiviral against both influenza A and B viruses.

Authors: ZhangJiantao，HuYanmei，HauRaymond，MusharrafiehRami，MaChunlong，ZhouXu，ChenYin，Wan

Journal: Eur J Pharm Sci

PubMed ID: 30930289

Doi: 10.1016/j.ejps.2019.03.020

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LIR-dependent LMX1A/LMX1B autophagy crosstalk shapes human midbrain dopaminergic neuronal resilience

Authors: Natalia Jiménez-Moreno, Petros Stathakos, Zuriñe Antón, Deborah K. Shoemark, Richard B. Sessions, Ralph Witzgall, Maeve Caldwell, View Jon D. Lane

Journal: biorxiv

Doi: doi: 10.1101/636712

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UBIAD1 suppresses the proliferation of bladder carcinoma cells by regulating H-Ras intracellular trafficking via interaction with the C-terminal domain of H-Ras

Authors: Xu Z, Duan F, Lu H, Abdulkadhim Dragh M, Xia Y, Liang H, Hong L

Journal: Cell Death Dis

PubMed ID: 30518913

Doi: 10.1038/s41419-018-1215-4

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Itm2a silencing rescues lamin A mediated inhibition of 3T3-L1 adipocyte differentiation.

Authors: Davies Stephanie J，Ryan James，O'Connor Patrick B F，Kenny Elaine，Morris Derek，Baranov Pavel V，O'Connor Rosemary，McCarthy Tomm

Journal: Adipocyte

PubMed ID: 28872940

Doi: 10.1080/21623945.2017.1362510

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