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Transcription bodies regulate gene expression by sequestering CDK9

Authors: Martino Ugolini, Maciej A Kerlin, Ksenia Kuznetsova, Haruka Oda, Hiroshi Kimura, Nadine L Vastenhouw

Journal: Nature Cell Biology

PubMed ID: 38589534

Doi: 10.1038/s41556-024-01389-9

Products & Services: Custom DNA/RNA Oligos

Fuzzy recognition by the prokaryotic transcription factor HigA2 from Vibrio cholerae

Authors: San Hadži, Zala Živič , Matic Kovačič , Uroš Zavrtanik , Sarah Haeserts, Daniel Charlier, Janez Plavec, Alexander N Volkov, Jurij Lah, Remy Loris

Journal: Nature Communications

PubMed ID: 38600130

Doi: 10.1038/s41467-024-47296-3

Products & Services: PCR Cloning and Subcloning

Structural basis for dimerization of a paramyxovirus polymerase complex

Authors: Jin Xie, Mohamed Ouizougun-Oubari, Li Wang, Guanglei Zhai, Daitze Wu, Zhaohu Lin, Manfu Wang, Barbara Ludeke, Xiaodong Yan, Tobias Nilsson, Lu Gao, Xinyi Huang, Rachel Fearns, Shuai Chen

Journal: Nature Communications

PubMed ID: 38605025

Doi: 10.1038/s41467-024-47470-7

Products & Services: Protein and Antibody Isolation

SARS-CoV-2 nsp15 preferentially degrades AU-rich dsRNA via its dsRNA nickase activity

Authors: Xionglue Wang, Bin Zhu

Journal: Nucleic Acids Res

PubMed ID: 38634805

Doi: 10.1093/nar/gkae290

Products & Services: Custom DNA/RNA Oligos

RBM22 regulates RNA polymerase II 5' pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5

Authors: Xian Du, Wenying Qin, Chunyu Yang, Lin Dai, Mingkui San, Yingdan Xia, Siyu Zhou, Mengyang Wang, Shuang Wu, Shaorui Zhang, Huiting Zhou, Fangshu Li, Fang He, Jingfeng Tang, Jia-Yu Chen, Yu Zhou, Rui Xiao

Journal: Genome Biology

PubMed ID: 38641822

Doi: 10.1186/s13059-024-03242-6

Products & Services: Catalog Antibodies

Oncolytic adenovirus encoding apolipoprotein A1 suppresses metastasis of triple-negative breast cancer in mice

Authors: Jie Dong, Lingkai Kong, Shiqun Wang, Mao Xia, Yenan Zhang, Jingyi Wu, Fuming Yang, Shuguang Zuo, Jiwu Wei

Journal: Experimental & Clinical Cancer Research

PubMed ID: 38566092

Doi: 10.1186/s13046-024-03011-0

Products & Services: Catalog Antibodies

Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation

Authors: Miko aj S abicki; Jiho Park; Rados aw P. Nowak; Shourya S. Roy Burman; Jesse Pellman; Charles Zou; Hlib Razumkov; Jeannie Carreiro; Simran Rastogi; Anna Goldstein; Marek M. Nagiec; Katherine A. Donovan; Jianwei Che; Moritz Hunkeler; Qixiang Geng; Chi-Lin Hsu; Megha Lakshminarayan; Chelsea Shu; Rebecca L. Zon; Zuzanna Kozicka; Paul M.C. Park; Jonathan M. Tsai; Hojong Yoon; Lyn H. Jones; Adam S. Sperling; Nathanael S. Gray; Eric S. Fischer; Benjamin L. Ebert

Journal: Molecular Cell

PubMed ID: 40845806

Doi: 10.1016/j.molcel.2025.07.019

Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning

Authors: Gorka Lasso; Michael Grodus; Estefania Valencia; Veronica DeJesus; Eliza Liang; Isabel Delwel; Rob H. Bortz; Dmitry Lupyan; Hanna Y. Ehrlich; Adrian A. Castellanos; Andrea Gazzo; Heather L. Wells; Supaporn Wacharapluesadee; Alexandre Tremeau-Bravard; Janine F.R. Seetahal; Tom Hughes; Jimmy Lee; Mei-Ho Lee; Anna R. Sjodin; Marike Geldenhuys; Marinda Mortlock; Isamara Navarrete-Macias; Kirsten Gilardi; Michael R. Willig; Alessandra F.D. Nava; Elisabeth H. Loh; Makda Asrat; Tierra Smiley-Evans; Walter S. Magesa; Sijali Zikankuba; David Wolking; Gerardo Suz n; Rafael Ojeda-Flores; Christine V.F. Carrington; Ariful Islam; Jonathan H. Epstein; Wanda Markotter; Christine K. Johnson; Tracey Goldstein; Barbara A. Han; Jonna A.K. Mazet; Rohit K. Jangra; Kartik Chandran; Simon J. Anthony

Journal: Cell Host & Microbe

PubMed ID: 39818205

Doi: 10.1016/j.chom.2024.12.016

Products & Services: Protein and Antibody Isolation

CRISPR/CasΦ2-mediated gene editing in wheat and rye

Authors: Sanzeng Zhao , Xueying Han , Yachen Zhu , Yuwei Han , Huiyun Liu , Zhen Chen , Huifang Li , Dan Wang , Chaofan Tian , Yuting Yuan , Yajie Guo , Xiaomin Si , Daowen Wang, Xiang Ji

Journal: J Integr Plant Biol

PubMed ID: 38351739

Doi: 10.1111/jipb.13624

Products & Services: Synthetic Guide RNA

Bioactive fiber-reinforced hydrogel to tailor cell microenvironment for structural and functional regeneration of myotendinous junction

Authors: Yuzhi Sun 1, Renwang Sheng 2, Zhicheng Cao 1, Chuanquan Liu 2, Jiaxiang Li 1, Po Zhang 1, Yan Du 2, Qingyun Mo 2, Qingqiang Yao 1 3, Jialin Chen 2 3 4, Wei Zhang 2 3 4

Journal: Sci Adv

PubMed ID: 38657071

Doi: 10.1126/sciadv.adm7164

Products & Services: Recombinant Proteins