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Structural basis of regulated N-glycosylation at the secretory translocon

Authors: Melvin Yamsek, Mengxiao Ma, Roshan Jha, Yu Wan, Qianru Li, Frank Zhong, Katherine DeLong, Zhe Ji, Rajat Rohatgi, Robert J Keenan

Journal: Nature

PubMed ID: 41261126

Doi: 10.1038/s41586-025-09756-8.

Products & Services: Catalog Antibodies

ER protein CLCC1 promotes nuclear envelope fusion in herpesviral and host processes

Authors: Bing Dai, Adrian W Sperl, Lucas Polack, Isabel Mejia, Haley Dame, Tien Huynh, Chloe Deveney, Nathalie Lavoie, Chanyoung Lee, John G Doench, Matthew D Daugherty, Ekaterina E Heldwein

Journal: Nature Communications

PubMed ID: 41271665

Doi: 10.1038/s41467-025-65115-1.

Rational design of potent small-molecule SMARCA2/A4 degraders acting via the recruitment of FBXO22

Authors: Elisia Villemure, Tom Januario, Mingshuo Zeng, Hanna G Budayeva, Benjamin T Walters, Aaron Lictao, Ke Sherry Li, Xiaofen Ye, Caroline L Gilchrist, Bridget Hoag, Nicholas F Endres, Peter L Hsu, John Chan, Tommy K Cheung, Michael R Costa, Jean-Philippe Fortin, Noriko Ishisoko, Brett M Babin, Joyce Liu, Alexandra Frommlet, Joachim Rudolph, Robert L Yauch

Journal: Nature Communications

PubMed ID: 41184243

Doi: 10.1038/s41467-025-64669-4.

Latent-TGF-β has a domain swapped architecture

Authors: Mingliang Jin, Robert I Seed, Tiffany Shing, Li Wang, Junrui Li, Yifan Cheng, Stephen L Nishimura

Journal: Nature Communications

PubMed ID: 41290649

Doi: 10.1038/s41467-025-65465-w.

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Structural insight into bicarbonate-mediated carboxylation by human vitamin K-dependent carboxylase

Authors: Ke Wu, Zheng Wang, Deqiang Yao, Shaobai Li, Xiaozhu Wang, Yuanyuan Zhang, Mi Cao, Yafeng Shen, Shunpeng Xing, Jian Wu, Ming Lei, Pengfei Lan

Journal: Nature Communications

PubMed ID: 41290650

Doi: 10.1038/s41467-025-65488-3.

Products & Services: Protein and Antibody Isolation

Development of a cross-protective common cold coronavirus vaccine

Authors: Tanushree Dangi, Shiyi Li, Pablo Penaloza-MacMaster

Journal: Journal of virology

PubMed ID: 41123344

Doi: 10.1128/jvi.01526-25

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PCR-generated DNA templates enable efficient, rapid, and cost-effective mRNA synthesis

Authors: Naveen Kumar, Nicholas C Hazell, Jiani Bei, Tina Nguyen, Haitao Hu

Journal: Methods

PubMed ID: 40825451

Doi: 10.1016/j.ymeth.2025.08.007

Products & Services: PCR Cloning and Subcloning

De novo designed voltage-gated anion channels suppress neuron firing

Authors: Chen Zhou, Huican Li, Jiaxing Wang, Cheng Qian, Hui Xiong, Zhilin Chu, Qiming Shao, Xuan Li, Shijin Sun, Ke Sun, Aiqin Zhu, Jiawei Wang, Xueqin Jin, Fan Yang, Tamer M Gamal El-Din, Bo Li, Jing Huang, Kun Wu, Peilong Lu

Journal: Cell

PubMed ID: 41106381

Doi: 10.1016/j.cell.2025.09.023

Products & Services: Protein and Antibody Isolation

A novel low-cost and sensitive electrochemical biosensor based on Yb-protein/GO/SPE for rare earth element detection

Authors: Ting Zhang, Danni Ma, Jiaxing Gong, Bolun Sun, Fuman Cai

Journal: Sustainable Chemistry and Pharmacy

Doi: doi.org/10.1016/j.scp.2025.102248

Products & Services: Molecular Biology Reagents

Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity

Authors: Marta Alberti, Martina Tamburello, Stefano Salamone, Giorgio Gallinella, Cinzia Sanna, Giovanni Battista Appendino, Marco L Lolli, Alberto Massarotti, Federica Pollastro, Riccardo Miggiano

Journal: Journal of natural products

PubMed ID: 41143446

Doi: 10.1021/acs.jnatprod.5c00887

Products & Services: PCR Cloning and Subcloning