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Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers

Authors: Stephane Ferretti, Jacques Hamon, Ruben de Kanter, Clemens Scheufler，Henrik Möbitz, Marta Cortés-Cros

Journal: Nature

PubMed ID: 38658754

Doi: 10.1038/s41586-024-07350-y

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Transcription bodies regulate gene expression by sequestering CDK9

Authors: Martino Ugolini, Maciej A Kerlin, Ksenia Kuznetsova, Haruka Oda, Hiroshi Kimura, Nadine L Vastenhouw

Journal: Nature Cell Biology

PubMed ID: 38589534

Doi: 10.1038/s41556-024-01389-9

Products & Services: Custom DNA/RNA Oligos

Fuzzy recognition by the prokaryotic transcription factor HigA2 from Vibrio cholerae

Authors: San Hadži, Zala Živič , Matic Kovačič , Uroš Zavrtanik , Sarah Haeserts, Daniel Charlier, Janez Plavec, Alexander N Volkov, Jurij Lah, Remy Loris

Journal: Nature Communications

PubMed ID: 38600130

Doi: 10.1038/s41467-024-47296-3

Products & Services: PCR Cloning and Subcloning

Structural basis for dimerization of a paramyxovirus polymerase complex

Authors: Jin Xie, Mohamed Ouizougun-Oubari, Li Wang, Guanglei Zhai, Daitze Wu, Zhaohu Lin, Manfu Wang, Barbara Ludeke, Xiaodong Yan, Tobias Nilsson, Lu Gao, Xinyi Huang, Rachel Fearns, Shuai Chen

Journal: Nature Communications

PubMed ID: 38605025

Doi: 10.1038/s41467-024-47470-7

Products & Services: Protein and Antibody Isolation

SARS-CoV-2 nsp15 preferentially degrades AU-rich dsRNA via its dsRNA nickase activity

Authors: Xionglue Wang, Bin Zhu

Journal: Nucleic Acids Res

PubMed ID: 38634805

Doi: 10.1093/nar/gkae290

Products & Services: Custom DNA/RNA Oligos

RBM22 regulates RNA polymerase II 5' pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5

Authors: Xian Du, Wenying Qin, Chunyu Yang, Lin Dai, Mingkui San, Yingdan Xia, Siyu Zhou, Mengyang Wang, Shuang Wu, Shaorui Zhang, Huiting Zhou, Fangshu Li, Fang He, Jingfeng Tang, Jia-Yu Chen, Yu Zhou, Rui Xiao

Journal: Genome Biology

PubMed ID: 38641822

Doi: 10.1186/s13059-024-03242-6

Products & Services: Catalog Antibodies

Oncolytic adenovirus encoding apolipoprotein A1 suppresses metastasis of triple-negative breast cancer in mice

Authors: Jie Dong, Lingkai Kong, Shiqun Wang, Mao Xia, Yenan Zhang, Jingyi Wu, Fuming Yang, Shuguang Zuo, Jiwu Wei

Journal: Experimental & Clinical Cancer Research

PubMed ID: 38566092

Doi: 10.1186/s13046-024-03011-0

Products & Services: Catalog Antibodies

Artificial Extracellular Vesicles Generated from T Cells Using Different Induction Techniques

Authors: Ekaterina A Zmievskaya, Sabir A Mukhametshin, Irina A Ganeeva, Elvina M Gilyazova, Elvira T Siraeva, Marianna P Kutyreva, Artur A Khannanov, Youyong Yuan, Emil R Bulatov

Journal: Biomedicines

PubMed ID: 38672273

Doi: 10.3390/biomedicines12040919

Products & Services: Catalog Antibodies

Barley yellow dwarf virus-GAV 17K protein disrupts thiamine biosynthesis to facilitate viral infection in plants

Authors: Xiaoyu Han, Xue Yang, Siyu Chen, He Wang, Xiaomin Liu, Daowen Wang, Jin Yang, Linlin Chen, Bingjian Sun, Honglian Li, Yan Shi

Journal: Plant J

PubMed ID: 38635415

Doi: 10.1111/tpj.16772

Products & Services: Protein and Antibody Isolation

Multiplexed gene editing in citrus by using a multi-intron containing Cas9 gene

Authors: Poulami Sarkar, Jorge Santiago Vazquez, Mingxi Zhou, Amit Levy, Zhonglin Mou, Vladimir Orbović

Journal: Transgenic Res

PubMed ID: 38564120

Doi: 10.1007/s11248-024-00380-2