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Nuclear speckle proteins form intrinsic and MALAT1-dependent microphases

Authors: Min Kyung Shinn, Dylan T Tomares, Vicky Liu, Avnika Pant, Yuanxin Qiu, Andreas Vitalis, You Jin Song, Yuna Ayala, Kiersten M Ruff, Gregory W Strout, Matthew D Lew, Kannanganattu V Prasanth, Rohit V Pappu

Journal: Cell

PubMed ID: 41421357

Doi: 10.1016/j.cell.2025.11.026

Synthesis of Bispecific Conjugates by ADP-Ribosyl Cyclases

Authors: Sunny H Kim, Arshad J Ansari, Lei Zhang, Guoyun Kao, Thuc Oanh Hoang, Zeyu Zhang, Srinivasarao Singireddi, Benjamin B Katz, Yong Zhang

Journal: Advanced Science

PubMed ID: 41422434

Doi: 10.1002/advs.202518329

Products & Services: Protein and Antibody Isolation

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Authors: Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S L Parker, Yingying Guo, Dongming Zhou

Journal: Advanced Science

PubMed ID: 41431149

Doi: 10.1002/advs.202512262

Products & Services: Catalog Peptides

ApoE2-DARPin fusion proteins enable selective RNA transfer to CD8 T cells by lipid nanoparticles

Authors: Samuel A Theuerkauf, Luca J Zinser, Nandini Sheth, Elham Adabi, Lea R Knapp, Johanna M Gorol, Sascha Hein, Angeliki Chroni, Frederic B Thalheimer, Christian J Buchholz

Journal: Journal of controlled release

PubMed ID: 41197834

Doi: 10.1016/j.jconrel.2025.114377

Products & Services: Catalog IVT RNA products

Supramolecular lipid nanoparticle reprograms tumor microenvironment by cucurbit[7]uril-based host–guest recognition for STING-activating cancer immunotherapy

Authors: Yunxuan Feng, Yuan Yu, Xinyang Yu, Mengyao Li, Jiaqi Lei, Yongcan Li, Zhida Liu, Shaolong Qi, Guocan Yu

Journal: Materials Today

Doi: doi.org/10.1016/j.mattod.2025.11.029

Products & Services: Protein Electrophoresis and Western

OMP16-targeting monoclonal antibodies H4 and E6 reveal essential linear epitopes for Brucella immunoprotection

Authors: Yunyi Zhai, Kaihui Sun, Ye Yuan, Xiaofang Liu, Gaowa Wudong, Yuanhao Yang, Shuan Qu, Yaxin Li, Dong Zhou, Wei Liu, Yaping Jin, Aihua Wang

Journal: International Journal of Biological Macromolecules

PubMed ID: 41448303

Doi: 10.1016/j.ijbiomac.2025.149881

Products & Services: Bacterial Expression Mutagenesis Services Peptide Synthesis

Study on the phosphorylation of NAD+-specific isocitrate dehydrogenase in the pathogenic bacteria Stenotrophomonas maltophilia and Xanthomonas sacchari

Authors: Qian Tian, Yongmei Zhang, Chunxu Pan, Linxiao Wang, Na Qin, Zhen Jiang, Chenxi Li, Zhengyu Cao, Guoping Zhu, Peng Wang

Journal: Journal of enzyme inhibition and medicinal chemistry

PubMed ID: 41395810

Doi: 10.1080/14756366.2025.2593798

Products & Services: Gene Synthesis Codon Optimization

The ATPase activity of ABCB10 is modulated by conserved transmembrane arginine residues and by functional groups in the biliverdin molecule

Authors: Annabella Nouel Barreto, Valeria Arellano Haro, Alex L Hernandez, Maria E Zoghbi

Journal: Protein Science

PubMed ID: 41229075

Doi: 10.1002/pro.70366

Products & Services: Gene Synthesis Mutagenesis Services

Acyl-CoA-binding protein AcbdA is required for peroxisome hitchhiking on early endosomes in Aspergillus nidulans

Authors: Bellana E Driscoll, Madison B Fountain, Isabella N Gates, Reihane Abdollahi, Allison M Langley, Matthew B Owens, Jenna R Christensen, John Salogiannis

Journal: Molecular biology of the cell

PubMed ID: 40901736

Doi: 10.1091/mbc.e25-04-0186

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Molecular mechanism of PINK1 regulation by the Hsp90 machinery

Authors: Xuyang Tian, Jiayue Su, Ziyi Wang, Tao Liu, Huifang Xiong, Shan Sun, Kunrong Mei, Sen-Fang Sui

Journal: Nature Communications

PubMed ID: 41326378

Doi: 10.1038/s41467-025-65859-w.