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A gut microbiota-bile acid axis promotes intestinal homeostasis upon aspirin-mediated damage

Authors: Ting Li, Ning Ding, Hanqing Guo, Rui Hua, Zehao Lin, Huohuan Tian, Yue Yu, Daiming Fan, Zuyi Yuan, Frank J Gonzalez, Yue Wu

Journal: Cell Host & Microbe

PubMed ID: 38237593

Doi: 10.1016/j.chom.2023.12.015

Products & Services: Synthetic Guide RNA

A folate inhibitor exploits metabolic differences in Pseudomonas aeruginosa for narrow-spectrum targeting

Authors: Connor Chain, Joseph P Sheehan, Xincheng Xu, Soodabeh Ghaffari, Aneesh Godbole, Hahn Kim, Joel S Freundlich, Joshua D Rabinowitz, Zemer Gitai

Journal: Nature Microbiology

PubMed ID: 38594311

Doi: 10.1038/s41564-024-01665-2

Products & Services: Antibody Modification and Purification Services

Comparison of antibody-based immunotherapeutics for malignant hematological disease in an experimental murine model

Authors: Karin Frebel, Jörn C Albring, Anika Wohlgemuth, Christian Schwöppe, Stephan Hailfinger, Georg Lenz, Matthias Stelljes

Journal: Blood

PubMed ID: 38197968

Doi: 10.1182/bloodadvances.2023011647

Products & Services: Molecular Biology Reagents

A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria

Authors: Nicolas Grosjean, Estella F Yee, Desigan Kumaran, Kriti Chopra, Macon Abernathy, Sandeep Biswas, James Byrnes, Dale F Kreitler, Jan-Fang Cheng, Agnidipta Ghosh, Steven C Almo, Masakazu Iwai, Krishna K Niyogi, Himadri B Pakrasi, Ritimukta Sarangi, Hubertus van Dam, Lin Yang, Ian K Blaby, Crysten E Blaby-Haas

Journal: Nature Communications

PubMed ID: 38609367

Doi: 10.1038/s41467-024-47486-z

Products & Services: Protein and Antibody Isolation

Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade

Authors: Hao Nie, Pratima Saini, Taito Miyamoto, Liping Liao, Rafal J Zielinski, Heng Liu, Wei Zhou, Chen Wang, Brennah Murphy, Martina Towers, Tyler Yang, Yuan Qi, Toshitha Kannan, Andrew Kossenkov, Hiroaki Tateno, Daniel T Claiborne, Nan Zhang, Mohamed Abdel-Mohsen, Rugang Zhang

Journal: Nature Communications

PubMed ID: 38565883

Doi: 10.1038/s41467-024-47069-y

Products & Services: Gene Synthesis

Somatic and intergenerational G4C2 hexanucleotide repeat instability in a human C9orf72 knock-in mouse model

Authors: Nada Kojak, Junko Kuno, Kristina E Fittipaldi, Ambereen Khan, David Wenger, Michael Glasser, Roberto A Donnianni, Yajun Tang, Jade Zhang, Katie Huling, Roxanne Ally, Alejandro O Mujica, Terrence Turner, Gina Magardino, Pei Yi Huang, Sze Yen Kerk, Gustavo Droguett, Marine Prissette, Jose Rojas, Teodoro Gomez, Anthony Gagliardi, Charleen Hunt, Jeremy S Rabinowitz, Guochun Gong, William Poueymirou, Eric Chiao, Brian Zambrowicz, Chia-Jen Siao, Daisuke Kajimura

Journal: Nucleic Acids Res

PubMed ID: 38597682

Doi: 10.1093/nar/gkae250

Products & Services: PCR Cloning and Subcloning

Human inherited PD-L1 deficiency is clinically and immunologically less severe than PD-1 deficiency

Authors: Matthew B Johnson, Masato Ogishi, Clara Domingo-Vila, Elisa De Franco, Matthew N Wakeling, Zineb Imane, Brittany Resnick, Evangelia Williams, Rui Pedro Galão, Richard Caswell, James Russ-Silsby, Yoann Seeleuthner , Darawan Rinchai, Iris Fagniez, Basilin Benson, Matthew J Dufort, Cate Speake , Megan E Smithmyer, Michelle Hudson, Rebecca Dobbs; EXE-T1D consortium; Zoe Quandt, Andrew T Hattersley ,Peng Zhang, Stephanie Boisson-Dupuis , Mark S Anderson, Jean-Laurent Casanova, Timothy I Tree, Richard A Oram

Journal: Journal Of Experimental Medicine

PubMed ID: 38634869

Doi: 10.1084/jem.20231704

Products & Services: Catalog Antibodies

Energy metabolism as therapeutic target for aged wound repair by engineered extracellular vesicle

Authors: Yu Zhuang , Shengjie Jiang , Xiaoling Deng , An Lao , Xiaolin Hua , Yun Xie , Lingyong Jiang , Xudong Wang , Kaili Lin

Journal: SCIENCE ADVANCES

PubMed ID: 38608014

Doi: 10.1126/sciadv.adl0372

Products & Services: Protein and Antibody Isolation

The SARS-CoV-2 Spike Protein Receptor-Binding Domain Expressed in Rice Callus Features a Homogeneous Mix of Complex-Type Glycans

Authors: Guillermo Sobrino-Mengual, Victoria Armario-Nájera, Juliette Balieu, Marie-Laure Walet-Balieu, Andrea Saba-Mayoral, Ana M Pelacho, Teresa Capell, Paul Christou, Muriel Bardor, Patrice Lerouge

Journal: Int J Mol Sci

PubMed ID: 38674051

Doi: 10.3390/ijms25084466

Products & Services: Codon Optimization

Mutation of the peptide-regulated transcription factor ComR for amidated peptide specificity and heterologous function in WCFS1

Authors: Michael Brasino, Eli Wagnell, E Sila Ozdemir, Srivathsan Ranganathan, Justin Merritt

Journal: Microbiol Spectr

PubMed ID: 38687019

Doi: 10.1128/spectrum.00517-24

Products & Services: Gene Synthesis