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A fluorescence-based assay for measuring polyamine biosynthesis aminopropyl transferase mediated catalysis

Authors: Pallavi Singh; Jae-Yeon Choi; Weiwei Wang; Tukiet T. Lam; Philip Lechner; Christopher D. Vanderwal; Sovitj Pou; Aaron Nilsen; Choukri Ben Mamoun

Journal: The Journal of Biological Chemistry

PubMed ID: 39342998

Doi: 10.1016/j.jbc.2024.107832

A fluorescence-based assay for measuring polyamine biosynthesis aminopropyl transferase mediated catalysis

Authors: Pallavi Singh; Jae-Yeon Choi; Weiwei Wang; Tukiet T. Lam; Philip Lechner; Christopher D. Vanderwal; Sovitj Pou; Aaron Nilsen; Choukri Ben Mamoun

Journal: The Journal of Biological Chemistry

PubMed ID: 39342998

Doi: 10.1016/j.jbc.2024.107832

Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells

Authors: Mattijs Bulcaen; Ph line Kortleven; Ronald B. Liu; Giulia Maule; Elise Dreano; Mairead Kelly; Marjolein M. Ensinck; Sam Thierie; Maxime Smits; Matteo Ciciani; Aurelie Hatton; Benoit Chevalier; Anabela S. Ramalho; Xavier Casadevall i Solvas; Zeger Debyser; Fran ois Vermeulen; Rik Gijsbers; Isabelle Sermet-Gaudelus; Anna Cereseto; Marianne S. Carlon

Journal: Cell Reports Medicine

PubMed ID: 38697102

Doi: 10.1016/j.xcrm.2024.101544

Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells

Journal: Cell Reports Medicine

PubMed ID: 38697102

Doi: 10.1016/j.xcrm.2024.101544

Generative -hairpin design using a residue-based physicochemical property landscape

Authors: Vardhan Satalkar; Gemechis D. Degaga; Wei Li; Yui Tik Pang; Andrew C. McShan; James C. Gumbart; Julie C. Mitchell; Matthew P. Torres

Journal: Biophysical Journal

PubMed ID: 38297834

Doi: 10.1016/j.bpj.2024.01.029

Products & Services: Peptide Synthesis

Generative -hairpin design using a residue-based physicochemical property landscape

Authors: Vardhan Satalkar; Gemechis D. Degaga; Wei Li; Yui Tik Pang; Andrew C. McShan; James C. Gumbart; Julie C. Mitchell; Matthew P. Torres

Journal: Biophysical Journal

PubMed ID: 38297834

Doi: 10.1016/j.bpj.2024.01.029

Products & Services: Peptide Synthesis

Generative -hairpin design using a residue-based physicochemical property landscape

Authors: Vardhan Satalkar; Gemechis D. Degaga; Wei Li; Yui Tik Pang; Andrew C. McShan; James C. Gumbart; Julie C. Mitchell; Matthew P. Torres

Journal: Biophysical Journal

PubMed ID: 38297834

Doi: 10.1016/j.bpj.2024.01.029

Products & Services: Peptide Synthesis

De Novo Multi Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Authors: Xiaojuan Li; Haifan Gong; Yue Wang; Yinuo Zhao; Lixiang Li; Peijing Bao; Qingzhou Kong; Jialu Fu; Boyao Wan; Yumeng Zhang; Jinghui Zhang; Jiekun Ni; Zhongxue Han; Xueping Nan; Kunping Ju; Longfei Sun; Yuerui Ma; Huijun Chang; Mengqi Zheng; Yanbo Yu; Xiaoyun Yang; Xiuli Zuo; Haina Wang; Yanqing Li

Journal: Advanced Science

PubMed ID: 41801219

Doi: 10.1002/advs.202515835

Products & Services: Peptide Synthesis

SIRT2-mediated deacetylation of LCK governs the magnitude of T cell receptor signaling

Authors: Imene Hamaidi; Pingyan Cheng; Soo Young Jun; Alak Manna; Min-Hsuan Wang; Anh Nguyen; Ismail Can; Min G. Zhang; Odesha O. Taylor; Luis Uriel Lopez Bailon; Bin Fang; Bradford Perez; Ben C. Creelan; Andriy Marusyk; Dongjun Shin; Tae Hyun Hwang; Anders E. Berglund; Virginia S. Shapiro; Haitao M. Ji; Jos R. Conejo-Garcia; Sungjune Kim

Journal: nature immunology

PubMed ID: 41611868

Doi: 10.1038/s41590-025-02377-3

Products & Services: Custom Vector Construction

Structure-guided design of endosomolytic chloroquine-like lipid nanoparticles for mRNA delivery and genome editing

Authors: Zhen Liu, Jiacai Wu, Ning Wang, Yongqi Lin, Ruiteng Song, Min Zhang, Bin Li

Journal: Nature Communications

PubMed ID: 40335474

Doi: 10.1038/s41467-025-59501-y

Products & Services: Custom RNAi Services