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Human DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation
Authors: Natália C Moreno, Emilie J Korchak, Marcela T Latancia, Dana A D'Orlando, Temidayo Adegbenro, Ryan P Barnes, Irina Bezsonova, Roger Woodgate, Nicholas W Ashton
Journal: Nucleic Acids Research
PubMed ID: 41693564
Doi: 10.1093/nar/gkag098
The CXCL8/MAPK/hnRNP-K axis enables susceptibility to infection by EV-D68, rhinovirus, and influenza virus in vitro
Authors: Qingran Yang, Haoran Guo, Huili Li, Zhaoxue Li, Fushun Ni, Zhongmei Wen, Kai Liu, Huihui Kong, Wei Wei
Journal: Nature Communications
PubMed ID: 39962077
Doi: 10.1038/s41467-025-57094-0
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Discovery of a 6-Aminobenzo[ b ]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities
Authors: Patrik Oleksak; David Rysanek; Marketa Vancurova; Pavla Vasicova; Alexandra Urbancokova; Josef Novak; Dominika Maurencova; Pavel Kashmel; Jana Houserova; Romana Mikyskova; Ondrej Novotny; Milan Reinis; Pavel Juda; Miroslav Hons; Jirina Kroupova; David Sedlak; Tetyana Sulimenko; Pavel Draber; Marketa Chlubnova; Eugenie Nepovimova; Kamil Kuca; Miroslav Lisa; Rudolf Andrys; Tereza Kobrlova; Ondrej Soukup; Jiri Janousek; Lukas Prchal; Jiri Bartek; Kamil Musilek; Zdenek Hodny
Journal: ACS pharmacology & translational science
PubMed ID: 39296273
Doi: 10.1021/acsptsci.4c00190
Products & Services: Monoclonal Antibody Services   
Discovery of a 6-Aminobenzo[ b ]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities
Authors: Patrik Oleksak; David Rysanek; Marketa Vancurova; Pavla Vasicova; Alexandra Urbancokova; Josef Novak; Dominika Maurencova; Pavel Kashmel; Jana Houserova; Romana Mikyskova; Ondrej Novotny; Milan Reinis; Pavel Juda; Miroslav Hons; Jirina Kroupova; David Sedlak; Tetyana Sulimenko; Pavel Draber; Marketa Chlubnova; Eugenie Nepovimova; Kamil Kuca; Miroslav Lisa; Rudolf Andrys; Tereza Kobrlova; Ondrej Soukup; Jiri Janousek; Lukas Prchal; Jiri Bartek; Kamil Musilek; Zdenek Hodny
Journal: ACS pharmacology & translational science
PubMed ID: 39296273
Doi: 10.1021/acsptsci.4c00190
Products & Services: Monoclonal Antibody Services   
Zinc Influx Restricts Enterovirus D68 Replication
Authors: Shunan Liu, Xia Cao, Haoran Guo, Wei Wei
Journal: Front Microbiol
PubMed ID: 34721351
Doi: 10.3389/fmicb.2021.748546
Products & Services: Monoclonal Antibody Services   
Divergent regulation of inflammatory cytokines by mTORC1 in THP-1-derived macrophages and intestinal epithelial Caco-2 cells
Authors: Harleen Kaur, Anjeza Erickson, Régis Moreau
Journal: Life Sci
PubMed ID: 34478760
Doi: 10.1016/j.lfs.2021.119920
A novel transcriptional complex on the VE-cadherin promoter regulated the downregulation of VE-cadherin in the Down Syndrome Candidate Region 1 isoform 1L-mediated angiogenesis
Authors: Shiqiang Hou, Gengming Niu, Xin Liu, Pierre M Bourbon, Dongmei Zhang, Pengfei Cui, Kevin Zhao, Dezheng Zhao, Huiyan Zeng
Journal: Microvasc Res
PubMed ID: 34146582
Doi: 10.1016/j.mvr.2021.104209
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Glutaminolysis is involved in the activation of mTORC1 in in vitro-produced porcine embryos
Authors: Paula R Chen, Caroline G Lucas, Lee D Spate, Randall S Prather
Journal: Mol Reprod Dev
PubMed ID: 34075648
Doi: 10.1002/mrd.23516
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Autophagy-Dependent Increased ADAM10 Mature Protein Induced by TFEB Overexpression Is Mediated Through PPARα
Authors: Hongjie Wang, Mohan Kumar Muthu Karuppan, Madhavan Nair, Madepalli K Lakshmana
Journal: Mol Neurobiol
PubMed ID: 33417226
Doi: 10.1007/s12035-020-02230-8
Products & Services: Monoclonal Antibody Services   
Androgen receptor signaling regulates the transcriptome of prostate cancer cells by modulating global alternative splicing
Authors: Shah K,Gagliano T,Garland L,O'Hanlon T,Bortolotti D,Gentili V,Rizzo R,Giamas G,Dean M
Journal: Oncogene
PubMed ID: 32820253
Doi: 10.1038/s41388-020-01429-2
Products & Services: Recombinant Proteins   
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