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Prior infection and age impacts antibody persistence after SARS-CoV-2 mRNA vaccine

Authors: Elizabeth Fraley, Cas LeMaster, Santosh Khanal, Dithi Banerjee, Tomi Pastinen, Elin Grundberg, Rangaraj Selvarangan, Todd Bradley

Journal: Clin Infect Dis

PubMed ID: 34551091

Doi: 10.1093/cid/ciab850

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Monophosphoryl Lipid A and Poly I:C Combination Adjuvant Promoted Ovalbumin-Specific Cell Mediated Immunity in Mice Model

Authors: So Yeon Ahn, Chau Thuy Tien Le, Eun-Ju Ko

Journal: Biology (Basel)

PubMed ID: 34571785

Doi: 10.3390/biology10090908

Products & Services: Recombinant Proteins

Marburg and Ebola Virus mRNA 3' Untranslated Regions Contain Negative Regulators of Translation That Are Modulated by ADAR1 Editing

Authors: Sudip Khadka, Caroline G Williams, Joyce Sweeney-Gibbons, Christopher F Basler

Journal: J Virol

PubMed ID: 34346762

Doi: 10.1128/JVI.00652-21

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Antibody-dependent cellular cytotoxicity response to SARS-CoV-2 in COVID-19 patients

Authors: Yuanling Yu, Meiyu Wang, Xiaoai Zhang, Shufen Li, Qingbin Lu, Haolong Zeng, Hongyan Hou, Hao Li, Mengyi Zhang, Fei Jiang, Jiajing Wu, Ruxia Ding, Zehua Zhou, Min Liu, Weixue Si, Tao Zhu, Hangwen Li, Jie Ma, Yuanyuan Gu, Guangbiao She, Xiaokun Li, Yulan Zhang, Ke Peng, Weijin Huang, Wei Liu, Youchun Wang

Journal: Signal Transduct Target Ther

PubMed ID: 34561414

Doi: 10.1038/s41392-021-00759-1

Products & Services: Mammalian Expression

Hinge influences in murine IgG binding to Cryptococcus neoformans capsule

Authors: Diane Sthefany Lima de Oliveira, Verenice Paredes, Adrielle Veloso Caixeta, Nicole Moreira Henriques, Maggie P Wear, Patrícia Albuquerque, Maria Sueli Soares Felipe, Arturo Casadevall, André Moraes Nicola

Journal: Immunology

PubMed ID: 34458991

Doi: 10.1111/imm.13411

Products & Services: Recombinant Antibody Expression

Molecular and Enzymatic Characterization of Flavonoid 3'-Hydroxylase of ×

Authors: Julia Weissensteiner, Christian Molitor, Silvija Marinovic, Lisa Führer, Syed Waqas Hassan, Olly Sanny Hutabarat, Andreas Spornberger, Karl Stich, Johanna Hausjell, Oliver Spadiut, Christian Haselmair-Gosch, Heidi Halbwirth

Journal: Plants (Basel)

PubMed ID: 34579488

Doi: 10.3390/plants10091956

Products & Services: Molecular Biology Tools

Novel Antimicrobial Peptides from a Cecropin-Like Region of Heteroscorpine-1 from Venom with Membrane Disruption Activity

Authors: Rima Erviana, Yutthakan Saengkun, Prapenpuksiri Rungsa, Nisachon Jangpromma, Patcharaporn Tippayawat, Sompong Klaynongsruang, Jureerut Daduang, Sakda Daduang

Journal: Molecules

PubMed ID: 34641415

Doi: 10.3390/molecules26195872

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Tissue-Resident-Memory CD8 T Cells Bridge Innate Immune Responses in Neighboring Epithelial Cells to Control Human Genital Herpes

Authors: Tao Peng, Khamsone Phasouk, Catherine N Sodroski, Sijie Sun, Yon Hwangbo, Erik D Layton, Lei Jin, Alexis Klock, Kurt Diem, Amalia S Magaret, Lichen Jing, Kerry Laing, Alvason Li, Meei-Li Huang, Max Mertens, Christine Johnston, Keith R Jerome, David M Koelle, Anna Wald, David M Knipe, Lawrence Corey, Jia Zhu

Journal: Front Immunol

PubMed ID: 34552595

Doi: 10.3389/fimmu.2021.735643

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Lipopolysaccharide Is a 4-Aminoarabinose Donor to Exogenous Polyisoprenyl Phosphates through the Reverse Reaction of the Enzyme ArnT

Authors: Beth A Scarbrough, Colleen R Eade, Amanda J Reid, Tiffany C Williams, Jerry M Troutman

Journal: ACS Omega

PubMed ID: 34632229

Doi: 10.1021/acsomega.1c04036

Products & Services: Protein and Antibody Isolation

Resistance of SARS-CoV-2 Delta variant to neutralization by BNT162b2-elicited antibodies in Asians

Authors: Bei Wang, Yun Shan Goh, Siew-Wai Fong, Barnaby Edward Young, Eve Zi Xian Ngoh, Jean-Marc Chavatte, Siti Nazihah Mohd Salleh, Nicholas Kim-Wah Yeo, Siti Naqiah Amrun, Pei Xiang Hor, Chiew Yee Loh, Chia Yin Lee, Yi-Hao Chan, Zi Wei Chang, Matthew Zirui Tay, Angeline Rouers, Anthony Torres-Ruesta, Guillaume Carissimo, Mun Kuen Soh, Raphael Tze Chuen Lee, Yani Xu, Surinder Pada, Raymond Tzer Pin Lin, Yee-Sin Leo, David C Lye, Sebastian Maurer-Stroh, Lisa F P Ng, Laurent Renia, Cheng-I Wang

Journal: Lancet Reg Health West Pac

PubMed ID: 34568853

Doi: 10.1016/j.lanwpc.2021.100276

Products & Services: Recombinant Proteins

Expression of Biofilm-Degrading Enzymes in Plants and Automated High-Throughput Activity Screening Using Experimental Biofilms

Authors: P Opdensteinen, S J Dietz, B B Gengenbach, J F Buyel

Journal: Front Bioeng Biotechnol

PubMed ID: 34621728

Doi: 10.3389/fbioe.2021.708150

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Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin

Authors: Delia Susan-Resiga, Emmanuelle Girard, Rachid Essalmani, Anna Roubtsova, Jadwiga Marcinkiewicz, Rabeb M Derbali, Alexandra Evagelidis, Jae H Byun, Paul F Lebeau, Richard C Austin, Nabil G Seidah

Journal: J Biol Chem

PubMed ID: 34508778

Doi: 10.1016/j.jbc.2021.101177

Products & Services: Mammalian Expression

Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton

Authors: Katharina Vestre, Irene Persiconi, Marita Borg Distefano, Nadia Mensali, Noemi Antonella Guadagno, Marine Bretou, Sébastien Wälchli, Catharina Arnold-Schrauf, Oddmund Bakke, Marc Dalod, Ana-Maria Lennon-Dumenil, Cinzia Progida

Journal: J Cell Sci

PubMed ID: 34494097

Doi: 10.1242/jcs.259221

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Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions

Authors: Md Sifatul Islam, Md Soyib Hasan, Md Nazmul Hasan, Shamsul H Prodhan, Tahmina Islam, Ajit Ghosh

Journal: Sci Rep

PubMed ID: 34521910

Doi: 10.1038/s41598-021-97691-9

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Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted

Authors: Jeremy D Rubinstein, Xiang Zhu, Thomas Leemhuis, Giang Pham, Lorraine Ray, Sana Emberesh, Sonata Jodele, Shawn Thomas, Jose A Cancelas, Catherine M Bollard, Patrick J Hanley, Michael D Keller, Olivia Grimley, Diana Clark, Teri Clark, Cecilia S Lindestam Arlehamn, Alessandro Sette, Stella M Davies, Adam S Nelson, Michael S Grimley, Carolyn Lutzko

Journal: Blood Adv

PubMed ID: 34473237

Doi: 10.1182/bloodadvances.2021004456

Products & Services: Peptide Synthesis

Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys

Authors: Julien Baruteau, Sharon C Cunningham, Berna Seker Yilmaz, Dany P Perocheau, Simon Eaglestone, Derek Burke, Adrian J Thrasher, Simon N Waddington, Leszek Lisowski, Ian E Alexander, Paul Gissen

Journal: Mol Ther Methods Clin Dev

PubMed ID: 34703837

Doi: 10.1016/j.omtm.2021.09.005

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A Peptide-Based Assay Discriminates Individual Antibody Response to the COVID-19 Pfizer/BioNTech mRNA Vaccine

Authors: Immacolata Polvere, Serena Voccola, Alfredina Parrella, Gaetano Cardinale, Lucrezia Zerillo, Romualdo Varricchio, Jessica Raffaella Madera, Romania Stilo, Pasquale Vito, Tiziana Zotti

Journal: Vaccines (Basel)

PubMed ID: 34579224

Doi: 10.3390/vaccines9090987

Circular RNA hsa_circ_0001598 promotes programmed death-ligand-1-mediated immune escape and trastuzumab resistance via sponging miR-1184 in breast cancer cells

Authors: Li Huang, Jing Ma, Min Cui

Journal: Immunol Res

PubMed ID: 34559381

Doi: 10.1007/s12026-021-09237-w

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MicroRNA-140-5p represses chondrocyte pyroptosis and relieves cartilage injury in osteoarthritis by inhibiting cathepsin B/Nod-like receptor protein 3

Authors: Lei Zhang, Jianjun Qiu, Jixiang Shi, Shaoyang Liu, Hanlin Zou

Journal: Bioengineered

PubMed ID: 34565303

Doi: 10.1080/21655979.2021.1985342

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Ultrafast, sensitive, and portable detection of COVID-19 IgG using flexible organic electrochemical transistors

Authors: Hong Liu, Anneng Yang, Jiajun Song, Naixiang Wang, Puiyiu Lam, Yuenling Li, Helen Ka-Wai Law, Feng Yan

Journal: Sci Adv

PubMed ID: 34524851

Doi: 10.1126/sciadv.abg8387

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Loss of Function of and in Rice Promotes Early Maturing and Semi-Dwarfism in γ-Irradiated IWP and Genome-Edited Pusa Basmati-1

Authors: M T Andrew-Peter-Leon, Ramchander Selvaraj, K K Kumar, Mehanathan Muthamilarasan, Jeshima Khan Yasin, M Arumugam Pillai

Journal: Front Plant Sci

PubMed ID: 34630462

Doi: 10.3389/fpls.2021.714066

Products & Services: Molecular Biology Tools

An observational study of breakthrough SARS-CoV-2 Delta variant infections among vaccinated healthcare workers in Vietnam

Authors: Nguyen Van Vinh Chau, Nghiem My Ngoc, Lam Anh Nguyet, Vo Minh Quang, Nguyen Thi Han Ny, Dao Bach Khoa, Nguyen Thanh Phong, Le Mau Toan, Nguyen Thi Thu Hong, Nguyen Thi Kim Tuyen, Voong Vinh Phat, Le Nguyen Truc Nhu, Nguyen Huynh Thanh Truc, Bui Thi Ton That, Huynh Phuong Thao, Tran Nguyen Phuong Thao, Vo Trong Vuong, Tran Thi Thanh Tam, Ngo Tan Tai, Ho The Bao, Huynh Thi Kim Nhung, Nguyen Thi Ngoc Minh, Nguyen Thi My Tien, Nguy Cam Huy, Marc Choisy, Dinh Nguyen Huy Man, Dinh Thi Bich Ty, Nguyen To Anh, Le Thi Tam Uyen, Tran Nguyen Hoang Tu, Lam Minh Yen, Nguyen Thanh Dung, Le Manh Hung, Nguyen Thanh Truong, Tran Tan Thanh, Guy Thwaites, Le Van Tan

Journal: EClinicalMedicine

PubMed ID: 34608454

Doi: 10.1016/j.eclinm.2021.101143

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Glycosylation reduces the glycan-independent immunomodulatory effect of recombinant Orysata lectin in Drosophila S2 cells

Authors: Pengyu Chen, Kristof De Schutter, Sonia Serna, Simin Chen, Qun Yang, Niels-Christian Reichardt, Els J M Van Damme, Guy Smagghe

Journal: Sci Rep

PubMed ID: 34504130

Doi: 10.1038/s41598-021-97161-2

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Plant-Expressed Receptor Binding Domain of the SARS-CoV-2 Spike Protein Elicits Humoral Immunity in Mice

Authors: Puna Maya Maharjan, Jinyeong Cheon, Jiyun Jung, Haerim Kim, Jaewon Lee, Minjeong Song, Gi Uk Jeong, Youngchan Kwon, Byoungshik Shim, Sunghwa Choe

Journal: Vaccines (Basel)

PubMed ID: 34579215

Doi: 10.3390/vaccines9090978

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FGF21 ameliorates hepatic fibrosis by multiple mechanisms

Authors: Fanrui Meng, Mir Hassan Khoso, Kai Kang, Qi He, Yukai Cao, Xinghao Jiang, Wei Xiao, Deshan Li

Journal: Mol Biol Rep

PubMed ID: 34536190

Doi: 10.1007/s11033-021-06707-0

Products & Services: Protein and Antibody Isolation

Mitoxantrone dihydrochloride, an FDA approved drug, binds with SARS-CoV-2 NSP1 C-terminal

Authors: Prateek Kumar, ProfileTaniya Bhardwaj, ProfileRajanish Giri

Journal: biorxiv

Doi: doi.org/10.1101/2021.09.14.460211

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Orthogonal CRISPR-associated transposases for parallel and multiplexed chromosomal integration

Authors: Siqi Yang, Yiwen Zhang, Jiaqi Xu, Jiao Zhang, Jieze Zhang, Junjie Yang, Yu Jiang, Sheng Yang

Journal: Nucleic Acids Res

PubMed ID: 34478496

Doi: 10.1093/nar/gkab752

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Regulation of human mTOR complexes by DEPTOR

Authors: Matthias Wälchli, Karolin Berneiser, Francesca Mangia, Stefan Imseng, Louise-Marie Craigie, Edward Stuttfeld, Michael N Hall, Timm Maier

Journal: Elife

PubMed ID: 34519268

Doi: 10.7554/eLife.70871

Products & Services: Protein and Antibody Isolation

Pre-pandemic SARS-CoV-2 serological reactivity in rural malaria-experienced Cambodians

Authors: Jessica Manning, Irfan Zaidi, Chanthap Lon, Luz Angela Rosas, Jae-Keun Park, Aiyana Ponce, Jennifer Bohl, Sophana Chea, Maria Karkanitsa, Sokunthea Sreng, Huy Rekol, Char Meng Chour, Dominic Esposito, Jeffery K Taubenberger, Matthew J Memoli, Kaitlyn Sadtler, Patrick E Duffy, Fabiano Oliveira

Journal: medrxiv

PubMed ID: 34611671

Doi: 10.1101/2021.09.27.21264000

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Analytical and clinical performance of cPass neutralizing antibodies assay

Authors: Joanna Jung, Deepthi Rajapakshe, Christopher Julien, Sridevi Devaraj

Journal: Clin Biochem

PubMed ID: 34560062

Doi: 10.1016/j.clinbiochem.2021.09.008

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Kinase-Catalyzed Biotinylation to Map Cell Signaling Pathways: Application to Epidermal Growth Factor Signaling

Authors: Vindya Ramanayake-Mudiyanselage, D Maheeka Embogama, Mary Kay H Pflum

Journal: J Proteome Res

PubMed ID: 34491762

Doi: 10.1021/acs.jproteome.1c00562

Products & Services: Protein and Antibody Isolation

A Small Cysteine-Rich Phytotoxic Protein of Functions as Both Plant Defense Elicitor and Virulence Factor

Authors: Zi-Hui Zhang, Jing-Hao Jin, Gui-Lin Sheng, Yu-Ping Xing, Wang Liu, Xue Zhou, Yi-Qing Liu, Xiao-Ren Chen

Journal: Mol Plant Microbe Interact

PubMed ID: 33819070

Doi: 10.1094/MPMI-01-21-0025-R

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A Closer Look into FDA-EUA Approved Diagnostic Techniques of Covid-19

Authors: Hyunju Oh, Hyunjeong Ahn, Anubhav Tripathi

Journal: ACS Infect Dis

PubMed ID: 34569778

Doi: 10.1021/acsinfecdis.1c00268

Products & Services: Protein and Antibody Isolation

Consumption of gossypol increases fatty acid-amino acid conjugates in the cotton pests Helicoverpa armigera and Heliothis virescens

Authors: Corinna Krempl, Nicole Joußen, Michael Reichelt, Marco Kai, Heiko Vogel, David G Heckel

Journal: Arch Insect Biochem Physiol

PubMed ID: 34490676

Doi: 10.1002/arch.21843

Products & Services: Protein and Antibody Isolation

Post-transcriptional screen of cancer amplified genes identifies ERBB2/Her2 signaling as AU-rich mRNA stability-promoting pathway

Authors: Jenan Al-Matouq, Latifa Al-Haj, Maher Al-Saif, Khalid S A Khabar

Journal: Oncogenesis

PubMed ID: 34535639

Doi: 10.1038/s41389-021-00351-w

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Deletion of type VIII collagen reduces blood pressure, increases carotid artery functional distensibility and promotes elastin deposition

Authors: Amanda L Mohabeer, Jeffrey T Kroetsch, Meghan McFadden, Negin Khosraviani, Thomas J Broekelmann, Guangpei Hou, Hangjun Zhang, Yu-Qing Zhou, Minyao Wang, Anthony O Gramolini, Robert P Mecham, Scott P Heximer, Steffen-Sebastian Bolz, Michelle P Bendeck

Journal: Matrix Biol Plus

PubMed ID: 34693248

Doi: 10.1016/j.mbplus.2021.100085

Products & Services: Plasmid DNA Preparation

ReScribe: An Unrestrained Tool Combining Multiplex Recombineering and Minimal-PAM ScCas9 for Genome Recoding

Authors: Enrique Asin-Garcia, Maria Martin-Pascual, Luis Garcia-Morales, Richard van Kranenburg, Vitor A P Martins Dos Santos

Journal: ACS Synth Biol

PubMed ID: 34547891

Doi: 10.1021/acssynbio.1c00297

Products & Services: Plasmid DNA Preparation

MicroRNA-361 reduces the viability and migratory ability of pancreatic cancer cells via mediation of the MAPK/JNK pathway

Authors: Juan Wang, Zongjing Xie, Yan Liu, Weiguo Zhang, Tingting Ji

Journal: Exp Ther Med

PubMed ID: 34659511

Doi: 10.3892/etm.2021.10799

Products & Services: Plasmid DNA Preparation

Yeast Translational Activator Mss51p and Human ZMYND17 - Two Proteins with a Common Origin, but Different Functions

Authors: Maria V Baleva, Uliyana E Piunova, Ivan V Chicherin, Darya G Krasavina, Sergey A Levitskii, Piotr A Kamenski

Journal: Biochemistry (Mosc)

PubMed ID: 34565318

Doi: 10.1134/S0006297921090108

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Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase

Authors: Xida Zhao, Jingbo Liu, Chong Zhang, Ning Yu, Ze Lu, Shuwei Zhang, Yuchao Li, Qian Li, Junchao Liu, Dongjuan Liu, Yaping Pan

Journal: Int J Oral Sci

PubMed ID: 34593756

Doi: 10.1038/s41368-021-00136-2

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CLE14 functions as a "brake signal" to suppress age-dependent and stress-induced leaf senescence by promoting JUB1-mediated ROS scavenging in Arabidopsis

Authors: Zenglin Zhang, Cheng Liu, Kui Li, Xiaoxu Li, Mengmeng Xu, Yongfeng Guo

Journal: Mol Plant

PubMed ID: 34530165

Doi: 10.1016/j.molp.2021.09.006

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Enhancing Antigen Presentation and Inducing Antigen-Specific Immune Tolerance with Amphiphilic Peptides

Authors: Meng Li, Arata Itoh, Jingchao Xi, Chunsong Yu, Yuehong Wu, William M Ridgway, Haipeng Liu

Journal: J Immunol

PubMed ID: 34526376

Doi: 10.4049/jimmunol.1901301

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Characterization of HLA-A*02:01 MHC Immunopeptide Antigens Enhanced by Ultraviolet Photodissociation Mass Spectrometry

Authors: Eleanor Watts, Gregory K Potts, Damien B Ready, Alayna M George Thompson, Janice Lee, Edwin E Escobar, Melanie J Patterson, Jennifer S Brodbelt

Journal: Anal Chem

PubMed ID: 34553926

Doi: 10.1021/acs.analchem.1c01002

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Metformin inhibits hepatocellular carcinoma development by inducing apoptosis and pyroptosis through regulating FOXO3

Authors: Zetian Shen, Han Zhou, Aomei Li, Tiancong Wu, Xiaoqin Ji, Lei Guo, Xixu Zhu, Dagan Zhang, Xia He

Journal: Aging (Albany NY)

PubMed ID: 34546972

Doi: 10.18632/aging.203464

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Bioinformatics Analysis of a Functional ANGPT1 Variant That Interferes with miR-607 and Its Association with Susceptibility and Outcome of Ischemic Stroke in a Han Population

Authors: Ai-Nian Chen, Ling-Ling Zhong, Ke-Ju Ju, Hua Cao

Journal: Ther Clin Risk Manag

PubMed ID: 34611404

Doi: 10.2147/TCRM.S328964

Products & Services: PCR Cloning and Subcloning

A Single Dose of a Hybrid hAdV5-Based Anti-COVID-19 Vaccine Induces a Long-Lasting Immune Response and Broad Coverage against VOC

Authors: M Verónica López, Sabrina E Vinzón, Eduardo G A Cafferata, Felipe J Núñez, Ariadna Soto, Maximiliano Sanchez-Lamas, M Jimena Afonso, Diana Aguilar-Cortes, Gregorio D Ríos, Juliana T Maricato, Carla T Braconi, Vanessa B Silveira, Tatiane M Andrad, Tatiana C S Bonetti, Luiz M Ramos Janini, Manoel J B C Girão, Andrea S Llera, Karina A Gomez, Hugo H Ortega, Paula M Berguer, Osvaldo L Podhajcer

Journal: Vaccines (Basel)

PubMed ID: 34696219

Doi: 10.3390/vaccines9101106

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ORF3a Protein of Severe Acute Respiratory Syndrome Coronavirus 2 Inhibits Interferon-Activated Janus Kinase/Signal Transducer and Activator of Transcription Signaling Elevating Suppressor of Cytokine Signaling 1

Authors: Rong Wang, Xiaofeng Yang, Mingke Chang, Ziyang Xue, Weirong Wang, Liang Bai, Sihai Zhao, Enqi Liu

Journal: Front Microbiol

PubMed ID: 34650546

Doi: 10.3389/fmicb.2021.752597

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Plant Viral Nanoparticle Conjugated with Anti-PD-1 Peptide for Ovarian Cancer Immunotherapy

Authors: Aayushma Gautam, Veronique Beiss, Chao Wang, Lu Wang, Nicole F Steinmetz