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页码: 150/1026 每页显示数量

Efficient discovery of potential inhibitors for SARS-CoV-2 3C-like protease from herbal extracts using a native MS-based affinity-selection method

Authors: Dafu Zhu, Haixia Su, Changqiang Ke, Chunping Tang, Matthias Witt, Ronald J Quinn, Yechun Xu, Jia Liu, Yang Ye

Journal: J Pharm Biomed Anal

PubMed ID: 34929567

Doi: 10.1016/j.jpba.2021.114538

Products & Services: Protein Reagents and Products

Gene-specific quantification of nascent transcription following targeted degradation of endogenous proteins in cultured cells

Authors: Alissa D Guarnaccia, April M Weissmiller, William P Tansey

Journal: STAR Protoc

PubMed ID: 34917979

Doi: 10.1016/j.xpro.2021.101000

Products & Services: Codon Optimization

Identification and validation of potential mRNA- microRNA- long-noncoding RNA (mRNA-miRNA-lncRNA) prognostic signature for cervical cancer

Authors: Jie Wang, Chen Zhang

Journal: Bioengineered

PubMed ID: 33682613

Doi: 10.1080/21655979.2021.1890377

Products & Services: Polyclonal Antibody Services

Generation and utility of a single-chain fragment variable monoclonal antibody platform against a baculovirus expressed recombinant receptor binding domain of SARS-CoV-2 spike protein

Authors: Reda Salem, Alaa A El-Kholy, Fatma R Waly, Dalia Ayman, Aya Sakr, Mai Hussein

Journal: Mol Immunol

PubMed ID: 34915268

Doi: 10.1016/j.molimm.2021.12.006

Products & Services: Codon Optimization

Deep mutational scanning for therapeutic antibody engineering

Authors: Kyrin R Hanning, Mason Minot, Annmaree K Warrender, William Kelton, Sai T Reddy

Journal: Trends Pharmacol Sci

PubMed ID: 34895944

Doi: 10.1016/j.tips.2021.11.010

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Sequential dynamics of virological and serological changes in the serum of SARS-CoV-2 infected patients

Authors: Serge Ouoba, Mafumi Okimoto, Shintaro Nagashima, Yoshihiro Kitahara, Kei Miwata, Ko Ko, Bunthen E, Aya Sugiyama, Kazuaki Takahashi, Takemasa Sakaguchi, Toshiro Takafuta, Junko Tanaka

Journal: J Med Virol

PubMed ID: 34897741

Doi: 10.1002/jmv.27518

Products & Services: Protein Reagents and Products

A Pathogen-Inducible Rice NAC Transcription Factor ONAC096 Contributes to Immunity Against and pv by Direct Binding to the Promoters of , Magnaprothe oryzae, and Xanthomonas oryzaeoryzae OsRap26 OsWRKY62 OsPAL1

Authors: Hui Wang, Yan Bi, Yizhou Gao, Yuqing Yan, Xi Yuan, Xiaohui Xiong, Jiajing Wang, Jiayu Liang, Dayong Li, Fengming Song

Journal: Front Plant Sci

PubMed ID: 34956298

Doi: 10.3389/fpls.2021.802758

Products & Services: Catalog Peptides

Synergistic enzyme cocktail between levansucrase and inulosucrase for superb levan-type fructooligosaccharide synthesis

Authors: Karan Wangpaiboon, Methus Klaewkla, Thanapon Charoenwongpaiboon, Napas Vongkusolkit, Pawinee Panpetch, Kamontip Kuttiyawong, Wonnop Visessanguan, Rath Pichyangkura

Journal: Enzyme Microb Technol

PubMed ID: 34923315

Doi: 10.1016/j.enzmictec.2021.109960

Products & Services: Proteins, Expression, Isolation and Analysis

Gastrin producing syngeneic mesenchymal stem cells protect non-obese diabetic mice from type 1 diabetes

Authors: Marie-Claude Gaudreau, Radhika R Gudi, Gongbo Li, Benjamin M Johnson, Chenthamarakshan Vasu

Journal: Autoimmunity

PubMed ID: 34882054

Doi: 10.1080/08916934.2021.2012165

Products & Services: Gene Synthesis

Novel sequential immunocapture microflow LC/MS/MS approach to measuring PTH-Fc protein in human serum

Authors: Haixing Wang, Jiang Wu, Peng Pan, Thuy Nguyen, Michael Cwik, Ling Morgan

Journal: Bioanalysis

PubMed ID: 34894717

Doi: 10.4155/bio-2021-0233

Products & Services: Codon Optimization

Cryopreservation of network bioactivity and multi-lineage stromal cell differentiation potential within three-dimensional synthetic hydrogels

Authors:

Journal: Cryobiology

PubMed ID: 34922883

Doi: 10.1016/j.cryobiol.2021.12.003

Products & Services: Molecular Biology Reagents

Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells

Authors: Mark J Turner, Yukiko Sato, David Y Thomas, Kathy Abbott-Banner, John W Hanrahan

Journal: Cell Physiol Biochem

PubMed ID: 34936285

Doi: 10.33594/000000477

Products & Services: Proteins, Expression, Isolation and Analysis

Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells

Authors: Mark J Turner, Yukiko Sato, David Y Thomas, Kathy Abbott-Banner, John W Hanrahan

Journal: Cell Physiol Biochem

PubMed ID: 34936285

Doi: 10.33594/000000477

Products & Services: Proteins, Expression, Isolation and Analysis

Structural Insight into the Mechanism of PALB2 Interaction with MRG15

Authors: Jennifer Redington, Jaigeeth Deveryshetty, Lakshmi Kanikkannan, Ian Miller, Sergey Korolev

Journal: Genes (Basel)

PubMed ID: 34946951

Doi: 10.3390/genes12122002

Products & Services: Mutant Libraries

MiR-31 targets HSD17B14 and FSHR, and miR-20b targets HSD17B14 to affect apoptosis and steroid hormone metabolism of porcine ovarian granulosa cells

Authors: Siyuan Gao, Jing Zhao, Qinglei Xu, Yanli Guo, Mingzheng Liu, Chunlei Zhang, Allan P Schinckel, Bo Zhou

Journal: Theriogenology

PubMed ID: 34959084

Doi: 10.1016/j.theriogenology.2021.12.014

Products & Services: Proteins, Expression, Isolation and Analysis

COVID-19 mRNA booster vaccines elicit strong protection against SARS-CoV-2 Omicron variant in patients with cancer

Authors: Cong Zeng, John P Evans, Karthik Chakravarthy, Panke Qu, Sarah Reisinger, No-Joon Song, Mark P Rubinstein, Peter G Shields, Zihai Li, Shan-Lu Liu

Journal: Cancer Cell

PubMed ID: 34986328

Doi: 10.1016/j.ccell.2021.12.014

Products & Services: PCR Cloning and Subcloning

A metabolic labeling protocol to enrich myristoylated proteins from

Authors: Xin Gong, Yanwen Feng, Hongyun Tang

Journal: STAR Protoc

PubMed ID: 34917984

Doi: 10.1016/j.xpro.2021.101013

Products & Services: Proteins, Expression, Isolation and Analysis

BIX-01294 enhances the effect of chemotherapy on colorectal cancer by inhibiting the expression of stemness genes

Authors: Shikang Liu, Yihang Jiang, Hua Yang, Zhongke Hua, Yu Han, Cai Zhou, Shuling Xu, Shenglan Nie, Gaixia Xu, Xingsheng Shu, Xiaomei Wang

Journal: Biochem Biophys Res Commun

PubMed ID: 34979318

Doi: 10.1016/j.bbrc.2021.12.089

Products & Services: Recombinant Proteins

Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2

Authors: Lihong Liu, Sho Iketani, Yicheng Guo, Jasper F-W Chan, Maple Wang, Liyuan Liu, Yang Luo, Hin Chu, Yiming Huang, Manoj S Nair, Jian Yu, Kenn K-H Chik, Terrence T-T Yuen, Chaemin Yoon, Kelvin K-W To, Honglin Chen, Michael T Yin, Magdalena E Sobieszczyk, Yaoxing Huang, Harris H Wang, Zizhang Sheng, Kwok-Yung Yuen, David D Ho

Journal: Nature

PubMed ID: 35016198

Doi: 10.1038/s41586-021-04388-0

Products & Services: Catalog Antibody

Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men

Authors: Nina Le Bert, Wan Ni Chia, Wei Yee Wan, Alvin Kuo Jing Teo, Samuel Zeng-Rong Chong, Nicole Tan, Doreen Soek Chin Tan, Adeline Chia, Iain Beehuat Tan, Kamini Kunasegaran, Qin Xuan Chua, Mohammad Yazid Abdad, Aven Shan Hua Ng, Shawn Vasoo, Julian Xiao-Li Ang, Mao Sheng Lee, Louisa Sun, Jinyan Fang, Feng Zhu, Alex R Cook, Tar Choon Aw, Jingxiang Huang, Clarence Tam, Fong Sin Lee, Hannah Clapham, Enan Jun-Kang Goh, Monica Socheata Suor Peou, Shiow Pin Tan, Siew Kim Ong, Lin-Fa Wang, Antonio Bertoletti, Li Yang Hsu, Biauw Chi Ong

Journal: Emerg Microbes Infect

PubMed ID: 34709140

Doi: 10.1080/22221751.2021.1999777

Safety evaluation of the mouse TCRα - transduced T cell product in preclinical models in vivo and in vitro

Authors: Anastasiia Kalinina, Alexandra Bruter, Nadezhda Persiyantseva, Yulia Silaeva, Maria Zamkova, Ludmila Khromykh, Dmitry Kazansky

Journal: Biomed Pharmacother

PubMed ID: 34915667

Doi: 10.1016/j.biopha.2021.112480

Products & Services: Molecular Biology Reagents

Nanopore-based measurement of the interaction of P450cam monooxygenase and putidaredoxin at the single-molecule level

Authors: Hui Chen, Yao Lin, Yi-Tao Long, Shelley D Minteer, Yi-Lun Ying

Journal: Faraday Discuss

PubMed ID: 34889330

Doi: 10.1039/d1fd00042j

Products & Services: Plasmid DNA Preparation

Functional Characterization of Spinocerebellar Ataxia Associated Dynorphin A Mutant Peptides

Authors: Andreas Lieb, Germana Thaler, Barbara Fogli, Olga Trovato, Mitja Amon Posch, Teresa Kaserer, Luca Zangrandi

Journal: Biomedicines

PubMed ID: 34944698

Doi: 10.3390/biomedicines9121882

Products & Services: Catalog Peptides

Modifications of IL-6 by Hypochlorous Acids: Effects on Receptor Binding

Authors: Lori I Robins, Erika K Keim, Deborah B Robins, John S Edgar, John S Meschke, Philip R Gafken, Jeffrey F Williams

Journal: ACS Omega

PubMed ID: 34984290

Doi: 10.1021/acsomega.1c05297

Products & Services: Gene Synthesis

Rapid kinetics of calcium dissociation from plant calmodulin and calmodulin-like proteins and effect of target peptides

Authors: Francesca Troilo, Marco Pedretti, Carlo Travaglini-Allocatelli, Alessandra Astegno, Adele Di Matteo

Journal: Biochem Biophys Res Commun

PubMed ID: 34974297

Doi: 10.1016/j.bbrc.2021.12.077

Products & Services: Peptide Synthesis

An engineered oncolytic vaccinia virus encoding a single-chain variable fragment against TIGIT induces effective antitumor immunity and synergizes with PD-1 or LAG-3 blockade

Authors: Shuguang Zuo, Min Wei, Tiancheng Xu, Lingkai Kong, Bohao He, Shiqun Wang, Shibing Wang, Junhua Wu, Jie Dong, Jiwu Wei

Journal: J Immunother Cancer

PubMed ID: 34949694

Doi: 10.1136/jitc-2021-002843

Products & Services: GenParts™ DNA Fragments

The impact of benzo[a]pyrene on murine allergic airway inflammation via epigenetic remodeling

Authors: Xihua Wang, Shuyuan Guan, Lingbin Sun, Zhongliang Dai

Journal: Environ Toxicol Pharmacol

PubMed ID: 34883242

Doi: 10.1016/j.etap.2021.103782

Products & Services: Proteins, Expression, Isolation and Analysis

Adenovirus-mediated RNA interference against herpes simplex virus infection in vitro

Authors: Lin Chen, Zhi-Qiang Pan, Chang-Bin Zhai

Journal: Folia Histochem Cytobiol

PubMed ID: 34905214

Doi: 10.5603/FHC.a2021.0031

Products & Services: GenParts™ DNA Fragments

A unique NLRC4 receptor from echinoderms mediates Vibrio phagocytosis via rearrangement of the cytoskeleton and polymerization of F-actin

Authors: Kaiyu Chen, Siyuan Zhang, Yina Shao, Ming Guo, Weiwei Zhang, Chenghua Li

Journal: PLoS Pathog

PubMed ID: 34898657

Doi: 10.1371/journal.ppat.1010145

Products & Services: Recombinant Antibody Expression

A unique NLRC4 receptor from echinoderms mediates Vibrio phagocytosis via rearrangement of the cytoskeleton and polymerization of F-actin

Authors: Kaiyu Chen, Siyuan Zhang, Yina Shao, Ming Guo, Weiwei Zhang, Chenghua Li

Journal: PLoS Pathog

PubMed ID: 34898657

Doi: 10.1371/journal.ppat.1010145

Products & Services: Recombinant Antibody Expression

Convergent phenotypic evolution of rhodopsin for dim-light sensing across deep-diving vertebrates

Authors: Yu Xia , Yimeng Cui , Aishan Wang , Fangnan Liu , Hai Chi , Joshua H T Potter , Joseph Williamson , Xiaolan Chen , Stephen J Rossiter , Yang Liu

Journal: Mol Biol Evol

PubMed ID: 34463769

Doi: 10.1093/molbev/msab262

Products & Services: Catalog Peptides

Comparison of SARS-CoV-2 Antibody Response 4 Weeks After Homologous vs Heterologous Third Vaccine Dose in Kidney Transplant Recipients: A Randomized Clinical Trial

Authors: Roman Reindl-Schwaighofer, Andreas Heinzel, Manuel Mayrdorfer, Rhea Jabbour, Thomas M Hofbauer, Anne Merrelaar, Michael Eder, Florina Regele, Konstantin Doberer, Paul Spechtl, Constantin Aschauer, Maximilian Koblischke, Christopher Paschen, Farsad Eskandary, Karin Hu, Barbara Öhler, Arshdeep Bhandal, Sabine Kleibenböck, Rahel I Jagoditsch, Bianca Reiskopf, Florian Heger, Gregor Bond, Georg A Böhmig, Robert Strassl, Lukas Weseslindtner, Alexander Indra, Judith H Aberle, Michael Binder, Rainer Oberbauer

Journal: JAMA Intern Med

PubMed ID: 34928302

Doi: 10.1001/jamainternmed.2021.7372

Products & Services: Protein Reagents and Products

Bio inspired growth factor loaded self assembling peptide nano hydrogel for chronic wound healing

Authors: E Santhini, R Parthasarathy, M Shalini, S Dhivya, L Amalorpava Mary, V Vijaya Padma

Journal: Int J Biol Macromol

PubMed ID: 34920072

Doi: 10.1016/j.ijbiomac.2021.12.026

Products & Services: Catalog Antibody

Induction of Th1 and Th2 in the protection against SARS-CoV-2 through mucosal delivery of an adenovirus vaccine expressing an engineered spike protein

Authors: Nai-Hsiang Chung, Ying-Chin Chen, Shiu-Ju Yang, Yu-Ching Lin, Horng-Yunn Dou, Lily Hui-Ching Wang, Ching-Len Liao, Yen-Hung Chow

Journal: Vaccine

PubMed ID: 34952759

Doi: 10.1016/j.vaccine.2021.12.024

Products & Services: Insect Expression

SARS-CoV-2 recombinant proteins stimulate distinct cellular and humoral immune response profiles in samples from COVID-19 convalescent patients

Authors: Laís Teodoro da Silva, Marina Mazzilli Ortega, Bruna Tiaki Tiyo, Isabelle Freire Tabosa Viana, Tayná Evily de Lima, Tania Regina Tozetto-Mendoza, Luanda Mara da Silva Oliveira, Franciane Mouradian Emidio Teixeira, Roberto Dias Lins, Alexandre de Almeida, Maria Cassia Mendes-Correa, Alberto Jose da Silva Duarte, Telma Miyuki Oshiro

Journal: Clinics (Sao Paulo)

PubMed ID: 34878034

Doi: 10.6061/clinics/2021/e3548

Products & Services: Protein Reagents and Products

Porcine Genome-Wide CRISPR Screen Identifies the Golgi Apparatus Complex Protein COG8 as a Pivotal Regulator of Influenza Virus Infection

Authors: Ao Zhou, Wenhua Zhang, Xia Dong, Bin Tang

Journal: CRISPR J

PubMed ID: 34935491

Doi: 10.1089/crispr.2021.0054

Products & Services: Oligo pool

Anisotropic Rod-Shaped Particles Influence Injectable Granular Hydrogel Properties and Cell Invasion

Authors: Taimoor H Qazi, Jingyu Wu, Victoria G Muir, Shoshana Weintraub, Sarah E Gullbrand, Daeyeon Lee, David Issadore, Jason A Burdick

Journal: Adv Mater

PubMed ID: 34932833

Doi: 10.1002/adma.202109194

Products & Services: Peptide Synthesis

Development of competitive and noncompetitive immunoassays for clothianidin with high sensitivity and specificity using phage-displayed peptides

Authors: Tianyang You, Yuan Ding, He Chen, Guangyue Song, Lianrun Huang, Minghua Wang, Xiude Hua

Journal: J Hazard Mater

PubMed ID: 34896720

Doi: 10.1016/j.jhazmat.2021.128011

Products & Services: Mutant Libraries

A New Testing Platform Using Fingerstick Blood for Quantitative Antibody Response Evaluation after SARS-CoV-2 Vaccination

Authors: Jinwei Du, Dayu Zhang, Joseph A Pathakamuri, Daniel Kuebler, Ying Yang, Yulia Loginova, Eric Chu, Roberta Madej, Jocelyn V Neves, Brianna Singer, Holly Radke, Naomi Spencer, Elizabeth Rizk, Aiguo Zhang, Chuanyi M Lu, Michael Y Sha

Journal: Emerg Microbes Infect

PubMed ID: 34951566

Doi: 10.1080/22221751.2021.2023328

Products & Services: Protein Reagents and Products

Rapid directed molecular evolution of fluorescent proteins in mammalian cells

Authors: Siranush Babakhanova, Erica E Jung, Kazuhiko Namikawa, Hanbin Zhang, Yangdong Wang, Oksana M Subach, Dmitry A Korzhenevskiy, Tatiana V Rakitina, Xian Xiao, Wenjing Wang, Jing Shi, Mikhail Drobizhev, Demian Park, Lea Eisenhard, Hongyun Tang, Reinhard W Köster, Fedor V Subach, Edward S Boyden, Kiryl D Piatkevich

Journal: Protein Sci

PubMed ID: 34913537

Doi: 10.1002/pro.4261

Products & Services: Gene Synthesis

pH Low Insertion Peptide-Modified Programmed Cell Death-Ligand 1 Potently Suppresses T-Cell Activation Under Acidic Condition

Authors: Ying Sun, Linhan Hu, Peng Yang, Min Zhang, Xinwei Wang, He Xiao, Chunxia Qiao, Jing Wang, Longlong Luo, Jiannan Feng, Yuanqiang Zheng, Yi Wang, Yanchun Shi, Guojiang Chen

Journal: Front Immunol

PubMed ID: 35003115

Doi: 10.3389/fimmu.2021.794226

Products & Services: Recombinant Antibody Expression

Construction, Investigation and Application of TEV Protease Variants with Improved Oxidative Stability

Authors: Enkhtuya Bayar, Yuanyuan Ren, Yinghua Chen, Yafang Hu, Shuncheng Zhang, Xuelian Yu, Jun Fan

Journal: J Microbiol Biotechnol

PubMed ID: 34528919

Doi: 10.4014/jmb.2106.06075

Products & Services: Plasmid DNA Preparation

Rhomboid-like Protein 5 Provided Partial Protection against Homologous Challenge in Forms of Recombinant Protein and DNA Plasmid in Chickens

Authors: Di Tian, Xiaoqian Liu, Xiangrui Li, Lixin Xu, Ruofeng Yan, Xiaokai Song

Journal: Vaccines (Basel)

PubMed ID: 35062693

Doi: 10.3390/vaccines10010032

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Selective suppression of IL-10 transcription by calcineurin in dendritic cells through inactivation of CREB

Authors: Xiuyuan Lu, Masatsugu Oh-Hora, Kiyoshi Takeda, Sho Yamasaki

Journal: Int Immunol

PubMed ID: 34953165

Doi: 10.1093/intimm/dxab112

Products & Services: Gene Synthesis

Simplified Point-of-Care Full SARS-CoV-2 Genome Sequencing Using Nanopore Technology

Authors: Anton Pembaur, Erwan Sallard, Patrick Philipp Weil, Jennifer Ortelt, Parviz Ahmad-Nejad, Jan Postberg

Journal: Microorganisms

PubMed ID: 34946199

Doi: 10.3390/microorganisms9122598

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Bak and Bcl-xL Participate in Regulating Sensitivity of Solid Tumor Derived Cell Lines to Mcl-1 Inhibitors

Authors: Viacheslav V Senichkin, Nikolay V Pervushin, Alexey V Zamaraev, Elena V Sazonova, Anton P Zuev, Alena Y Streletskaia, Tatiana A Prikazchikova, Timofei S Zatsepin, Olga V Kovaleva, Elena M Tchevkina, Boris Zhivotovsky, Gelina S Kopeina

Journal: Cancers (Basel)

PubMed ID: 35008345

Doi: 10.3390/cancers14010181

Products & Services: Plasmid DNA Preparation

Cloning and functional identification of setaria italica somatic embryogenesis receptor-like kinase1 gene (SiSERK1)

Authors: Guofan Wu, Wenbo Li, Nongfu Tian, Xin Wang, Wangze Wu, Sheng Zheng

Journal: Gene

PubMed ID: 34902513

Doi: 10.1016/j.gene.2021.146119

Products & Services: Proteins, Expression, Isolation and Analysis

Motif-driven protein binder design towards transferrin receptor helical domain

Authors: Dick J Sjöström, Camilla Mohlin, Elena Ambrosetti, Scott J Garforth, Ana I Teixeira, Sinisa Bjelic

Journal: FEBS J

PubMed ID: 34862739

Doi: 10.1111/febs.16311

Products & Services: Proteins, Expression, Isolation and Analysis

Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice

Authors: Moustafa T Mabrouk, Kevin Chiem, Edurne Rujas, Wei-Chiao Huang, Dushyant Jahagirdar, Breandan Quinn, Meera Surendran Nair, Ruth H Nissly, Victoria S Cavener, Nina R Boyle, Ty A Sornberger, Suresh V Kuchipudi, Joaquin Ortega, Jean-Philippe Julien, Luis Martinez-Sobrido, Jonathan Lovell

Journal: Sci Adv

PubMed ID: 34851667

Doi: 10.1126/sciadv.abj1476

Products & Services: Proteins, Expression, Isolation and Analysis

Antifungal activity and mode of action of synthetic peptides derived from the tick OsDef2 defensin

Authors: Kabuzi R Mbuayama, Helena Taute, Adam A Strӧmstedt, Megan J Bester, Anabella R M Gaspar

Journal: J Pept Sci

PubMed ID: 34866278

Doi: 10.1002/psc.3383

Products & Services: Peptide Synthesis

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