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页码: 82/5234 每页显示数量

Discovery, Herbicidal Activity and Biosynthesis of a Novel Natural Tetramic Acid from Alternaria Species

Authors: He Wang, Yanjing Guo, Qing Liu, Jing Zhang, Qianlong Zhang, Mingying Yang, Qizhen Chen, Sheng Qiang, Bernal E Valverde, Shiguo Chen

Journal: Advanced Science

PubMed ID: 40278415

Doi: 10.1002/advs.202416188

Products & Services: Gene Synthesis

Novel Bivalent mRNA-LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Authors: Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan-Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar-Haim, Orit Redy-Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud

Journal: Advanced Science

PubMed ID: 40279638

Doi: 10.1002/advs.202501286

Products & Services: Peptide Synthesis

Macrophages direct location-dependent recall of B cell memory to vaccination

Authors: Rama Dhenni, Alexandra Carey Hoppé, Arnold Reynaldi, Wunna Kyaw, Nathalie Tricia Handoko, Abigail K. Grootveld, Yuki Honda Keith, Nayan Deger Bhattacharyya, Holly I. Ahel, Aiden Josiah Telfser, Andrew N. McCorkindale, Seyhan Yazar, Christina H.T. Bui, James T. Smith, Weng Hua Khoo, Mollie Boyd, Solange Obeid, Brad Milner, Mitchell Starr, Fabienne Brilot, Tri Giang Phan

Journal: Molecular Therapy

Doi: 10.1016/j.cell.2025.04.005

Products & Services: Peptide Synthesis

Structure and inhibition mechanisms of Mycobacterium tuberculosis essential transporter efflux protein A

Authors: Nitesh Kumar Khandelwal, Meghna Gupta, James E Gomez, Sulyman Barkho, Ziqiang Guan, Ashley Y Eng, Tomohiko Kawate, Sree Ganesh Balasubramani, Andrej Sali, Deborah T Hung, Robert M Stroud

Journal: Nature Communications

PubMed ID: 40169593

Doi: 10.1038/s41467-025-58133-6

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Structural basis for allosteric modulation of M. tuberculosis proteasome core particle

Authors: Madison Turner, Adwaith B. Uday, Algirdas Velyvis, Enrico Rennella, Natalie Zeytuni & Siavash Vahidi

Journal: Nature Communications

PubMed ID: 40169579

Doi: 10.1038/s41467-025-58430-0

Products & Services: Peptide Synthesis

Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance

Authors: Amanda L. Waterbury, Jonatan Caroli, Olivia Zhang, Paloma R. Tuttle, Chao Liu, Jiaming Li, Ji Sung Park, Samuel M. Hoenig, Marco Barone, Airi Furui, Andrea Mattevi & Brian B. Liau

Journal: Nature Communications

PubMed ID: 40175327

Doi: 10.1038/s41467-025-57477-3

Products & Services: Peptide Synthesis

CodonTransformer: a multispecies codon optimizer using context-aware neural networks

Authors: Adibvafa Fallahpour, Vincent Gureghian, Guillaume J. Filion, Ariel B. Lindner & Amir Pandi

Journal: Nature Communications

PubMed ID: 40180930

Doi: 10.1038/s41467-025-58588-7

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Mechanistic insights into the structure-based design of a CspZ-targeting Lyme disease vaccine

Authors: Kalvis Brangulis, Jill Malfetano, Ashley L. Marcinkiewicz, Alan Wang, Yi-Lin Chen, Jungsoon Lee, Zhuyun Liu, Xiuli Yang, Ulrich Strych, Dagnija Tupina, Inara Akopjana, Maria-Elena Bottazzi, Utpal Pal, Ching-Lin Hsieh, Wen-Hsiang Chen & Yi-Pin Lin

Journal: Nature Communications

PubMed ID: 40189575

Doi: 10.1038/s41467-025-58182-x

Products & Services: Gene Synthesis

Modified pegRNAs mitigate scaffold-derived prime editing by-products

Authors: Panagiotis Antoniou, Louis Dacquay, Hanna Mårtensson, Katja Madeyski-Bengtson, Anna-Lena Loyd, Anna Shiriaeva, Euan Gordon, Salman Mustfa, George Thom, Pei-Pei Hsieh, Saša Šviković, Mike Firth, Nina Akrap, Marcello Maresca & Martin Peterka

Journal: Nature Communications

PubMed ID: 40204736

Doi: 10.1038/s41467-025-58653-1

Products & Services: Gene Synthesis

Mutant huntingtin induces neuronal apoptosis via derepressing the non-canonical poly(A) polymerase PAPD5

Authors: Zhefan Stephen Chen, Shaohong Isaac Peng, Lok I Leong, Terence Gall-Duncan, Nathan Siu Jun Wong, Tsz Ho Li, Xiao Lin, Yuming Wei, Alex Chun Koon, Junzhe Huang, Jacquelyne Ka-Li Sun, Clinton Turner, Lynette Tippett, Maurice A. Curtis, Richard L. M. Faull, Kin Ming Kwan, Hei-Man Chow, Ho Ko, Ting-Fung Chan, Kevin Talbot, Christopher E. Pearson & Ho Yin Edwin Chan

Journal: Nature Communications

PubMed ID: 40204699

Doi: 10.1038/s41467-025-58618-4

Products & Services: Gene Synthesis