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A ternary switch model governing ERα ligand binding domain conformation
Authors: Daniel P McDougal, Jordan L Pederick, Scott J Novick, Blagojce Jovcevski, Annmaree K Warrender, Bruce D Pascal, Patrick R Griffin, John B Bruning
Journal: Nature Communications
PubMed ID: 41285747
Doi: 10.1038/s41467-025-65323-9.
Products & Services: Catalog Peptides   
A de novo missense variant in MIDEAS results in increased deacetylase activity of the MiDAC HDAC complex causing a neurodevelopmental syndrome
Authors: Louise Fairall, Kristupas Sirvydis, Robert E Turnbull, Suzan Jg Knottnerus, Oksana Gonchar, Frederick W Muskett, Rebekah Jukes-Jones, Lonneke van Brussel, Ellen van de Geer, Koen van Gassen, Paul Badenhorst, Diana Johnson, Paulien A Terhal, Peter M van Hasselt, Richard H van Jaarsveld, John Wr Schwabe
Journal: Nature Communications
PubMed ID: 41290615
Doi: 10.1038/s41467-025-65472-x.
Products & Services: Catalog Peptides   
Nivolumab plus ipilimumab induce hyper-progression in renal medullary carcinoma: results of a phase II trial and preclinical evidence
Authors: Melinda Soeung, Xinmiao Yan, Ciro Zanca, Jing Qian, Menuka Karki, Fei Duan, Hania Khan, Li Zhang, David H Peng, Mariah Williams, Rong He, Ziheng Chen, Luigi Perelli, Jianfeng Chen, Rebecca S Tidwell, Pankaj K Chauhan, Courtney N Le, Truong N A Lam, Nirjar Bhattacharya, Rutvi Shah, I-Lin Ho, Jason P Gay, Caroline C Carrillo, Ningping Feng, Kang Le, Guang Gao, Teresa L Perry, Faika Mseeh, Yongying Jiang, Quanyun A Xu, Niki Marie Zacharias, Rahul A Sheth, Tharakeswara K Bathala, Priya Rao, Najat C Daw, Durga N Tripathi, Cheryl L Walker, Mohammad M Mohammad, Jianhua Zhang, Guangchun Han, Yanshuo Chu, Ruiping Wang, Minghao Dang, Enyu Dai, Fuduan Peng, Yunhe Liu, Akshaya Jadhav, Wenhua Lang, Claudio A Arrechedera, Leticia Campos Clemente, Edwin R Parra, Hsinyi Lu, Cara L Haymaker, Ignacio I Wistuba, Andrew Futreal, Andrea Viale, Michael J Soth, Philip Jones, Joseph R Marszalek, Timothy Heffernan, Giulio F Draetta, Nizar M Tannir, Jianjun Gao, Linghua Wang, Giannicola Genovese, Pavlos Msaouel
Journal: Nature Communications
PubMed ID: 41290625
Doi: 10.1038/s41467-025-65462-z.
Products & Services: Molecular Biology Tools   
Cancer-associated snaR-A noncoding RNA interacts with core splicing machinery and disrupts processing of mRNA subpopulations
Authors: Sihang Zhou, Simon Lizarazo, Sandip Chorghade, Leela Mouli, Ruiying Cheng, Rajendra K C, Auinash Kalsotra, Kevin Van Bortle
Journal: Nature Communications
PubMed ID: 41290606
Doi: 10.1038/s41467-025-65448-x.
Products & Services: Molecular Biology Reagents   
Potential of ferulic acid as a food-derived cardioprotective agent targeting mitochondrial dysfunction
Authors: Duanrui Cao, Lina Huang, Xiaowei Lu, Junhua Meng, Wenhong Li, Delin Duan, Qianqian Wang, Cuiping Liu, Zidong Qiu, Ni Zhang
Journal: Food Bioscience
Doi: //doi.org/10.1016/j.fbio.2025.107704
Products & Services: Custom DNA/RNA Oligos   
Enhanced antigen presentation by macrophages promotes human atherosclerosis progression: therapeutic implications
Authors: Yuhuai Xie, Que Wu, Yunhui Jia, Lianping Cheng, Yaru Tian, Xian Yang, Wei Wang, Wei Xu, Zhen Zhao, Yuanyuan Wei
Journal: European heart journal
PubMed ID: 41217874
Doi: 10.1093/eurheartj/ehaf878
Products & Services: Synthetic Guide RNA   
De N ovo -Designed Miniprotein Inhibits the Enzymatic Activity of the SARS-CoV 2 Main Protease
Authors: Tayn E. Lima; Emerson G. Moreira; Danilo F. Co lho; Carlos H. B. Cruz; Rafael Dhalia; Bruno H. S. Leite; L cya S. Xavier; Marta Perez Illana; Gabriel L. Wallau; Isabelle F. T. Viana; Roberto D. Lins
Journal: Journal of chemical information and modeling
PubMed ID: 41060276
Doi: 10.1021/acs.jcim.5c01708
Genetics of cystogenesis in base edited human organoids reveal therapeutic strategies for polycystic kidney disease
Authors: Courtney E. Vishy; Chardai Thomas; Thomas Vincent; Daniel K. Crawford; Matthew M. Goddeeris; Benjamin S. Freedman
Journal: Cell Stem Cell
PubMed ID: 38579684
Doi: 10.1016/j.stem.2024.03.005
Products & Services: Plasmid DNA Preparation   
Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains
Authors: Monica Rosas-Lemus; George Minasov; Joseph S. Brunzelle; Taha Y. Taha; Sofia Lemak; Shaohui Yin; Ludmilla Shuvalova; Julia Rosecrans; Kanika Khanna; H Steven Seifert; Alexei Savchenko; Peter J. Stogios; Melanie Ott; Karla J. F. Satchell
Journal: biorxiv
PubMed ID: 39185168
Doi: 10.1101/2024.08.13.607777
Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains
Authors: Monica Rosas-Lemus; George Minasov; Joseph S. Brunzelle; Taha Y. Taha; Sofia Lemak; Shaohui Yin; Ludmilla Shuvalova; Julia Rosecrans; Kanika Khanna; H Steven Seifert; Alexei Savchenko; Peter J. Stogios; Melanie Ott; Karla J. F. Satchell
Journal: biorxiv
PubMed ID: 39185168
Doi: 10.1101/2024.08.13.607777
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