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A chemically controlled Cas9 switch enables temporal modulation of diverse effectors
Authors: Cindy T Wei, Nicholas A Popp, Omri Peleg, Rachel L Powell, Elhanan Borenstein, Dustin J Maly, Douglas M Fowler
Journal: Nat Chem Biol
PubMed ID: 36879061
Doi: 10.1038/s41589-023-01278-6
Products & Services: Codon Optimization   
Antitumor effect of neoantigen-reactive T cells combined with PD1 inhibitor therapy in mouse lung cancer
Authors: Huan Qin, Haiyan Hu, Ximing Liao, Pei Zhao, Wenjuan He, Xiaoping Su, Jiaxing Sun, Qiang Li
Journal: J Cancer Res Clin Oncol
PubMed ID: 36933035
Doi: 10.1007/s00432-023-04683-5
Products & Services: Peptide Synthesis   
SARS-CoV-2-related bat virus behavior in human-relevant models sheds light on the origin of COVID-19
Authors: Sarah Temmam, Xavier Montagutelli, Cécile Herate, Flora Donati, Béatrice Regnault, Mikael Attia, Eduard Baquero Salazar, Delphine Chretien, Laurine Conquet, Grégory Jouvion, Juliana Pipoli Da Fonseca, Thomas Cokelaer, Faustine Amara, Francis Relouzat, Thibaut Naninck, Julien Lemaitre, Nathalie Derreudre-Bosquet, Quentin Pascal, Massimiliano Bonomi, Thomas Bigot, Sandie Munier, Felix A Rey, Roger Le Grand, Sylvie van der Werf, Marc Eloit
Journal: EMBO Rep
PubMed ID: 36876574
Doi: 10.15252/embr.202256055
Products & Services: Recombinant Proteins   
Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines
Authors: Thayne H Dickey, Rui Ma, Sachy Orr-Gonzalez, Tarik Ouahes, Palak Patel, Holly McAleese, Brandi Butler, Elizabeth Eudy, Brett Eaton, Michael Murphy, Jennifer L Kwan, Nichole D Salinas, Michael R Holbrook, Lynn E Lambert, Niraj H Tolia
Journal: Cell Rep
PubMed ID: 36943870
Doi: 10.1016/j.celrep.2023.112266
Products & Services: Recombinant Proteins   
On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation
Authors: Niying Chua, Yee Hwa Wong, Abbas El Sahili, Chuan Fa Liu, Julien Lescar
Journal: FEBS Open Bio
PubMed ID: 36788723
Doi: 10.1002/2211-5463.13575
Products & Services: Peptide Synthesis   
RHINO restricts MMEJ activity to mitosis
Authors: Alessandra Brambati, Olivia Sacco, Sarina Porcella, Joshua Heyza, Mike Kareh, Jens C Schmidt, Agnel Sfeir
Journal: biorxiv
PubMed ID: 36993461
Doi: 10.1101/2023.03.16.532763
Products & Services: Recombinant Proteins   
Myosin-X recruits lamellipodin to filopodia tips
Authors: Ana Popović, Mitro Miihkinen, Sujan Ghimire, Rafael Saup, Max L B Grönloh, Neil J Ball, Benjamin T Goult, Johanna Ivaska, Guillaume Jacquemet
Journal: J Cell Sci
PubMed ID: 36861887
Doi: 10.1242/jcs.260574
Products & Services: Gene Synthesis   
Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders
Authors: Elżbieta Wątor , Piotr Wilk , Artur Biela, Michał Rawski , Krzysztof M Zak, Wieland Steinchen , Gert Bange, Sebastian Glatt , Przemysław Grudnik
Journal: Nature Communications
PubMed ID: 36973244
Doi: 10.1038/s41467-023-37305-2
Products & Services: Gene Synthesis   Gene Synthesis   
Mucus-penetrating nonviral gene vaccine processed in the epithelium for inducing advanced vaginal mucosal immune responses
Authors: Qunjie Bi, Xu Song, Yangyang Zhao, Xueyi Hu, Huan Yang, Rongrong Jin, Yu Nie
Journal: Acta Pharmacuetica Sinica.B
PubMed ID: 36970203
Doi: 10.1016/j.apsb.2022.11.004
Products & Services: Peptide Synthesis   
A riboswitch separated from its ribosome-binding site still regulates translation
Authors: Griffin M Schroeder, Olayinka Akinyemi, Jeffrey Malik, Caroline M Focht, Elizabeth M Pritchett, Cameron D Baker, James P McSally, Jermaine L Jenkins, David H Mathews, Joseph E Wedekind
Journal: Nucleic Acids Research
PubMed ID: 36762498
Doi: 10.1093/nar/gkad056.
Products & Services: Gene Synthesis   

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