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Comparison of mouse models of microbial experience reveals differences in microbial diversity and response to vaccination

Authors: Autumn E Sanders, Henriette Arnesen, Frances K Shepherd, Dira S Putri, Jessica K Fiege, Mark J Pierson, Shanley N Roach, Harald Carlsen, David Masopust, Preben Boysen, Ryan A Langlois

Journal: mSphere

PubMed ID: 38286428

Doi: 10.1128/msphere.00654-23

Products & Services: Recombinant Proteins

A small-molecule activation mechanism that directly opens the KCNQ2 channel

Authors: Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiangtao Guo, Qiansen Zhang, Huaiyu Yang

Journal: Nat Chem Biol

PubMed ID: 38167918

Doi: 10.1038/s41589-023-01515-y

Products & Services: Gene Synthesis

Functional characterization of the dimeric form of PDGF-derived fusion peptide fabricated based on theoretical arguments

Authors: Maryam Sadeghi-Ardebili, Sadegh Hasannia, Bahareh Dabirmanesh, Ramazan Ali Khavari-Nejad

Journal: Sci Rep

PubMed ID: 38200288

Doi: 10.1038/s41598-024-51707-2

Products & Services: Peptide Synthesis

Extracellular vesicle-mediated gene editing for the treatment of non-syndromic progressive hearing loss in adult mice

Authors: Xiaoshu Pan; Peixin Huang; Samantha S. Ali; Bryan Renslo; Zachary Greenberg; Nina Erwin; Yanjun Li; Zuo Ding; Tarun E Hutchinson; Athanasia Warnecke; Natalia E. Fernandez; Hinrich Staecker; Mei He

Journal: Science Translational Medicine

PubMed ID: 41223249

Doi: 10.1126/scitranslmed.adn3993

Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors

Authors: Nishma Gupta; Nicole Trainor; Mona Radwan; Stephanie Nguyen; Luke Duncan; Andrew X. Tang; Julia Beveridge; Natasha Silke; Jumana Yousef; Ceren Bilgilier; Johannes Wachter; Peter Greb; Zuzana Jandova; J n Elia ; Sara Kopf; Thomas Gerstberger; Peggy Stolt-Bergner; Nina Braun; Harald Weinstabl; Darryl B. McConnell; Federico Mauri; Isabelle S. Lucet; John Silke; Nicola E. A. Chessum; Michael J. Roy

Journal: Communications Chemistry

PubMed ID: 41554911

Doi: 10.1038/s42004-025-01871-x

Recombinant protein expression in proteome-reduced cells under aerobic and oxygen-limited regimes

Authors: Alvaro R Lara, Jose Utrilla, Luz María Martínez, Niels Krausch, Lucas Kaspersetz, David Hidalgo, Nicolas Cruz-Bournazou, Peter Neubauer, Juan-Carlos Sigala, Guillermo Gosset, Jochen Büchs

Journal: Biotechnol Bioeng

PubMed ID: 38178599

Doi: 10.1002/bit.28645

Products & Services: Molecular Biology Reagents

Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

Authors: Ayijiang Yisimayi, Weiliang Song, Jing Wang, Fanchong Jian, Yuanling Yu, Xiaosu Chen, Yanli Xu, Sijie Yang, Xiao Niu, Tianhe Xiao, Jing Wang , Lijuan Zhao, Haiyan Sun, Ran An, Na Zhang, Yao Wang, Peng Wang, Lingling Yu, Zhe Lv, Qingqing Gu, Fei Shao, Ronghua Jin, Zhongyang Shen, Xiaoliang Sunney Xie, Youchun Wang, Yunlong Cao

Journal: Nature

PubMed ID: 37993710

Doi: 10.1038/s41586-023-06753-7

Products & Services: Gene Synthesis

Structural basis of Gabija anti-phage defence and viral immune evasion

Authors: Sadie P Antine, Alex G Johnson, Sarah E Mooney, Azita Leavitt, Megan L Mayer, Erez Yirmiya, Gil Amitai, Rotem Sorek, Philip J Kranzusch

Journal: Nature

PubMed ID: 37992757

Doi: 10.1038/s41586-023-06855-2

Products & Services: Gene Synthesis

A synthetic differentiation circuit in Escherichia coli for suppressing mutant takeover

Authors: David S Glass 1, Anat Bren 2, Elizabeth Vaisbourd 2, Avi Mayo 2, Uri Alon

Journal: Cell

PubMed ID: 38320549

Doi: 10.1016/j.cell.2024.01.024

Products & Services: Plasmid DNA Preparation

Sirtuin 3 is required for the dexmedetomidine-mediated alleviation of inflammation and oxidative stress in nephritis

Authors: Kai Lu , Xinlong Li , Jie Wu

Journal: Immunity

PubMed ID: 38270316

Doi: 10.1002/iid3.1135

Products & Services: Custom DNA/RNA Oligos